Organocatalytic strategies for enantioselective metal-free reductions

Stereoselective Lewis Base-Catalyzed Asymmetric Hydrosilylation of α-Acetamido-β-enamino Esters: Straightforward Approach for the Construction of α,β-Diamino Acid Derivatives

(2013) Yan Jiang et al.   ADVANCED SYNTHESIS & CATALYSIS

Chemo- and Enantioselective Brønsted Acid-Catalyzed Reduction of α-Imino Esters with Catecholborane

(2013) Dieter Enders et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective reduction of ketoimines promoted by easily available (S)-proline derivatives

(2013) Martina Bonsignore et al.   Beilstein Journal of Organic Chemistry

Stereoselective metal-free catalytic synthesis of chiral trifluoromethyl aryl and alkyl amines

(2013) Andrea Genoni et al.   CHEMICAL COMMUNICATIONS

Pharmaceutical Green Chemistry process changes – how long does it take to obtain regulatory approval?

(2013) Peter J. Dunn   GREEN CHEMISTRY

An Organocatalyst Bearing Stereogenic Carbon and Sulfur Centers as an Efficient Promoter for Enantioselective Hydrosilylation of 1,4-Benzooxazines

(2013) Xiang-Wei Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Chiral Dienes as “Ligands” for Borane-Catalyzed Metal-Free Asymmetric Hydrogenation of Imines

(2013) Yongbing Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Phosphoric Acid-Catalyzed Oxidative Kinetic Resolution of Indolines Based on Transfer Hydrogenation to Imines

(2013) Kodai Saito et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Synthesis of Tetrahydro-β-carbolines via Chiral Phosphoric Acid Catalyzed Transfer Hydrogenation Reaction

(2013) Qin Yin et al.   ORGANIC LETTERS

Frustrated Lewis Pair Catalyzed Hydrogenations

(2013) Jan Paradies   SYNLETT

Asymmetric Ion-Pairing Catalysis

(2012) Katrien Brak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Counteranion-Directed Catalysis: Concept, Definition, and Applications

(2012) Manuel Mahlau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transfer hydrogenation with Hantzsch esters and related organic hydride donors

(2012) Chao Zheng et al.   CHEMICAL SOCIETY REVIEWS

Applications of asymmetric organocatalysis in medicinal chemistry

(2012) José Alemán et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective Hydrosilylation with Chiral Frustrated Lewis Pairs

(2012) Dianjun Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric hydrogenation of imines with a recyclable chiral frustrated Lewis pair catalyst

(2012) Ghazi Ghattas et al.   DALTON TRANSACTIONS

New Insights into Frustrated Lewis Pairs: Structural Investigations of Intramolecular Phosphane–Borane Adducts by Using Modern Solid-State NMR Techniques and DFT Calculations

(2012) Thomas Wiegand et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal-Free Aromatic Hydrogenation: Aniline to Cyclohexyl-amine Derivatives

(2012) Tayseer Mahdi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric organocatalytic reduction of ketimines with catecholborane employing a N-triflyl phosphoramide Brønsted acid as catalyst

(2012) Dieter Enders et al.   TETRAHEDRON LETTERS

Brønsted-Acid-Catalyzed Asymmetric Multicomponent Reactions for the Facile Synthesis of Highly Enantioenriched Structurally Diverse Nitrogenous Heterocycles

(2011) Jie Yu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Highly Active Metal-Free Catalysts for Hydrogenation of Unsaturated Nitrogen-Containing Compounds

(2011) Victor Sumerin et al.   ADVANCED SYNTHESIS & CATALYSIS

The Growing Impact of Catalysis in the Pharmaceutical Industry

(2011) Carl A. Busacca et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Reduction of Ketones by Phosphoric Acid Derived Catalysts

(2011) Zuhui Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Diastereoselective and Enantioselective Synthesis of α-Hydroxy β-Amino Acid Derivatives: Lewis Base Catalyzed Hydrosilylation of α-Acetoxy β-Enamino Esters

(2011) Yan Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Asymmetric Hydrosilylation of Indoles: Combined Lewis Base and Brønsted Acid Activation

