Molecular Determinants of Severe Acute Respiratory Syndrome Coronavirus Pathogenesis and Virulence in Young and Aged Mouse Models of Human Disease

Coronaviruses

(2011) Mark R. Denison et al.   RNA Biology

Successful Vaccination Strategies That Protect Aged Mice from Lethal Challenge from Influenza Virus and Heterologous Severe Acute Respiratory Syndrome Coronavirus

(2010) T. Sheahan et al.   JOURNAL OF VIROLOGY

Transcriptomic Analysis Reveals a Mechanism for a Prefibrotic Phenotype in STAT1 Knockout Mice during Severe Acute Respiratory Syndrome Coronavirus Infection

(2010) G. A. Zornetzer et al.   JOURNAL OF VIROLOGY

Cooperative translocation enhances the unwinding of duplex DNA by SARS coronavirus helicase nsP13

(2010) Na-Ra Lee et al.   NUCLEIC ACIDS RESEARCH

SARS-CoV Pathogenesis Is Regulated by a STAT1 Dependent but a Type I, II and III Interferon Receptor Independent Mechanism

(2010) Matthew B. Frieman et al.   PLoS Pathogens

Infidelity of SARS-CoV Nsp14-Exonuclease Mutant Virus Replication Is Revealed by Complete Genome Sequencing

(2010) Lance D. Eckerle et al.   PLoS Pathogens

Nuclear Magnetic Resonance Structure of the Nucleic Acid-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein 3

(2009) P. Serrano et al.   JOURNAL OF VIROLOGY

Early Upregulation of Acute Respiratory Distress Syndrome-Associated Cytokines Promotes Lethal Disease in an Aged-Mouse Model of Severe Acute Respiratory Syndrome Coronavirus Infection

(2009) B. Rockx et al.   JOURNAL OF VIROLOGY

Severe Acute Respiratory Syndrome Coronavirus Papain-Like Protease Ubiquitin-Like Domain and Catalytic Domain Regulate Antagonism of IRF3 and NF- B Signaling

(2009) M. Frieman et al.   JOURNAL OF VIROLOGY

A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo

(2009) Craig W. Day et al.   VIROLOGY

Evasion by Stealth: Inefficient Immune Activation Underlies Poor T Cell Response and Severe Disease in SARS-CoV-Infected Mice

(2009) Jincun Zhao et al.   PLoS Pathogens

Pathways of Cross-Species Transmission of Synthetically Reconstructed Zoonotic Severe Acute Respiratory Syndrome Coronavirus

(2008) T. Sheahan et al.   JOURNAL OF VIROLOGY

Persistent Replication of Severe Acute Respiratory Syndrome Coronavirus in Human Tubular Kidney Cells Selects for Adaptive Mutations in the Membrane Protein

(2008) F. Pacciarini et al.   JOURNAL OF VIROLOGY

Structural Analysis of Major Species Barriers between Humans and Palm Civets for Severe Acute Respiratory Syndrome Coronavirus Infections

(2008) F. Li   JOURNAL OF VIROLOGY

Severe Acute Respiratory Syndrome Coronavirus nsp1 Suppresses Host Gene Expression, Including That of Type I Interferon, in Infected Cells

(2008) K. Narayanan et al.   JOURNAL OF VIROLOGY

MyD88 Is Required for Protection from Lethal Infection with a Mouse-Adapted SARS-CoV

(2008) Timothy Sheahan et al.   PLoS Pathogens

Animal models and vaccines for SARS-CoV infection

(2007) Anjeanette Roberts et al.   VIRUS RESEARCH