Cell Host Response to Infection with Novel Human Coronavirus EMC Predicts Potential Antivirals and Important Differences with SARS Coronavirus

Roles of p38 MAPK and JNK in TGF-β1-induced Human Alveolar Epithelial to Mesenchymal Transition

(2013) Hai-hua Chen et al.   ARCHIVES OF MEDICAL RESEARCH

Release of Severe Acute Respiratory Syndrome Coronavirus Nuclear Import Block Enhances Host Transcription in Human Lung Cells

(2013) A. C. Sims et al.   JOURNAL OF VIROLOGY

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

(2013) V. Stalin Raj et al.   NATURE

Development of PI3K inhibitors: lessons learned from early clinical trials

(2013) Jordi Rodon et al.   Nature Reviews Clinical Oncology

Human Coronavirus EMC Is Not the Same as Severe Acute Respiratory Syndrome Coronavirus

(2013) S. Perlman et al.   mBio

Efficient Replication of the Novel Human Betacoronavirus EMC on Primary Human Epithelium Highlights Its Zoonotic Potential

(2013) E. Kindler et al.   mBio

The newly emerged SARS-Like coronavirus HCoV-EMC also has an “Achilles’ heel”: current effective inhibitor targeting a 3C-like protease

(2013) Zhilin Ren et al.   Protein & Cell

Anti-inflammatory effect and selectivity profile of AS1940477, a novel and potent p38 mitogen-activated protein kinase inhibitor

(2012) Masaomi Terajima et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Emerging Role of Ubiquitination in Antiviral RIG-I Signaling

(2012) J. Maelfait et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Into the Eye of the Cytokine Storm

(2012) J. R. Tisoncik et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulation of epithelial immunity by IL-17 family cytokines

(2012) Rajita Pappu et al.   TRENDS IN IMMUNOLOGY

Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506

(2012) Javier Carbajo-Lozoya et al.   VIRUS RESEARCH

Human Coronavirus EMC Does Not Require the SARS-Coronavirus Receptor and Maintains Broad Replicative Capability in Mammalian Cell Lines

(2012) M. A. Muller et al.   mBio

Genomic Characterization of a Newly Discovered Coronavirus Associated with Acute Respiratory Distress Syndrome in Humans

(2012) S. van Boheemen et al.   mBio

Disruption of virus-host cell interactions and cell signaling pathways as an anti-viral approach against influenza virus infections

(2011) Stephan Ludwig   BIOLOGICAL CHEMISTRY

IL-17 Boosts Proinflammatory Outcome of Antiviral Response in Human Cells

(2011) Grigory Ryzhakov et al.   JOURNAL OF IMMUNOLOGY

Design and Synthesis of Inhaled p38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease

(2011) David S. Millan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evaluation of the Calu-3 cell line as a model of in vitro respiratory syncytial virus infection

(2011) Jennifer L. Harcourt et al.   JOURNAL OF VIROLOGICAL METHODS

Host Regulatory Network Response to Infection with Highly Pathogenic H5N1 Avian Influenza Virus

(2011) C. Li et al.   JOURNAL OF VIROLOGY

Discovery and Preclinical Validation of Drug Indications Using Compendia of Public Gene Expression Data

(2011) M. Sirota et al.   Science Translational Medicine

The SARS-Coronavirus-Host Interactome: Identification of Cyclophilins as Target for Pan-Coronavirus Inhibitors

(2011) Susanne Pfefferle et al.   PLoS Pathogens

Novel p38 MAPK inhibitor ML3403 has potent anti-inflammatory activity in airway smooth muscle

(2010) Lenka Munoz et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dynamic Innate Immune Responses of Human Bronchial Epithelial Cells to Severe Acute Respiratory Syndrome-Associated Coronavirus Infection

(2010) Tomoki Yoshikawa et al.   PLoS One

Gene Expression Signature-Based Screening Identifies New Broadly Effective Influenza A Antivirals

(2010) Laurence Josset et al.   PLoS One

BioMart – biological queries made easy

(2009) Damian Smedley et al.   BMC GENOMICS

Novel HIV-1 therapeutics through targeting altered host cell pathways

(2009) William Coley et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Critical Role of IL-17RA in Immunopathology of Influenza Infection

(2009) C. R. Crowe et al.   JOURNAL OF IMMUNOLOGY

Activation of the PI3K/Akt Pathway Early during Vaccinia and Cowpox Virus Infections Is Required for both Host Survival and Viral Replication

(2009) J. A. P. Soares et al.   JOURNAL OF VIROLOGY