Nuclear Nestin deficiency drives tumor senescence via lamin A/C-dependent nuclear deformation

Nestin-expressing progenitor cells: function, identity and therapeutic implications

(2018) Aurora Bernal et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Senescence and aging: Causes, consequences, and therapeutic avenues

(2017) Domhnall McHugh et al.   JOURNAL OF CELL BIOLOGY

Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability

(2017) Tohru Takaki et al.   Nature Communications

CRISPR/Cas9 in Genome Editing and Beyond

(2016) Haifeng Wang et al.   Annual Review of Biochemistry

Nestin Mediates Hedgehog Pathway Tumorigenesis

(2016) Peng Li et al.   CANCER RESEARCH

Keratins Are Going Nuclear

(2016) Ryan P. Hobbs et al.   DEVELOPMENTAL CELL

A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha

(2016) Kevin Gesson et al.   GENOME RESEARCH

Nestin Expression Is Associated with Poor Clinicopathological Features and Prognosis in Glioma Patients: an Association Study and Meta-analysis

(2016) Donglai Lv et al.   MOLECULAR NEUROBIOLOGY

Lamins: Nuclear Intermediate Filament Proteins with Fundamental Functions in Nuclear Mechanics and Genome Regulation

(2015) Yosef Gruenbaum et al.   Annual Review of Biochemistry

Nestin+ kidney resident mesenchymal stem cells for the treatment of acute kidney ischemia injury

(2015) Mei Hua Jiang et al.   BIOMATERIALS

Inhibition of nestin suppresses stem cell phenotype of glioblastomas through the alteration of post-translational modification of heat shock protein HSPA8/HSC71

(2015) Yoko Matsuda et al.   CANCER LETTERS

Keratin-17 Promotes p27KIP1 Nuclear Export and Degradation and Offers Potential Prognostic Utility

(2015) L. F. Escobar-Hoyos et al.   CANCER RESEARCH

Nestin as a marker of cancer stem cells

(2015) Jakub Neradil et al.   CANCER SCIENCE

From hair to heart: nestin-expressing hair-follicle-associated pluripotent (HAP) stem cells differentiate to beating cardiac muscle cells

(2015) Masateru Yashiro et al.   CELL CYCLE

AKT1-mediated Lamin A/C degradation is required for nuclear degradation and normal epidermal terminal differentiation

(2015) A S Naeem et al.   CELL DEATH AND DIFFERENTIATION

Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes

(2015) Ryan P Hobbs et al.   NATURE GENETICS

Nestin regulates proliferation and invasion of gastrointestinal stromal tumor cells by altering mitochondrial dynamics

(2015) J Wang et al.   ONCOGENE

Characterization of Nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunction

(2014) Mei Hua Jiang et al.   CELL RESEARCH

Nestin regulates prostate cancer cell invasion by influencing the localisation and functions of FAK and integrins

(2014) Claire L. Hyder et al.   JOURNAL OF CELL SCIENCE

Interphase phosphorylation of lamin A

(2014) V. Kochin et al.   JOURNAL OF CELL SCIENCE

Post-translational modifications of intermediate filament proteins: mechanisms and functions

(2014) Natasha T. Snider et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of the Stem Cell-Associated Intermediate Filament Nestin in Malignant Proliferation of Non-Small Cell Lung Cancer

(2014) Zhenguang Chen et al.   PLoS One

Chemical Inhibition of NAT10 Corrects Defects of Laminopathic Cells

(2014) D. Larrieu et al.   SCIENCE

The protein kinase Akt/PKB regulates both prelamin A degradation and Lmna gene expression

(2013) Jessika Bertacchini et al.   FASEB JOURNAL

Mechanical model of blebbing in nuclear lamin meshworks

(2013) Chloe M. Funkhouser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative stress induces an ATM-independent senescence pathway through p38 MAPK-mediated lamin B1 accumulation

(2012) Aurelia Barascu et al.   EMBO JOURNAL

Nuclear envelope dispersion triggered by deregulated Cdk5 precedes neuronal death

(2011) Kuei-Hua Chang et al.   MOLECULAR BIOLOGY OF THE CELL

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

Proliferation of Immature Tumor Vessels Is a Novel Marker of Clinical Progression in Prostate Cancer

(2009) K. Gravdal et al.   CANCER RESEARCH

The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription

(2008) T. Shimi et al.   GENES & DEVELOPMENT

Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope

(2008) José María González et al.   JOURNAL OF CELL BIOLOGY