Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation

The type I IFN signature as a biomarker of preclinical rheumatoid arthritis

(2013) Joyce Lübbers et al.   ANNALS OF THE RHEUMATIC DISEASES

Immunopathogenesis of osteoarthritis

(2013) Abdul Haseeb et al.   CLINICAL IMMUNOLOGY

Identification of transcription regulatory relationships in rheumatoid arthritis and osteoarthritis

(2013) Guofeng Li et al.   CLINICAL RHEUMATOLOGY

Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer

(2013) Maria Lauda Tomasi et al.   EXPERIMENTAL CELL RESEARCH

Characterization of pathogenic human monoclonal autoantibodies against GM-CSF

(2013) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrating Genetic Association, Genetics of Gene Expression, and Single Nucleotide Polymorphism Set Analysis to Identify Susceptibility Loci for Type 2 Diabetes Mellitus

(2012) D. M. Greenawalt et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Multiple cytokines and chemokines are associated with rheumatoid arthritis-related autoimmunity in first-degree relatives without rheumatoid arthritis: Studies of the Aetiology of Rheumatoid Arthritis (SERA)

(2012) Jan M Hughes-Austin et al.   ANNALS OF THE RHEUMATIC DISEASES

Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritis

(2012) Gerd R Burmester et al.   ANNALS OF THE RHEUMATIC DISEASES

A systematic review and meta-analysis comparing complications following total joint arthroplasty for rheumatoid arthritis versus for osteoarthritis

(2012) Bheeshma Ravi et al.   ARTHRITIS AND RHEUMATISM

Protein engineering and preclinical development of a GM-CSF receptor antibody for the treatment of rheumatoid arthritis

(2012) RR Minter et al.   BRITISH JOURNAL OF PHARMACOLOGY

Emerging roles of immunoproteasomes beyond MHC class I antigen processing

(2012) Frédéric Ebstein et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mavrilimumab, a human monoclonal GM-CSF receptor-α antibody for the management of rheumatoid arthritis: a novel approach to therapy

(2012) Jagdish R Nair et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Common and specific signatures of gene expression and protein–protein interactions in autoimmune diseases

(2012) T Tuller et al.   GENES AND IMMUNITY

JAK and STAT Signaling Molecules in Immunoregulation and Immune-Mediated Disease

(2012) John J. O'Shea et al.   IMMUNITY

IL-18 Upregulates the Production of Key Regulators of Osteoclastogenesis from Fibroblast-Like Synoviocytes in Rheumatoid Arthritis

(2012) Wei Zhang et al.   INFLAMMATION

Osteoarthritis and Rheumatoid Arthritis: Conservative Therapeutic Management

(2012) Jeanine Beasley   Journal of Hand Therapy

Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review

(2012) B.J.E. de Lange-Brokaar et al.   OSTEOARTHRITIS AND CARTILAGE

Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis

(2012) E. Choy   RHEUMATOLOGY

Gene expression analysis of rheumatoid arthritis synovial lining regions by cDNA microarray combined with laser microdissection: up-regulation of inflammation-associated STAT1, IRF1, CXCL9, CXCL10, and CCL5

(2012) S Yoshida et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Interferon type I signature may predict non response upon rituximab in rheumatoid arthritis patients

(2012) Hennie G Raterman et al.   ARTHRITIS RESEARCH & THERAPY

Granulocyte-macrophage colony-stimulating factor is a key mediator in experimental osteoarthritis pain and disease development

(2012) Andrew D Cook et al.   ARTHRITIS RESEARCH & THERAPY

dJun and Vri/dNFIL3 Are Major Regulators of Cardiac Aging in Drosophila

(2012) Véronique Monnier et al.   PLoS Genetics

A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model

(2011) Koichiro Abe et al.   ARTHRITIS AND RHEUMATISM

The many faces of Janus kinase

(2011) Matthew M. Seavey et al.   BIOCHEMICAL PHARMACOLOGY

JunD-mediated repression of GADD45α and γ regulates escape from cell death in prostate cancer

(2011) Luiz Fernando Zerbini et al.   CELL CYCLE

Celecoxib

(2011) Paul L. McCormack   DRUGS

NFIL3/E4BP4 controls type 2 T helper cell cytokine expression

(2011) Masaki Kashiwada et al.   EMBO JOURNAL

A Distal Enhancer inIl12bIs the Target of Transcriptional Repression by the STAT3 Pathway and Requires the Basic Leucine Zipper (B-ZIP) Protein NFIL3

