A global RNA-seq-driven analysis of CHO host and production cell lines reveals distinct differential expression patterns of genes contributing to recombinant antibody glycosylation

Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: A critical review

(2015) Emanual Maverakis et al.   JOURNAL OF AUTOIMMUNITY

The Current Status and Prospects of Antibody Engineering for Therapeutic Use: Focus on Glycoengineering Technology

(2015) Rinpei Niwa et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation

(2014) Yuzhou Fan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Biosimilars: Are They Bioequivalent?

(2014) Fernando Gomollón   DIGESTIVE DISEASES

Evaluating the impact of cell culture process parameters on monoclonal antibody N-glycosylation

(2014) Marija Ivarsson et al.   JOURNAL OF BIOTECHNOLOGY

Physicochemical and Functional Comparability Between the Proposed Biosimilar Rituximab GP2013 and Originator Rituximab

(2013) Jan Visser et al.   BIODRUGS

CHO cell line specific prediction and control of recombinant monoclonal antibodyN-glycosylation

(2013) Rhian K. Grainger et al.   BIOTECHNOLOGY AND BIOENGINEERING

Obinutuzumab: First Global Approval

(2013) Fiona Cameron et al.   DRUGS

IgG-Fc N-glycosylation at Asn297 and IgA O-glycosylation in the hinge region in health and disease

(2013) Jing Xue et al.   GLYCOCONJUGATE JOURNAL

Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome

(2013) Nathan E Lewis et al.   NATURE BIOTECHNOLOGY

RNA-SeQC: RNA-seq metrics for quality control and process optimization

(2012) David S. DeLuca et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Production platforms for biotherapeutic glycoproteins. Occurrence, impact, and challenges of non-human sialylation

(2012) Darius Ghaderi et al.   Biotechnology & Genetic Engineering Reviews

Characterization and comparison of commercially available TNF receptor 2-Fc fusion protein products

(2012) Qingqiao Tan et al.   mAbs

Quantitative evaluation of fucose reducing effects in a humanized antibody on Fcγ receptor binding and antibody-dependent cell-mediated cytotoxicity activities

(2012) Shan Chung et al.   mAbs

Marketing approval of mogamulizumab

(2012) Alain Beck et al.   mAbs

Production, characterization and pharmacokinetic properties of antibodies with N-linked Mannose-5 glycans

(2012) Marcella Yu et al.   mAbs

With or Without Sugar? (A)glycosylation of Therapeutic Antibodies

(2012) Dmitrij Hristodorov et al.   MOLECULAR BIOTECHNOLOGY

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Industry and regulatory experience of the glycosylation of monoclonal antibodies

(2011) Erik K. Read et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Chinese hamster genome database: An online resource for the CHO community at www.CHOgenome.org

(2011) Stephanie Hammond et al.   BIOTECHNOLOGY AND BIOENGINEERING

Fluorescence in situ hybridization using bacterial artificial chromosome (BAC) clones for the analysis of chromosome rearrangement in Chinese hamster ovary cells

(2011) Yihua Cao et al.   METHODS

The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

(2011) Xun Xu et al.   NATURE BIOTECHNOLOGY

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

Into the unknown: expression profiling without genome sequence information in CHO by next generation sequencing

(2010) Fabian Birzele et al.   NUCLEIC ACIDS RESEARCH

Two mechanisms of the enhanced antibody-dependent cellular cytotoxicity (ADCC) efficacy of non-fucosylated therapeutic antibodies in human blood

(2009) Shigeru Iida et al.   BMC CANCER

Optimal and consistent protein glycosylation in mammalian cell culture

(2009) P. Hossler et al.   GLYCOBIOLOGY

Intraclonal Protein Expression Heterogeneity in Recombinant CHO Cells

(2009) Warren Pilbrough et al.   PLoS One

An Abundance of Ubiquitously Expressed Genes Revealed by Tissue Transcriptome Sequence Data

(2009) Daniel Ramsköld et al.   PLoS Computational Biology

Antibody fucosylation differentially impacts cytotoxicity mediated by NK and PMN effector cells

(2008) M. Peipp et al.   BLOOD

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

The N-Linked sugar chains of human immunoglobulin G: Their unique pattern, and their functional roles

(2007) Akira Kobata   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glycosylation of Recombinant Antibody Therapeutics

(2005) Royston Jefferis   BIOTECHNOLOGY PROGRESS