The lysosome among targets of metformin: new anti-inflammatory uses for an old drug?

Autophagy and acute pancreatitis: A novel autophagy theory for trypsinogen activation

(2014) Masaki Ohmuraya et al.   Autophagy

Cathepsin B Is Involved in the Trafficking of TNF- -Containing Vesicles to the Plasma Membrane in Macrophages

(2014) S.-D. Ha et al.   JOURNAL OF IMMUNOLOGY

Lipopolysaccharide Can Trigger a Cathepsin B-Dependent Programmed Death Response in Human Endothelial Cells

(2009) Jie H. Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Acute Metformin Overdose: Examining Serum pH, Lactate Level, and Metformin Concentrations in Survivors Versus Nonsurvivors: A Systematic Review of the Literature

(2009) Damon M. Dell'Aglio et al.   ANNALS OF EMERGENCY MEDICINE

The ligand environment of zinc stored in vesicles

(2009) Gerd Wellenreuther et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Direct Measurement of Cathepsin B Activity in the Cytosol of Apoptotic Cells by an Activity-Based Probe

(2009) Matthew R. Pratt et al.   CHEMISTRY & BIOLOGY

Oral Antidiabetic Agents: Anti-Atherosclerotic Properties Beyond Glucose Lowering?

(2009) N. Papanas et al.   CURRENT PHARMACEUTICAL DESIGN

Autophagy in human type 2 diabetes pancreatic beta cells

(2009) M. Masini et al.   DIABETOLOGIA

Death Receptor 5 Internalization Is Required for Lysosomal Permeabilization by TRAIL in Malignant Liver Cell Lines

(2009) Yuko Akazawa et al.   GASTROENTEROLOGY

Role of cathepsin B-mediated apoptosis in fulminant hepatic failure in mice

(2009) Bing-Zhu Yan   WORLD JOURNAL OF GASTROENTEROLOGY

Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review

(2008) G Ruiz-Irastorza et al.   ANNALS OF THE RHEUMATIC DISEASES

Albumin as a zinc carrier: properties of its high-affinity zinc-binding site

(2008) Jin Lu et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Copper, Chromium, Manganese, Iron, Nickel, and Zinc Levels in Biological Samples of Diabetes Mellitus Patients

(2008) Tasneem Gul Kazi et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Gamma-IFN-inducible-lysosomal thiol reductase modulates acidic proteases and HLA class II antigen processing in melanoma

(2008) Oliver G. Goldstein et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Intracellular zinc homeostasis and zinc signaling

(2008) Masaaki Murakami et al.   CANCER SCIENCE

Diabetes and rheumatic diseases

(2008) Todd W Burner et al.   CURRENT OPINION IN RHEUMATOLOGY

Adipose Tissue Macrophages, Low Grade Inflammation and Insulin Resistance in Human Obesity

(2008) Leonie Heilbronn et al.   CURRENT PHARMACEUTICAL DESIGN

Metformin therapy and clinical uses

(2008) John HB Scarpello et al.   Diabetes & Vascular Disease Research

Cardiovascular risk in rheumatoid arthritis: effects of anti-TNF drugs

(2008) J Avouac et al.   EXPERT OPINION ON PHARMACOTHERAPY

Autophagy: a target for therapeutic interventions in myocardial pathophysiology

(2008) Antonis Halapas et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Autocatalytic processing of procathepsin B is triggered by proenzyme activity

(2008) Jerica Rozman Pungerčar et al.   FEBS Journal

The implication of proinflammatory cytokines in type 2 diabetes

(2008) Christopher et al.   Frontiers in Bioscience-Landmark

Cystatins: Biochemical and structural properties, and medical relevance

(2008) ">Vito Turk   Frontiers in Bioscience-Landmark

Displacement of the Occluding Loop by the Parasite Protein, Chagasin, Results in Efficient Inhibition of Human Cathepsin B

(2008) Izabela Redzynia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of cathepsin B by Au(I) complexes: a kinetic and computational study

(2008) Shamila S. Gunatilleke et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Metal compounds for the treatment of parasitic diseases

(2008) Simon P. Fricker et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel

(2008) Xian-Ping Dong et al.   NATURE

Analysis of metal-binding proteins separated by non-denaturating gel electrophoresis using matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)

(2008) J. Susanne Becker et al.   TALANTA

Zinc signalling and subcellular distribution: emerging targets in type 2 diabetes

(2008) Eugenio Mocchegiani et al.   TRENDS IN MOLECULAR MEDICINE

Colloidal metallic gold is not bio-inert

(2008) C. L. Brown et al.   INFLAMMOPHARMACOLOGY

Molecular background of EPM1—Unverricht–Lundborg disease

(2007) Tarja Joensuu et al.   EPILEPSIA