Molecular mechanisms of hepatic apoptosis

Characteristics of patients dying from acute viral hepatitis in Serbia

(2016) Neda SVIRTLIH et al.   Turkish Journal of Gastroenterology

The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARα; and repressed by C/EBPα: Implications in FABP1 down-regulation in nonalcoholic fatty liver disease

(2013) Carla Guzmán et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Epidemiology and Natural History of Patients with NAFLD

(2013) Neeraj Bhala et al.   CURRENT PHARMACEUTICAL DESIGN

Incidence, Presentation, and Outcomes in Patients With Drug-Induced Liver Injury in the General Population of Iceland

(2013) Einar S. Björnsson et al.   GASTROENTEROLOGY

Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis

(2013) Lars P. Bechmann et al.   HEPATOLOGY

Drug-induced acute liver injury mimicking autoimmune hepatitis after intake of dietary supplements containing glucosamine and chondroitin sulfate

(2013) Johann von Felden et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Expression of genes for microRNA-processing enzymes is altered in advanced non-alcoholic fatty liver disease

(2013) Haveesh Sharma et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Hepatitis C Virus Envelope Glycoprotein Signatures Are Associated With Treatment Failure and Modulation of Viral Entry and Neutralization

(2013) Evelyne Schvoerer et al.   JOURNAL OF INFECTIOUS DISEASES

Toll Like Receptor 3 Plays a Critical Role in the Progression and Severity of Acetaminophen-Induced Hepatotoxicity

(2013) Karen A. Cavassani et al.   PLoS One

Epigenetic Regulation of miR-34a Expression in Alcoholic Liver Injury

(2012) Fanyin Meng et al.   AMERICAN JOURNAL OF PATHOLOGY

Effectors of alcohol-induced cell killing in Drosophila

(2012) P Chen et al.   CELL DEATH AND DIFFERENTIATION

TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation

(2012) S Jouan-Lanhouet et al.   CELL DEATH AND DIFFERENTIATION

Long-term Management of Alcoholic Liver Disease

(2012) Garmen A. Woo et al.   Clinics in Liver Disease

Adiponectin: Key Player in the Adipose Tissue-Liver Crosstalk

(2012) A. R. Moschen et al.   CURRENT MEDICINAL CHEMISTRY

Evaluation of inflammatory and angiogenic factors in patients with non-alcoholic fatty liver disease

(2012) Stephanie Coulon et al.   CYTOKINE

The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans

(2012) Fadila Benhamed et al.   JOURNAL OF CLINICAL INVESTIGATION

Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell–mediated deletion

(2012) Dimitra Peppa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease

(2012) Rui E. Castro et al.   JOURNAL OF HEPATOLOGY

Activation of FoxO3a/Bim axis in patients with Primary Biliary Cirrhosis

(2012) Justyna Kopycinska et al.   LIVER INTERNATIONAL

MicroRNAs in metabolism and metabolic disorders

(2012) Veerle Rottiers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Insulin Resistance, Ceramide Accumulation, and Endoplasmic Reticulum Stress in Human Chronic Alcohol-Related Liver Disease

(2012) Lisa Longato et al.   Oxidative Medicine and Cellular Longevity

TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner

(2012) A Badmann et al.   Cell Death & Disease

Role of NKT cells in autoimmune liver disease

(2011) Tania Santodomingo-Garzon et al.   AUTOIMMUNITY REVIEWS

Pathophysiologic role of hepatocyte nuclear factor 6

(2011) Kewei Wang et al.   CELLULAR SIGNALLING

Ursodeoxycholic acid in cholestasis: linking action mechanisms to therapeutic applications

(2011) Marcelo G. Roma et al.   CLINICAL SCIENCE

A novel agonist of PPAR-γ based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance

(2011) Hao Zheng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Loss of Caspase-8 Protects Mice Against Inflammation-Related Hepatocarcinogenesis but Induces Non-Apoptotic Liver Injury

(2011) Christian Liedtke et al.   GASTROENTEROLOGY

A phase 2, randomized, double-blind, placebo-controlled study of GS-9450 in subjects with nonalcoholic steatohepatitis

(2011) Vlad Ratziu et al.   HEPATOLOGY

Galectin-3 deficiency prevents concanavalin A-induced hepatitis in mice

(2011) Vladislav Volarevic et al.   HEPATOLOGY

Ablation of c-FLIP in hepatocytes enhances death-receptor mediated apoptosis and toxic liver injury in vivo

(2011) Jörn M. Schattenberg et al.   JOURNAL OF HEPATOLOGY

A role for miR-296 in the regulation of lipoapoptosis by targeting PUMA

(2011) Sophie C. Cazanave et al.   JOURNAL OF LIPID RESEARCH

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

(2011) William J. Kaiser et al.   NATURE

Circulating MicroRNAs in Patients with Chronic Hepatitis C and Non-Alcoholic Fatty Liver Disease

(2011) Silvia Cermelli et al.   PLoS One

Hepatitis viruses: Not always what it seems to be

(2011) JUAN FERNANDO GALLEGOS-OROZCO et al.   REVISTA MEDICA DE CHILE

Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage

(2011) A Badmann et al.   Cell Death & Disease

Genetic variation in APOJ, LPL, and TNFRSF10B affects plasma fatty acid distribution in Alaskan Eskimos

