Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells
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Title
Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells
Authors
Keywords
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Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature America, Inc
Online
2018-08-24
DOI
10.1038/s41467-018-06021-7
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Note: Only part of the references are listed.- Tracing the origins of relapse in acute myeloid leukaemia to stem cells
- (2017) Liran I. Shlush et al. NATURE
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- (2016) M. Mossner et al. BLOOD
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- (2016) Jeffrey M. Bernitz et al. CELL
- Loss-of-function mutations of Dynamin 2 promote T-ALL by enhancing IL-7 signalling
- (2016) C S Tremblay et al. LEUKEMIA
- The LMO2 oncogene regulates DNA replication in hematopoietic cells
- (2016) Marie-Claude Sincennes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
- (2015) D. P. Steensma et al. BLOOD
- Clonal evolution of preleukemic hematopoietic stem cells in acute myeloid leukemia
- (2015) Stephen M. Sykes et al. EXPERIMENTAL HEMATOLOGY
- Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia
- (2015) Jeffery M. Klco et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Asymmetric cell division during T cell development controls downstream fate
- (2015) Kim Pham et al. JOURNAL OF CELL BIOLOGY
- Acute myeloid leukemia ontogeny is defined by distinct somatic mutations
- (2014) R. C. Lindsley et al. BLOOD
- Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons
- (2014) Eric M. Pietras et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Hhex regulates Kit to promote radioresistance of self-renewing thymocytes in Lmo2-transgenic mice
- (2014) B J Shields et al. LEUKEMIA
- Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
- (2014) Liran I. Shlush et al. NATURE
- SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells
- (2014) Bastien Gerby et al. PLoS Genetics
- Divisional History and Hematopoietic Stem Cell Function during Homeostasis
- (2014) Jiajing Qiu et al. Stem Cell Reports
- Requirement for Lyl1 in a model of Lmo2-driven early T-cell precursor ALL
- (2013) M. P. McCormack et al. BLOOD
- TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy
- (2013) Fabienne Brenet et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Maintenance of the hematopoietic stem cell pool in bone marrow niches by EVI1-regulated GPR56
- (2013) Y Saito et al. LEUKEMIA
- Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness
- (2013) Qing Li et al. NATURE
- DNA damage in stem cells activates p21, inhibits p53, and induces symmetric self-renewing divisions
- (2013) A. Insinga et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Concise Review: Preleukemic Stem Cells: Molecular Biology and Clinical Implications of the Precursors to Leukemia Stem Cells
- (2013) Ashley Pandolfi et al. Stem Cells Translational Medicine
- Pharmacokinetic Modeling of an Induction Regimen for In Vivo Combined Testing of Novel Drugs against Pediatric Acute Lymphoblastic Leukemia Xenografts
- (2012) Barbara Szymanska et al. PLoS One
- The endocytic adaptor Numb regulates thymus size by modulating pre-TCR signaling during asymmetric division
- (2010) R. Aguado et al. BLOOD
- IL-7 induces rapid clathrin-mediated internalization and JAK3-dependent degradation of IL-7R in T cells
- (2010) C. M. Henriques et al. BLOOD
- The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression
- (2010) Piu Wong et al. CANCER RESEARCH
- A Distinctive DNA Damage Response in Human Hematopoietic Stem Cells Reveals an Apoptosis-Independent Role for p53 in Self-Renewal
- (2010) Michael Milyavsky et al. Cell Stem Cell
- Hematopoietic Stem Cell Quiescence Promotes Error-Prone DNA Repair and Mutagenesis
- (2010) Mary Mohrin et al. Cell Stem Cell
- Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes
- (2010) M. Tremblay et al. GENES & DEVELOPMENT
- Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia
- (2010) Letetia Jones et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The TLX1 oncogene drives aneuploidy in T cell transformation
- (2010) Kim De Keersmaecker et al. NATURE MEDICINE
- The Lmo2 Oncogene Initiates Leukemia in Mice by Inducing Thymocyte Self-Renewal
- (2010) M. P. McCormack et al. SCIENCE
- Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer
- (2009) R. A. Neumuller et al. GENES & DEVELOPMENT
- Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells
- (2009) Andrea Viale et al. NATURE
- Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair
- (2008) Anne Wilson et al. CELL
- Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells
- (2008) Adlen Foudi et al. NATURE BIOTECHNOLOGY
- Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia
- (2008) C. G. Mullighan et al. SCIENCE
- Aneuploidy Affects Proliferation and Spontaneous Immortalization in Mammalian Cells
- (2008) B. R. Williams et al. SCIENCE
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