Chemotherapeutic induction of mitochondrial oxidative stress activates GSK-3α/β and Bax, leading to permeability transition pore opening and tumor cell death
出版年份 2012 全文链接
标题
Chemotherapeutic induction of mitochondrial oxidative stress activates GSK-3α/β and Bax, leading to permeability transition pore opening and tumor cell death
作者
关键词
-
出版物
Cell Death & Disease
Volume 3, Issue 12, Pages e444-e444
出版商
Springer Nature
发表日期
2012-12-13
DOI
10.1038/cddis.2012.184
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Induction of the permeability transition pore in cells depleted of mitochondrial DNA
- (2012) Ionica Masgras et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- GSK-3β at the crossroads in the signalling of heart preconditioning: implication of mTOR and Wnt pathways
- (2011) François Vigneron et al. CARDIOVASCULAR RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis
- (2011) Andrea Rasola et al. CELL CALCIUM
- Intracellular zinc release-activated ERK-dependent GSK-3β–p53 and Noxa–Mcl-1 signaling are both involved in cardiac ischemic-reperfusion injury
- (2011) C-L Lin et al. CELL DEATH AND DIFFERENTIATION
- SCaMC-1 promotes cancer cell survival by desensitizing mitochondrial permeability transition via ATP/ADP-mediated matrix Ca2+ buffering
- (2011) J Traba et al. CELL DEATH AND DIFFERENTIATION
- Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
- (2011) Gina M. DeNicola et al. NATURE
- Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress
- (2011) A. T. Shaw et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
- (2011) D. Anastasiou et al. SCIENCE
- BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial pore
- (2011) Loren D. Walensky et al. TRENDS IN BIOCHEMICAL SCIENCES
- GSK-3: Functional Insights from Cell Biology and Animal Models
- (2011) Oksana Kaidanovich-Beilin et al. Frontiers in Molecular Neuroscience
- Redox metabolism and malignancy
- (2010) Christina L Grek et al. CURRENT OPINION IN PHARMACOLOGY
- Signal transduction to the permeability transition pore
- (2010) Andrea Rasola et al. FEBS LETTERS
- Gold(III)-dithiocarbamato anticancer agents: Activity, toxicology and histopathological studies in rodents
- (2010) Cristina Marzano et al. INTERNATIONAL JOURNAL OF CANCER
- Antitumor activity of gold(III)-dithiocarbamato derivatives on prostate cancer cells and xenografts
- (2010) Lara Cattaruzza et al. INTERNATIONAL JOURNAL OF CANCER
- The architecture of respiratory complex I
- (2010) Rouslan G. Efremov et al. NATURE
- Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
- (2010) F. Weinberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes
- (2010) A. J. Levine et al. SCIENCE
- Mitochondrial calcium and the permeability transition in cell death
- (2009) John J. Lemasters et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Mitochondrial Complex I decrease is responsible for bioenergetic dysfunction in K-ras transformed cells
- (2009) Alessandra Baracca et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Mitochondrial Respiratory Complex I: Structure, Function and Implication in Human Diseases
- (2009) Lokendra Sharma et al. CURRENT MEDICINAL CHEMISTRY
- The Midas touch in cancer chemotherapy: from platinum- to gold-dithiocarbamato complexes
- (2009) Luca Ronconi et al. DALTON TRANSACTIONS
- Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
- (2009) Dunyaporn Trachootham et al. NATURE REVIEWS DRUG DISCOVERY
- Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition
- (2009) A. Rasola et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cadmium Toxicity toward Autophagy through ROS-Activated GSK-3β in Mesangial Cells
- (2009) Sheng-Hao Wang et al. TOXICOLOGICAL SCIENCES
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- Cancer Cell Metabolism: Warburg and Beyond
- (2008) Peggy P. Hsu et al. CELL
- Bcl-2 family proteins and cancer
- (2008) K W Yip et al. ONCOGENE
- Hexokinase II Detachment from Mitochondria Triggers Apoptosis through the Permeability Transition Pore Independent of Voltage-Dependent Anion Channels
- (2008) Federica Chiara et al. PLoS One
- Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes
- (2008) I. Szabo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondria in cancer: Not just innocent bystanders
- (2008) Christian Frezza et al. SEMINARS IN CANCER BIOLOGY
- Mitochondria and cellular oxygen sensing in the HIF pathway
- (2007) Cormac T. Taylor BIOCHEMICAL JOURNAL
- The BCL-2 protein family: opposing activities that mediate cell death
- (2007) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started