Centipede Venoms and Their Components: Resources for Potential Therapeutic Applications

Scolopendin 2, a cationic antimicrobial peptide from centipede, and its membrane-active mechanism

(2015) Heejeong Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Antimicrobial peptide scolopendrasin VII, derived from the centipede Scolopendra subspinipes mutilans, stimulates macrophage chemotaxis via formyl peptide receptor 1

(2015) Yoo Jung Park et al.   BMB Reports

Purification and Characterization of a New Serine Protease (VLCII) Isolated fromVipera lebetinaVenom: Its Role in Hemostasis

(2015) Kadi-Saci Amel et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

T-type calcium channel antagonists, mibefradil and NNC-55-0396 inhibit cell proliferation and induce cell apoptosis in leukemia cell lines

(2015) Weifeng Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Anticancer Activity of the Antimicrobial Peptide Scolopendrasin VII Derived from the Centipede, Scolopendra subspinipes mutilans

(2015) Joon Ha Lee et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Peptidomics combined with cDNA library unravel the diversity of centipede venom

(2015) Mingqiang Rong et al.   Journal of Proteomics

Voltage-Gated Sodium Channels as Therapeutic Targets for Treatment of Painful Diabetic Neuropathy

(2015) Shivsharan Kharatmal et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

A pain-inducing centipede toxin targets the heat activation machinery of nociceptor TRPV1

(2015) Shilong Yang et al.   Nature Communications

Three Peptide Modulators of the Human Voltage-Gated Sodium Channel 1.7, an Important Analgesic Target, from the Venom of an Australian Tarantula

(2015) Chun Chow et al.   Toxins

Centipede Venom: Recent Discoveries and Current State of Knowledge

(2015) Eivind Undheim et al.   Toxins

Comparative studies on the structure and development of the venom-delivery system of centipedes, and a hypothesis on the origin of this evolutionary novelty

(2015) Michel M. Dugon et al.   EVOLUTION & DEVELOPMENT

Interaction of the BKCachannel gating ring with dendrotoxins

(2014) Zoltan Takacs et al.   Channels

Antimicrobial peptides in the centipede Scolopendra subspinipes mutilans

(2014) Won Gi Yoo et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

Identification of a novel antimicrobial peptide, scolopendin 1, derived from centipedeScolopendra subspinipes mutilansand its antifungal mechanism

(2014) H. Choi et al.   INSECT MOLECULAR BIOLOGY

Scolopendra bites: a report of two cases and review of the literature

(2014) Stefano Veraldi et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Purification and biochemical characterization of a fibrin(ogen)olytic metalloprotease from Macrovipera mauritanica snake venom which induces vascular permeability

(2014) EUN HEE LEE et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Binding Site and Inhibitory Mechanism of the Mambalgin-2 Pain-relieving Peptide on Acid-sensing Ion Channel 1a

(2014) Miguel Salinas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isolation and characterization of SsmTx-I, a Specific Kv2.1 blocker from the venom of the centipedeScolopendra Subspinipes MutilansL. Koch

(2014) Minzhi Chen et al.   JOURNAL OF PEPTIDE SCIENCE

Clawing through Evolution: Toxin Diversification and Convergence in the Ancient Lineage Chilopoda (Centipedes)

(2014) Eivind A.B. Undheim et al.   MOLECULAR BIOLOGY AND EVOLUTION

Extracts of centipede Scolopendra subspinipes mutilans induce cell cycle arrest and apoptosis in A375 human melanoma cells

(2014) WEINA MA et al.   Oncology Letters

Isolation and Biochemical Characterization of a New Thrombin-Like Serine Protease fromBothrops pirajaiSnake Venom

(2014) Kayena D. Zaqueo et al.   Biomed Research International

Antifungal effect and pore-forming action of lactoferricin B like peptide derived from centipede Scolopendra subspinipes mutilans

(2013) Hyemin Choi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

A Novel Factor Xa-Inhibiting Peptide from Centipedes Venom

(2013) Yi Kong et al.   International Journal of Peptide Research and Therapeutics

Potent Elastase Inhibitors from Cyanobacteria: Structural Basis and Mechanisms Mediating Cytoprotective and Anti-Inflammatory Effects in Bronchial Epithelial Cells

(2013) Lilibeth A. Salvador et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antimicrobial Activity of the Synthetic Peptide Scolopendrasin II from the Centipede Scolopendra subspinipes mutilans

(2013) Young-Nam Kwon   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Dracula's children: Molecular evolution of vampire bat venom

(2013) Dolyce H.W. Low et al.   Journal of Proteomics

Discovery of a selective NaV1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models

(2013) S. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Construction and expression of an antimicrobial peptide scolopin 1 from the centipede venoms of Scolopendra subspinipes mutilans in Escherichia coli using SUMO fusion partner

(2013) Huanhuan Hou et al.   PROTEIN EXPRESSION AND PURIFICATION

Proteomic characterisation of toxins isolated from nematocysts of the South Atlantic jellyfish Olindias sambaquiensis

(2013) Andrew J. Weston et al.   TOXICON

Scorpion venom components that affect ion-channels function

(2013) V. Quintero-Hernández et al.   TOXICON

Venom Peptides as a Rich Source of Cav2.2 Channel Blockers

(2013) Silmara Sousa et al.   Toxins

Purification and characterization of a novel antithrombotic peptide from Scolopendra subspinipes mutilans

