Determination of drug–receptor residence times by radioligand binding and functional assays: experimental strategies and physiological relevance
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Determination of drug–receptor residence times by radioligand binding and functional assays: experimental strategies and physiological relevance
Authors
Keywords
-
Journal
MedChemComm
Volume 3, Issue 6, Pages 645
Publisher
Royal Society of Chemistry (RSC)
Online
2012-02-28
DOI
10.1039/c2md20015e
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Molecular properties affecting fast dissociation from the D2 receptor
- (2011) Gary Tresadern et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Association of Candesartan vs Losartan With All-Cause Mortality in Patients With Heart Failure
- (2011) Maria Eklind-Cervenka JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Elusive equilibrium: the challenge of interpreting receptor pharmacology using calcium assays
- (2010) Steven J Charlton et al. BRITISH JOURNAL OF PHARMACOLOGY
- Estimation of the dissociation rate of unlabelled ligand-receptor complexes by a ‘two-step’ competition binding approach
- (2010) A Packeu et al. BRITISH JOURNAL OF PHARMACOLOGY
- Long-lasting target binding and rebinding as mechanisms to prolong in vivo drug action
- (2010) Georges Vauquelin et al. BRITISH JOURNAL OF PHARMACOLOGY
- Rebinding: or why drugs may act longerin vivothan expected from theirin vitrotarget residence time
- (2010) Georges Vauquelin Expert Opinion on Drug Discovery
- The dynamics of drug-target interactions: drug-target residence time and its impact on efficacy and safety
- (2010) Robert A Copeland Expert Opinion on Drug Discovery
- Binding kinetics and mechanism of action: toward the discovery and development of better and best in class drugs
- (2010) Rumin Zhang et al. Expert Opinion on Drug Discovery
- Binding properties of antagonists to Cannabinoid receptors in intact cells
- (2010) Marie Wennerberg et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- Structural Basis of Allosteric Ligand-Receptor Interactions in the Insulin/Relaxin Peptide Family
- (2009) Pierre De Meyts et al. Annals of the New York Academy of Sciences
- Molecular mechanisms for the persistent bronchodilatory effect of the β2-adrenoceptor agonist salmeterol
- (2009) A Szczuka et al. BRITISH JOURNAL OF PHARMACOLOGY
- Effects of losartan vs candesartan in reducing cardiovascular events in the primary treatment of hypertension
- (2009) S E Kjeldsen et al. JOURNAL OF HUMAN HYPERTENSION
- Analytical method for simultaneously measuring ex vivo drug receptor occupancy and dissociation rate: Application to (R)-dimethindene occupancy of central histamine H1receptors
- (2009) Siobhan Malany et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- Ligands, their receptors and … plasma membranes
- (2009) G. Vauquelin et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Cellular assays as portals to seven-transmembrane receptor-based drug discovery
- (2009) Terry P. Kenakin NATURE REVIEWS DRUG DISCOVERY
- Residence Time of Receptor−Ligand Complexes and Its Effect on Biological Function
- (2008) Peter J. Tummino et al. BIOCHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More