(2011) Amber M. Smith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NFIL3 Is a Regulator of IL-12 p40 in Macrophages and Mucosal Immunity

(2011) T. Kobayashi et al.   JOURNAL OF IMMUNOLOGY

Off-Target Serine/Threonine Kinase 10 Inhibition by Erlotinib Enhances Lymphocytic Activity Leading to Severe Skin Disorders

(2011) N. Yamamoto et al.   MOLECULAR PHARMACOLOGY

Removing Batch Effects in Analysis of Expression Microarray Data: An Evaluation of Six Batch Adjustment Methods

(2011) Chao Chen et al.   PLoS One

HZT-501 (DUEXIS®; ibuprofen 800 mg/famotidine 26.6 mg) gastrointestinal protection in the treatment of the signs and symptoms of rheumatoid arthritis and osteoarthritis

(2011) Michael Schiff et al.   Expert Review of Gastroenterology & Hepatology

2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) D. Aletaha et al.   ANNALS OF THE RHEUMATIC DISEASES

Toward a data-driven evaluation of the 2010 American College of Rheumatology/European League Against Rheumatism criteria for rheumatoid arthritis: Is it sensible to look at levels of rheumatoid factor?

(2010) M. P. M. van der Linden et al.   ARTHRITIS AND RHEUMATISM

Radiographic measurements in the evaluation and classification of elbow joint destruction in patients with rheumatoid arthritis

(2010) Kenzo Hashizume et al.   CLINICAL RHEUMATOLOGY

The lysosome among targets of metformin: new anti-inflammatory uses for an old drug?

(2010) Thomas D Lockwood   EXPERT OPINION ON THERAPEUTIC TARGETS

Cell death in rheumatoid arthritis

(2009) Adelheid Korb et al.   APOPTOSIS

Array of hope: expression profiling identifies disease biomarkers and mechanism

(2009) Soumyaroop Bhattacharya et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Adapted Boolean network models for extracellular matrix formation

(2009) Johannes Wollbold et al.   BMC Systems Biology

CD11c as a Transcriptional Biomarker to Predict Response to Anti-TNF Monotherapy With Adalimumab in Patients With Rheumatoid Arthritis

(2009) B Stuhlmüller et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice

(2009) Thierry Touvier et al.   JOURNAL OF CLINICAL INVESTIGATION

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

(2009) Shintaro Kamizono et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peripheral Blood Expression Profiles of Bone Morphogenetic Proteins, Tumor Necrosis Factor-superfamily Molecules, and Transcription Factor Runx2 Could Be Used as Markers of the Form of Arthritis, Disease Activity, and Therapeutic Responsiveness

(2009) D. GRCEVIC et al.   JOURNAL OF RHEUMATOLOGY

Comparative Performance Analysis of 4 Different Anti-Citrullinated Protein Assays in the Diagnosis of Rheumatoid Arthritis

(2009) N. MUTLU et al.   JOURNAL OF RHEUMATOLOGY

LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation

(2009) N. V. Belkina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early and long-standing rheumatoid arthritis: distinct molecular signatures identified by gene-expression profiling in synovia

(2009) Thierry Lequerré et al.   ARTHRITIS RESEARCH & THERAPY

Transcription profiling of rheumatic diseases

(2009) Lisa GM van Baarsen et al.   ARTHRITIS RESEARCH & THERAPY

The Structure of the GM-CSF Receptor Complex Reveals a Distinct Mode of Cytokine Receptor Activation

(2008) Guido Hansen et al.   CELL

Molecular aspects of rheumatoid arthritis: role of transcription factors

(2008) Hiroshi Okamoto et al.   FEBS Journal

Flagellin and lipopolysaccharide up-regulation of IL-6 and CXCLi2 gene expression in chicken heterophils is mediated by ERK1/2-dependent activation of AP-1 and NF-κB signaling pathways

(2008) Michael H. Kogut et al.   Innate Immunity

Autoimmune reactivity against the 20S-proteasome includes immunosubunits LMP2 ( 1i), MECL1 ( 2i) and LMP7 ( 5i)

(2008) S. Scheffler et al.   RHEUMATOLOGY

Structural Biology of Shared Cytokine Receptors

(2007) Xinquan Wang et al.   Annual Review of Immunology