(2012) Yi Kong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Venomic and Transcriptomic Analysis of Centipede Scolopendra subspinipes dehaani

(2012) Zi-Chao Liu et al.   JOURNAL OF PROTEOME RESEARCH

Chemical Punch Packed in Venoms Makes Centipedes Excellent Predators

(2012) Shilong Yang et al.   MOLECULAR & CELLULAR PROTEOMICS

Black mamba venom peptides target acid-sensing ion channels to abolish pain

(2012) Sylvie Diochot et al.   NATURE

Antifibrinolytic Role of a Bee Venom Serine Protease Inhibitor That Acts as a Plasmin Inhibitor

(2012) Young Moo Choo et al.   PLoS One

Spider-venom peptides that target voltage-gated sodium channels: Pharmacological tools and potential therapeutic leads

(2012) Julie K. Klint et al.   TOXICON

Scorpion Toxins Specific for Potassium (K+) Channels: A Historical Overview of Peptide Bioengineering

(2012) Zachary Bergeron et al.   Toxins

“Nanoantibiotics”: A new paradigm for treating infectious diseases using nanomaterials in the antibiotics resistant era

(2011) Ae Jung Huh et al.   JOURNAL OF CONTROLLED RELEASE

Extreme diversity of scorpion venom peptides and proteins revealed by transcriptomic analysis: Implication for proteome evolution of scorpion venom arsenal

(2011) Yibao Ma et al.   Journal of Proteomics

A new chymotrypsin-like serine protease involved in dietary protein digestion in a primitive animal, Scorpio maurus: purification and biochemical characterization

(2011) Hanen Louati et al.   Lipids in Health and Disease

A Limited Role for Gene Duplications in the Evolution of Platypus Venom

(2011) E. S. W. Wong et al.   MOLECULAR BIOLOGY AND EVOLUTION

Cretaceous–Tertiary diversification among select Scolopendrid centipedes of South India

(2011) Jahnavi Joshi et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

On the venom system of centipedes (Chilopoda), a neglected group of venomous animals

(2011) Eivind A.B. Undheim et al.   TOXICON

A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain

(2010) Christopher J. Bohlen et al.   CELL

The pharmacological role of nucleotidases in snake venoms

(2010) Bhadrapura L. Dhananjaya et al.   CELL BIOCHEMISTRY AND FUNCTION

Insights into the venom composition of the ectoparasitoid waspNasonia vitripennisfrom bioinformatic and proteomic studies

(2010) D. C. de Graaf et al.   INSECT MOLECULAR BIOLOGY

Origins and Evolution of Antibiotic Resistance

(2010) J. Davies et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The Toxicogenomic Multiverse: Convergent Recruitment of Proteins Into Animal Venoms

(2009) Bryan G. Fry et al.   Annual Review of Genomics and Human Genetics

Trunk anomalies in the centipede Stigmatogaster subterranea provide insight into late-embryonic segmentation

(2009) Małgorzata Leśniewska et al.   ARTHROPOD STRUCTURE & DEVELOPMENT

The K+channels KCa3.1 and Kv1.3 as novel targets for asthma therapy

(2009) Peter Bradding et al.   BRITISH JOURNAL OF PHARMACOLOGY

Subtype-selective targeting of voltage-gated sodium channels

(2009) Steve England et al.   BRITISH JOURNAL OF PHARMACOLOGY

Serine proteases

(2009) Enrico Di Cera   IUBMB LIFE

Anti-atherogenic effects of centipede acidic protein in rats fed an atherogenic diet

(2009) Yanling Wu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Factor Xa-like and fibrin(ogen)olytic activities of a serine protease from Hippasa agelenoides spider venom gland extract

(2009) S. Devaraja et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Venom from the centipede Scolopendra viridis Say: Purification, gene cloning and phylogenetic analysis of a phospholipase A2

(2009) Lidia González-Morales et al.   TOXICON

Two novel antimicrobial peptides from centipede venoms

(2009) Kanfu Peng et al.   TOXICON

AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense

(2009) Yuping Lai et al.   TRENDS IN IMMUNOLOGY

Immune-related genes associated with intestinal tissue in the sea cucumber Holothuria glaberrima

(2008) Francisco Ramírez-Gómez et al.   IMMUNOGENETICS

Snake Cathelicidin from Bungarus fasciatus Is a Potent Peptide Antibiotics

(2008) Yipeng Wang et al.   PLoS One

A low molecular weight serine protease: Purification and characterization from Hippasa agelenoides (funnel web) spider venom gland extract

(2008) S. Devaraja et al.   TOXICON

Toxic activities of Brazilian centipede venoms

(2008) Marília B. Malta et al.   TOXICON

Comparative morphological study of the venom glands of the centipede Cryptops iheringi, Otostigmus pradoi and Scolopendra viridicornis

(2008) Marta M. Antoniazzi et al.   TOXICON

Potassium channels - multiplicity and challenges

(2006) Donald H Jenkinson   BRITISH JOURNAL OF PHARMACOLOGY