(2011) You-Cai Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Lewis Base Catalyzed Highly Enantioselective Reduction of N-Alkyl β-Enamino Esters with Trichlorosilane and Water

(2011) Xinjun Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Advances in catalytic metal-free reductions: from bio-inspired concepts to applications in the organocatalytic synthesis of pharmaceuticals and natural products

(2011) Magnus Rueping et al.   GREEN CHEMISTRY

Enantioselective Synthesis of 4-Substituted 4,5-Dihydro-1H-[1,5]benzodiazepin-2(3H)-ones by the Lewis Base-Catalyzed Hydrosilylation

(2011) Xing Chen et al.   JOURNAL OF ORGANIC CHEMISTRY

Trichlorosilane mediated asymmetric reductions of the CN bond

(2011) Simon Jones et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Organocatalytic asymmetric transfer hydrogenation of imines

(2011) Johannes G. de Vries et al.   Catalysis Science & Technology

First Highly Enantioselective Synthesis of Benzodiazepinones by Catalytic Hydrogenation

(2010) Magnus Rueping et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis and Application of Polymer-Supported Chiral Brønsted Acid Organocatalysts

(2010) Magnus Rueping et al.   ADVANCED SYNTHESIS & CATALYSIS

Chiral Amine Synthesis - Recent Developments and Trends for Enamide Reduction, Reductive Amination, and Imine Reduction

(2010) Thomas C. Nugent et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric Reductive Amination of α-Branched Ketones

(2010) Vijay N. Wakchaure et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Hydrogenation with Chiral Frustrated Lewis Pairs

(2010) Dianjun Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Mechanism of Dihydrogen Activation by Frustrated Lewis Pairs Revisited

(2010) Stefan Grimme et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-free reductions of N-heterocycles via Lewis acid catalyzed hydrogenation

(2010) Stephen J. Geier et al.   CHEMICAL COMMUNICATIONS

Activation of dihydrogen by non-metal systems

(2010) Douglas W. Stephan   CHEMICAL COMMUNICATIONS

Synthesis and Structural Aspects ofN-Triflylphosphoramides and Their Calcium Salts-Highly Acidic and Effective Brønsted Acids

(2010) Magnus Rueping et al.   CHEMISTRY-A EUROPEAN JOURNAL

Trichlorosilane-Mediated Stereoselective Reduction of C=N Bonds

(2010) Stefania Guizzetti et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Chiral phosphine oxides in present-day organocatalysis

(2010) Maurizio Benaglia et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Triclorosilane-mediated stereoselective synthesis of β-amino esters and their conversion to highly enantiomerically enriched β-lactams

(2010) Stefania Guizzetti et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cycloaddition of homochiral dihydroimidazoles: A 1,3-dipolar cycloaddition route to optically active pyrrolo[1,2-a]imidazoles

(2010) Raymond C. F. Jones et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric Synthesis of Indolines by Catalytic Enantioselective Reduction of 3H-Indoles

(2010) Magnus Rueping et al.   ORGANIC LETTERS

Chiral Phosphoric Acid-Catalyzed Enantioselective Transfer Hydrogenation ofortho-Hydroxyaryl Alkyl N−H Ketimines

(2010) Thanh Binh Nguyen et al.   ORGANIC LETTERS

Chiral Phosphoric Acids as Versatile Catalysts for Enantioselective Transformations

(2010) Masahiro Terada   SYNTHESIS-STUTTGART

Frustrated Lewis Pairs: Metal-free Hydrogen Activation and More

(2009) Douglas W. Stephan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic kinetic asymmetric transfer hydrogenation of racemic 2,4-diaryl-2,3-dihydrobenzo[b][1,4]diazepines catalyzed by chiral phosphoric acids

(2009) Zhi-Yong Han et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1,1′-Binaphthyldiamine-Based Lewis Bases as Readily Available and Efficient Organocatalysts for the Reduction ofN-Aryl andN-Alkyl Ketimines

(2009) Stefania Guizzetti et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The First Highly Enantioselective Lewis Base Organocatalyzed Hydrosilylation of α-Imino Esters

(2009) Zhou-Yang Xue et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Reduction of Imines with Trichlorosilane, Catalyzed by Sigamide, an Amino Acid-Derived Formamide: Scope and Limitations†

(2009) Andrei V. Malkov et al.   JOURNAL OF ORGANIC CHEMISTRY

On the Mechanism of B(C6F5)3-Catalyzed Direct Hydrogenation of Imines: Inherent and Thermally Induced Frustration

(2009) Tibor András Rokob et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalysts immobilised onto gold nanoparticles: application in the asymmetric reduction of imines with trichlorosilane

(2009) Andrei V. Malkov et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Dendron-anchored organocatalysts: the asymmetric reduction of imines with trichlorosilane, catalysed by an amino acid-derived formamide appended to a dendron

(2009) Marek Figlus et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Stereoselective Metal-Free Catalytic Reduction of Imines: An Easy Entry to Enantiomerically Pure Amines and Natural and Unnatural α-Amino Esters

(2009) Stefania Guizzetti et al.   ORGANIC LETTERS

Highly Enantioselective Hydrogenation of Enamides Catalyzed by Chiral Phosphoric Acids

(2009) Guilong Li et al.   ORGANIC LETTERS

Chiral Lewis base promoted trichlorosilane reduction of ketimines. An enantioselective organocatalytic synthesis of chiral amines

(2009) Stefania Guizzetti et al.   TETRAHEDRON

Asymmetric Counterion Pair Catalysis: An Enantioselective Brønsted Acid-Catalyzed Protonation

(2008) Magnus Rueping et al.   ADVANCED SYNTHESIS & CATALYSIS

Rationally-DesignedS-Chiral Bissulfinamides as Highly Enantioselective Organocatalysts for Reduction of Ketimines

(2008) Dong Pei et al.   ADVANCED SYNTHESIS & CATALYSIS

Lewis Base Catalysis in Organic Synthesis

(2008) Scott E. Denmark et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lewis base-catalyzed conjugate reduction and reductive aldol reaction of α,β-unsaturated ketones using trichlorosilane

(2008) Masaharu Sugiura et al.   CHEMICAL COMMUNICATIONS

Lewis acid-catalyzed hydrogenation: B(C6F5)3-mediated reduction of imines and nitriles with H2

(2008) Preston A. Chase et al.   CHEMICAL COMMUNICATIONS

Metal-free catalytic hydrogenation of imines with tris(perfluorophenyl)borane

(2008) Dianjun Chen et al.   CHEMICAL COMMUNICATIONS

Phosphoric Acid Catalyzed Enantioselective Transfer Hydrogenation of Imines: A Density Functional Theory Study of Reaction Mechanism and the Origins of Enantioselectivity

(2008) Tommaso Marcelli et al.   CHEMISTRY-A EUROPEAN JOURNAL

Dynamic Kinetic Resolution in the Asymmetric Synthesis of β-Amino Acids by Organocatalytic Reduction of Enamines with Trichlorosilane

(2008) Andrei V. Malkov et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Enantioselective Synthesis of β-Amino Acid Derivatives by the Lewis Base Catalyzed Hydrosilylation of β-Enamino Esters

(2008) Hong-Jie Zheng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Polymer-Supported Organocatalysts: Asymmetric Reduction of Imines with Trichlorosilane Catalyzed by an Amino Acid-Derived Formamide Anchored to a Polymer†

(2008) Andrei V. Malkov et al.   JOURNAL OF ORGANIC CHEMISTRY

Theoretical Study of the Mechanism of Hantzsch Ester Hydrogenation of Imines Catalyzed by Chiral BINOL-Phosphoric Acids

(2008) Luis Simón et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric reduction of ketimines with trichlorosilane employing an imidazole derived organocatalyst

(2008) François-Moana Gautier et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Stereoselective reactions involving hypervalent silicate complexes

(2007) Maurizio Benaglia et al.   COORDINATION CHEMISTRY REVIEWS