(2010) V Saroja Voruganti et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Obesity Affects the Liver – The Link between Adipocytes and Hepatocytes

(2010) Alexander Wree et al.   DIGESTION

Biliary intervention aggravates cholestatic liver injury, and induces hepatic inflammation, proliferation and fibrogenesis in BDL mice

(2010) Yang-An Wen et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Mitochondrial superoxide dismutase and glutathione peroxidase in idiosyncratic drug-induced liver injury

(2010) M. Isabel Lucena et al.   HEPATOLOGY

The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function

(2010) Bijan Raziorrouh et al.   HEPATOLOGY

The autoimmunity of primary biliary cirrhosis and the clonal selection theory

(2010) Carlo Selmi et al.   IMMUNOLOGY AND CELL BIOLOGY

Intracellular Nicotinamide Phosphoribosyltransferase Protects against Hepatocyte Apoptosis and Is Down-Regulated in Nonalcoholic Fatty Liver Disease

(2010) Tuva B. Dahl et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

In PSC with dominant bile duct stenosis, IBD is associated with an increase of carcinomas and reduced survival

(2010) Gerda Rudolph et al.   JOURNAL OF HEPATOLOGY

Apoptosis markers related to pathogenesis of pediatric chronic hepatitis C virus infection: M30 mirrors the severity of steatosis

(2010) Pamela Valva et al.   JOURNAL OF MEDICAL VIROLOGY

Splicing Diversity of the Human OCLN Gene and Its Biological Significance for Hepatitis C Virus Entry

(2010) I. Kohaar et al.   JOURNAL OF VIROLOGY

Genomic indicators in the blood predict drug-induced liver injury

(2010) J Huang et al.   PHARMACOGENOMICS JOURNAL

Estrés oxidativo hepatocitario y hepatopatía alcohólica

(2010) L. Conde de la Rosa et al.   REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS

Oxidative stress and hepatic stellate cell activation are key events in arsenic induced liver fibrosis in mice

(2010) Subhadip Ghatak et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Targeting HCV Entry For Development of Therapeutics

(2010) Flossie Wong-Staal et al.   Viruses-Basel

Early transcriptional deregulation of hepatic mitochondrial biogenesis and its consequent effects on murine cholestatic liver injury

(2009) Mao-Meng Tiao et al.   APOPTOSIS

Putative roles of hepatitis B x antigen in the pathogenesis of chronic liver disease

(2009) Mark A. Feitelson et al.   CANCER LETTERS

Definition and natural history of metabolic steatosis: clinical aspects of NAFLD, NASH and cirrhosis

(2009) L. Serfaty et al.   DIABETES & METABOLISM

Immune-mediated liver diseases: programmed cell death ligands and circulating apoptotic markers

(2009) Andreas E Kremer et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver

(2009) Hayato Hikita et al.   HEPATOLOGY

CpG ODN pretreatment attenuates concanavalin A-induced hepatitis in mice

(2009) Hui Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Genetic variation inCLDN1and susceptibility to hepatitis C virus infection

(2009) V. Bekker et al.   JOURNAL OF VIRAL HEPATITIS

Enhanced PD-1 Expression by T Cells in Cerebrospinal Fluid Does Not Reflect Functional Exhaustion during Chronic Human Immunodeficiency Virus Type 1 Infection

(2009) S. Sadagopal et al.   JOURNAL OF VIROLOGY

Reversibility of fibrosis, inflammation, and endoplasmic reticulum stress in the liver of rats fed a methionine–choline-deficient diet

(2009) Yong-ping Mu et al.   LABORATORY INVESTIGATION

The Fas–FADD death domain complex structure unravels signalling by receptor clustering

(2009) Fiona L. Scott et al.   NATURE

Human occludin is a hepatitis C virus entry factor required for infection of mouse cells

(2009) Alexander Ploss et al.   NATURE

Progressive familial intrahepatic cholestasis

(2009) Anne Davit-Spraul et al.   Orphanet Journal of Rare Diseases

Protective effect of bicyclol on tetracycline-induced fatty liver in mice

(2009) Hong-Yan Yu et al.   TOXICOLOGY

TNFα is required for cholestasis-induced liver fibrosis in the mouse

(2008) Erwin Gäbele et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hepatitis B virus core protein inhibits TRAIL-induced apoptosis of hepatocytes by blocking DR5 expression

(2008) J Du et al.   CELL DEATH AND DIFFERENTIATION

Anionic phospholipid-induced regulation of reactive oxygen species production by human cytochrome P450 2E1

(2008) Eun Yi Cho et al.   FEBS LETTERS

Portal chronic inflammation in nonalcoholic fatty liver disease (NAFLD): A histologic marker of advanced NAFLD-Clinicopathologic correlations from the nonalcoholic steatohepatitis clinical research network

(2008) Elizabeth M. Brunt et al.   HEPATOLOGY

Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes

(2008) Binje Vick et al.   HEPATOLOGY

Impaired receptor-mediated endocytosis: Its role in alcohol-induced apoptosis

(2008) Carol A Casey et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

A Predominant Role for Parenchymal c-Jun Amino Terminal Kinase (JNK) in the Regulation of Systemic Insulin Sensitivity

(2008) Sara N. Vallerie et al.   PLoS One

Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease

(2008) K. Takeda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA