Rosuvastatin Reduces Neuroinflammation in the Hemorrhagic Transformation After rt-PA Treatment in a Mouse Model of Experimental Stroke

Statins Reduce Lipopolysaccharide-Induced Cytokine and Inflammatory Mediator Release in an In Vitro Model of Microglial-Like Cells

(2017) A. J. McFarland et al.   MEDIATORS OF INFLAMMATION

Bosutinib Attenuates Inflammation via Inhibiting Salt-Inducible Kinases in Experimental Model of Intracerebral Hemorrhage on Mice

(2017) Li Ma et al.   STROKE

Rosuvastatin postconditioning protects isolated hearts against ischemia-reperfusion injury: The role of radical oxygen species, PI3K-Akt-GSK-3β pathway, and mitochondrial permeability transition pore

(2016) Chun-Wei Liu et al.   Cardiovascular Therapeutics

Inadequate food and water intake determine mortality following stroke in mice

(2016) Athanasios Lourbopoulos et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Astrocytes: Key Regulators of Neuroinflammation

(2016) Emanuela Colombo et al.   TRENDS IN IMMUNOLOGY

The Neuroprotection of Liraglutide Against Ischaemia-induced Apoptosis through the Activation of the PI3K/AKT and MAPK Pathways

(2016) Huili Zhu et al.   Scientific Reports

Rosuvastatin attenuated the existing morphine tolerance in rats with L5 spinal nerve transection through inhibiting activation of astrocytes and phosphorylation of ERK42/44

(2015) Weiyan Li et al.   NEUROSCIENCE LETTERS

Neuroprotective effects of rosuvastatin against traumatic spinal cord injury in rats

(2014) Ramazan Kahveci et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Increased Blood-Brain Barrier Permeability on Perfusion Computed Tomography Predicts Hemorrhagic Transformation in Acute Ischemic Stroke

(2014) Ozlem Ozkul-Wermester et al.   EUROPEAN NEUROLOGY

Molecular Mechanisms Underlying the Effects of Statins in the Central Nervous System

(2014) Amelia McFarland et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Statins and Ischemic Stroke

(2014) J. David Spence   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

(2014) Jonathan Emberson et al.   LANCET

Hemorrhagic Transformation after Tissue Plasminogen Activator Reperfusion Therapy for Ischemic Stroke: Mechanisms, Models, and Biomarkers

(2014) Wei Wang et al.   MOLECULAR NEUROBIOLOGY

Cognitive decline and depressive symptoms in late-life are associated with statin use: evidence from a population-based study of Sardinian old people living in their own home

(2014) Antonella Mandas et al.   NEUROLOGICAL RESEARCH

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

(2014) Iris Postmus et al.   Nature Communications

Factors influencing haemorrhagic transformation in ischaemic stroke

(2013) José Álvarez-Sabín et al.   LANCET NEUROLOGY

Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation

(2013) Yichuan Xiao et al.   NATURE MEDICINE

Inflammation in intracerebral hemorrhage: From mechanisms to clinical translation

(2013) Yu Zhou et al.   PROGRESS IN NEUROBIOLOGY

Fingolimod Reduces Hemorrhagic Transformation Associated With Delayed Tissue Plasminogen Activator Treatment in a Mouse Thromboembolic Model

(2013) Francisco Campos et al.   STROKE

The predictive value of galectin-3 for mortality and cardiovascular events in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)

(2012) Lars Gullestad et al.   AMERICAN HEART JOURNAL

ERK5: Structure, regulation and function

(2012) Gopika N. Nithianandarajah-Jones et al.   CELLULAR SIGNALLING

Microglial Cell Activation is a Source of Metalloproteinase Generation during Hemorrhagic Transformation

(2012) Gregory J del Zoppo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease

(2012) Azeb Tadesse Argaw et al.   JOURNAL OF CLINICAL INVESTIGATION

Statins Reduce Amyloid β-Peptide Production by Modulating Amyloid Precursor Protein Maturation and Phosphorylation Through a Cholesterol-Independent Mechanism in Cultured Neurons

(2012) Ai Hosaka et al.   NEUROCHEMICAL RESEARCH

Blood-brain barrier, reperfusion injury, and hemorrhagic transformation in acute ischemic stroke

(2012) R. Khatri et al.   NEUROLOGY

A broad-spectrum matrix metalloproteinase inhibitor prevents hemorrhagic complications induced by tissue plasminogen activator in mice

(2012) K. Mishiro et al.   NEUROSCIENCE

Preclinical acute ischemic stroke modeling

(2011) Manik Mehra et al.   Journal of NeuroInterventional Surgery

Arginine-vasopressin V1a receptor inhibition improves neurologic outcomes following an intracerebral hemorrhagic brain injury

(2011) Anatol Manaenko et al.   NEUROCHEMISTRY INTERNATIONAL

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: A novel mechanism of action

(2010) Eugenio Barone et al.   PHARMACOLOGICAL RESEARCH

Behavioral deficits after distal focal cerebral ischemia in mice: Usefulness of adhesive removal test.

(2009) Thomas Freret et al.   BEHAVIORAL NEUROSCIENCE

Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein

(2009) Y. Suzuki et al.   BLOOD

Microglial Low-Density Lipoprotein Receptor-Related Protein 1 Mediates the Effect of Tissue-Type Plasminogen Activator on Matrix Metalloproteinase-9 Activity in the Ischemic Brain

(2009) Chen Zhang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The adhesive removal test: a sensitive method to assess sensorimotor deficits in mice

(2009) Valentine Bouet et al.   Nature Protocols

Ac-YVAD-CMK Decreases Blood–Brain Barrier Degradation by Inhibiting Caspase-1 Activation of Interleukin-1β in Intracerebral Hemorrhage Mouse Model

(2009) Bihua Wu et al.   Translational Stroke Research

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

New insights into NF-κB regulation and function

(2008) Shao-Cong Sun et al.   TRENDS IN IMMUNOLOGY