Regulation of vascular endothelial junction stability and remodeling through Rap1-Rasip1 signaling

Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling

(2013) C. W. Wilson et al.   BLOOD

Distinct functions for Rap1 signaling in vascular morphogenesis and dysfunction

(2013) Magdalena Chrzanowska-Wodnicka   EXPERIMENTAL CELL RESEARCH

Exchange protein activated by cAMP 1 (Epac1)-deficient mice develop β-cell dysfunction and metabolic syndrome

(2013) Alan K. L. Kai et al.   FASEB JOURNAL

Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization

(2013) Koji Ando et al.   JOURNAL OF CELL BIOLOGY

Mechanosensitive systems at the cadherin-F-actin interface

(2013) S. Huveneers et al.   JOURNAL OF CELL SCIENCE

Endothelial adherens junctions at a glance

(2013) E. Dejana et al.   JOURNAL OF CELL SCIENCE

p120-catenin and β-catenin differentially regulate cadherin adhesive function

(2013) Rebecca G. Oas et al.   MOLECULAR BIOLOGY OF THE CELL

EndMT contributes to the onset and progression of cerebral cavernous malformations

(2013) Luigi Maddaluno et al.   NATURE

Talins and kindlins: partners in integrin-mediated adhesion

(2013) David A. Calderwood et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of Small GTPases by GEFs, GAPs, and GDIs

(2013) Jacqueline Cherfils et al.   PHYSIOLOGICAL REVIEWS

An Adaptor Molecule Afadin Regulates Lymphangiogenesis by Modulating RhoA Activity in the Developing Mouse Embryo

(2013) Takashi Majima et al.   PLoS One

Rasip1 mediates Rap1 regulation of Rho in endothelial barrier function through ArhGAP29

(2013) A. Post et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crosstalk Between Reticular Adherens Junctions and Platelet Endothelial Cell Adhesion Molecule-1 Regulates Endothelial Barrier Function

(2012) Laura Fernández-Martín et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Anti-angiogenesis therapy in cancer: Current challenges and future perspectives

(2012) Farbod Shojaei   CANCER LETTERS

Novel insights into leukocyte extravasation

(2012) Dietmar Vestweber   CURRENT OPINION IN HEMATOLOGY

Vascular endothelial-cadherin and vascular stability

(2012) Elisabetta Dejana et al.   CURRENT OPINION IN HEMATOLOGY

Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling

(2012) Stephan Huveneers et al.   JOURNAL OF CELL BIOLOGY

Enhanced Leptin Sensitivity, Reduced Adiposity, and Improved Glucose Homeostasis in Mice Lacking Exchange Protein Directly Activated by Cyclic AMP Isoform 1

(2012) J. Yan et al.   MOLECULAR AND CELLULAR BIOLOGY

Hypoxia—a key regulator of angiogenesis and inflammation in rheumatoid arthritis

(2012) Sofia Konisti et al.   Nature Reviews Rheumatology

Developmental and Pathological Angiogenesis

(2011) Alicia S. Chung et al.   Annual Review of Cell and Developmental Biology

Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin  v 3

(2011) S. Lakshmikanthan et al.   BLOOD

Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

(2011) Willem-Jan Pannekoek et al.   CELLULAR SIGNALLING

Blood Vessel Tubulogenesis Requires Rasip1 Regulation of GTPase Signaling

(2011) Ke Xu et al.   DEVELOPMENTAL CELL

Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability

(2011) Dörte Schulte et al.   EMBO JOURNAL

The cytoskeletal mechanisms of cell–cell junction formation in endothelial cells

(2011) Matthew K. Hoelzle et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Adherens junctions connect stress fibers between adjacent endothelial cells

(2010) Jaime Millan et al.   BMC BIOLOGY

Role of Afadin in Vascular Endothelial Growth Factor– and Sphingosine 1-Phosphate–Induced Angiogenesis

(2010) Hideto Tawa et al.   CIRCULATION RESEARCH

Rap1, a mercenary among the Ras-like GTPases

(2010) E.W. Frische et al.   DEVELOPMENTAL BIOLOGY

CCM1 regulates vascular-lumen organization by inducing endothelial polarity

(2010) M. G. Lampugnani et al.   JOURNAL OF CELL SCIENCE

Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity

(2010) Rebecca A. Stockton et al.   JOURNAL OF EXPERIMENTAL MEDICINE

α-Catenin as a tension transducer that induces adherens junction development

(2010) Shigenobu Yonemura et al.   NATURE CELL BIOLOGY

Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens

(2010) Michael Smutny et al.   NATURE CELL BIOLOGY

Regulation of angiogenesis by a small GTPase Rap1

(2010) Magdalena Chrzanowska-Wodnicka   VASCULAR PHARMACOLOGY

Rasip1 is required for endothelial cell motility, angiogenesis and vessel formation

(2009) Ke Xu et al.   DEVELOPMENTAL BIOLOGY

The Molecular Basis of Vascular Lumen Formation in the Developing Mouse Aorta

(2009) Boris Strilić et al.   DEVELOPMENTAL CELL

The Control of Vascular Integrity by Endothelial Cell Junctions: Molecular Basis and Pathological Implications

(2009) Elisabetta Dejana et al.   DEVELOPMENTAL CELL

Hereditary haemorrhagic telangiectasia: a clinical and scientific review

(2009) Fatima S Govani et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Structure and Biochemistry of Cadherins and Catenins

(2009) L. Shapiro et al.   Cold Spring Harbor Perspectives in Biology

The Immunoglobulin-Like Cell Adhesion Molecule Nectin and Its Associated Protein Afadin

(2008) Yoshimi Takai et al.   Annual Review of Cell and Developmental Biology

Cell–cell junction formation: The role of Rap1 and Rap1 guanine nucleotide exchange factors

(2008) Willem-Jan Pannekoek et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis

(2008) G. Carmona et al.   BLOOD

Rap1a Is a Key Regulator of Fibroblast Growth Factor 2-Induced Angiogenesis and Together with Rap1b Controls Human Endothelial Cell Functions

(2008) J. Yan et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of Epac1, an Exchange Factor for Rap GTPases, in Endothelial Microtubule Dynamics and Barrier Function

(2008) Seema Sehrawat et al.   MOLECULAR BIOLOGY OF THE CELL

Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation

(2008) Yoshimi Takai et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY