Pharmacological Alternatives for the Treatment of Neurodegenerative Disorders: Wasp and Bee Venoms and Their Components as New Neuroactive Tools

Parkinson's disease as a result of aging

(2015) Manuel Rodriguez et al.   AGING CELL

Neurobiology of l-DOPA induced dyskinesia and the novel therapeutic strategies

(2015) Sabeena Sharma et al.   BIOMEDICINE & PHARMACOTHERAPY

Classification, diagnosis, and differential diagnosis of multiple sclerosis

(2015) Ilana Katz Sand   CURRENT OPINION IN NEUROLOGY

Progressive multiple sclerosis

(2015) Daniel Ontaneda et al.   CURRENT OPINION IN NEUROLOGY

Recent insights into the mode of action of memantine and ketamine

(2015) Jon W Johnson et al.   CURRENT OPINION IN PHARMACOLOGY

Management of Parkinson׳s disease: Current and future pharmacotherapy

(2015) Ashish Kumar Kakkar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Human neural stem cell transplantation in ALS: initial results from a phase I trial

(2015) Letizia Mazzini et al.   Journal of Translational Medicine

Neuroprotective effects of bee venom acupuncture therapy against rotenone-induced oxidative stress and apoptosis

(2015) Wagdy K.B. Khalil et al.   NEUROCHEMISTRY INTERNATIONAL

Newer Agents in the Treatment of Multiple Sclerosis

(2015) Siddharama Pawate et al.   NEUROLOGIST

A review on Alzheimer's disease pathophysiology and its management: an update

(2015) Anil Kumar et al.   Pharmacological Reports

Results of Florida's Amyotrophic Lateral Sclerosis Surveillance Project, 2009-2011

(2015) C. Freer et al.   BMJ Open

Astrocyte-Derived TGF-β1 Accelerates Disease Progression in ALS Mice by Interfering with the Neuroprotective Functions of Microglia and T Cells

(2015) Fumito Endo et al.   Cell Reports

The Effects of Bee Venom Acupuncture on the Central Nervous System and Muscle in an Animal hSOD1G93A Mutant

(2015) MuDan Cai et al.   Toxins

Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan

(2015) Miguel Moreno et al.   Toxins

Transplantation of stem cell-derived astrocytes for the treatment of amyotrophic lateral sclerosis and spinal cord injury

(2015) Charles Nicaise   World Journal of Stem Cells

Action Processing and Mirror Neuron Function in Patients with Amyotrophic Lateral Sclerosis: An fMRI Study

(2015) Laura Jelsone-Swain et al.   PLoS One

Glutamate transporters in brain ischemia: to modulate or not?

(2014) Weronika Krzyżanowska et al.   ACTA PHARMACOLOGICA SINICA

The effects of the C-terminal amidation of mastoparans on their biological actions and interactions with membrane-mimetic systems

(2014) Alessandra V.R. da Silva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Neuroprotective effects of melittin on hydrogen peroxide-induced apoptotic cell death in neuroblastoma SH-SY5Y cells

(2014) Sang Mi Han et al.   BMC Complementary and Alternative Medicine

ILAE Official Report: A practical clinical definition of epilepsy

(2014) Robert S. Fisher et al.   EPILEPSIA

New Multiple Sclerosis Phenotypic Classification

(2014) Fred D. Lublin   EUROPEAN NEUROLOGY

Cognitive correlates in amyotrophic lateral sclerosis: a population-based study in Italy

(2014) A. Montuschi et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Is acupuncture efficacious therapy in Parkinson's disease?

(2014) Hee Jin Kim et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Inhibition of AMPA Receptors by Polyamine Toxins is Regulated by Agonist Efficacy and Stargazin

(2014) Mette H. Poulsen et al.   NEUROCHEMICAL RESEARCH

GLT-1 transporter: An effective pharmacological target for various neurological disorders

(2014) Neha Soni et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Spectrum of Cognitive Impairment in Korean ALS Patients without Known Genetic Mutations

(2014) Seong-il Oh et al.   PLoS One

Structure Analysis and Conformational Transitions of the Cell Penetrating Peptide Transportan 10 in the Membrane-Bound State

(2014) Susanne Fanghänel et al.   PLoS One

Pharmacological evaluation of bee venom and melittin

(2014) Camila G. Dantas et al.   Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

Concise Review: Stem Cell Therapies for Amyotrophic Lateral Sclerosis: Recent Advances and Prospects for the Future

(2014) J. Simon Lunn et al.   STEM CELLS

Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

(2014) Jeffrey L Cummings et al.   Alzheimers Research & Therapy

Bee venom acupuncture for rheumatoid arthritis: a systematic review of randomised clinical trials

(2014) Ju Ah Lee et al.   BMJ Open

Drug treatment of epilepsy in adults

(2014) D. Schmidt et al.   BMJ-British Medical Journal

Development of Potent Fluorescent Polyamine Toxins and Application in Labeling of Ionotropic Glutamate Receptors in Hippocampal Neurons

(2013) Niels G. Nørager et al.   ACS Chemical Biology

Bee venom effects on ubiquitin proteasome system in hSOD1G85R-expressing NSC34 motor neuron cells

(2013) Seon Hwy Kim et al.   BMC Complementary and Alternative Medicine

Potassium Channels: Structures, Diseases, and Modulators

(2013) Chuan Tian et al.   Chemical Biology & Drug Design

α-Synuclein Modification in an ALS Animal Model

(2013) Eun Jin Yang et al.   Evidence-based Complementary and Alternative Medicine

The therapeutic potential of small-conductance KCa2 channels in neurodegenerative and psychiatric diseases

(2013) Jenny Lam et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Demographic and clinical factors associated with changes in employment in multiple sclerosis

(2013) Phil Moore et al.   Multiple Sclerosis Journal

New avenues for anti-epileptic drug discovery and development

(2013) Wolfgang Löscher et al.   NATURE REVIEWS DRUG DISCOVERY

Biomarkers in Parkinson’s disease (recent update)

(2013) Sushil Sharma et al.   NEUROCHEMISTRY INTERNATIONAL

Global Epidemiology of Amyotrophic Lateral Sclerosis: A Systematic Review of the Published Literature

(2013) A. Chiò et al.   NEUROEPIDEMIOLOGY

Treatment of Parkinson’s Disease: What’s in the Non-dopaminergic Pipeline?

(2013) Albert Y. Hung et al.   Neurotherapeutics

Can 4-aminopyridine modulate dysfunctional gait networks in Parkinson's disease?

(2013) Corneliu C. Luca et al.   PARKINSONISM & RELATED DISORDERS

Bee Venom and Its Component Apamin as Neuroprotective Agents in a Parkinson Disease Mouse Model

(2013) Daniel Alvarez-Fischer et al.   PLoS One

Mastoparan-7 rescues botulinum toxin-A poisoned neurons in a mouse spinal cord cell culture model

(2013) Peng Zhang et al.   TOXICON

The life history of a botulinum toxin molecule

(2013) Lance Simpson   TOXICON

4-Aminopyridine for symptomatic treatment of multiple sclerosis: a systematic review

(2013) Henrik Boye Jensen et al.   Therapeutic Advances in Neurological Disorders

The genetics and neuropathology of amyotrophic lateral sclerosis

(2012) Ammar Al-Chalabi et al.   ACTA NEUROPATHOLOGICA

Pathogenesis and Disease-modifying Therapy in Alzheimer's Disease: The Flat Line of Progress

(2012) Rudy J. Castellani et al.   ARCHIVES OF MEDICAL RESEARCH

Neurological perspectives on voltage-gated sodium channels

(2012) N. Eijkelkamp et al.   BRAIN

Neuro-protective effects of bee venom by suppression of neuroinflammatory responses in a mouse model of Parkinson’s disease: Role of regulatory T cells

(2012) Eun Sook Chung et al.   BRAIN BEHAVIOR AND IMMUNITY

Ligand-Gated Ion Channels: New Insights into Neurological Disorders and Ligand Recognition

(2012) Damien Lemoine et al.   CHEMICAL REVIEWS

Crosstalk within GPCR Heteromers in Schizophrenia and Parkinsons Disease: Physical or Just Functional?

(2012) R. Guixa-Gonzalez et al.   CURRENT MEDICINAL CHEMISTRY

Finding a better drug for epilepsy: Preclinical screening strategies and experimental trial design

(2012) Michele Simonato et al.   EPILEPSIA

The significance of defining preclinical or prodromal Parkinson's disease

(2012) C. Warren Olanow et al.   MOVEMENT DISORDERS

Effectiveness of acupuncture and bee venom acupuncture in idiopathic Parkinson's disease

(2012) Seung-Yeon Cho et al.   PARKINSONISM & RELATED DISORDERS

Anticonvulsant and anxiolytic activity of the peptide fraction isolated from the venom of the social wasp Polybia paulista

(2012) MárciaRenata Mortari et al.   Pharmacognosy Magazine

Galanin Receptors and Ligands

(2012) Kristin E. B. Webling et al.   Frontiers in Endocrinology

Modern methods for delivery of drugs across the blood–brain barrier

(2011) Yan Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Multiple Sclerosis: New Insights in Pathogenesis and Novel Therapeutics

(2011) Daniel Ontaneda et al.   Annual Review of Medicine

Small-Conductance Ca2+-Activated K+ Channels: Form and Function

(2011) John P. Adelman et al.   Annual Review of Physiology

Lack of Evidence for the Efficacy of Memantine in Mild Alzheimer Disease

(2011) Lon S. Schneider   ARCHIVES OF NEUROLOGY

Bee venom protects SH-SY5Y human neuroblastoma cells from 1-methyl-4-phenylpyridinium-induced apoptotic cell death

(2011) Ah-Reum Doo et al.   BRAIN RESEARCH

Melittin Inhibits Atherosclerosis in LPS/High-Fat Treated Mice Through Atheroprotective Actions

(2011) Soo-Jung Kim et al.   Journal of Atherosclerosis and Thrombosis

Melittin restores proteasome function in an animal model of ALS

(2011) Eun Jin Yang et al.   Journal of Neuroinflammation

The role of G protein-coupled receptors in the pathology of Alzheimer's disease

(2011) Amantha Thathiah et al.   NATURE REVIEWS NEUROSCIENCE

Complementary and Alternative Medicine and Multiple Sclerosis

(2011) Allen C. Bowling   NEUROLOGIC CLINICS

Drug-Resistant Epilepsy

(2011) Patrick Kwan et al.   NEW ENGLAND JOURNAL OF MEDICINE

The future of Alzheimer's disease: The next 10 years

(2011) Harald Hampel et al.   PROGRESS IN NEUROBIOLOGY

Estimation of the burden of active and life-time epilepsy: A meta-analytic approach

(2010) Anthony K. Ngugi et al.   EPILEPSIA

Voltage-gated sodium channel isoform-specific effects of pompilidotoxins

(2010) Emanuele Schiavon et al.   FEBS Journal

Allosteric Block of KCa2 Channels by Apamin

(2010) Cédric Lamy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bee venom attenuates neuroinflammatory events and extends survival in amyotrophic lateral sclerosis models

(2010) Eun Jin Yang et al.   Journal of Neuroinflammation

Rate of familial amyotrophic lateral sclerosis: a systematic review and meta-analysis

(2010) S. Byrne et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Levodopa-induced dyskinesias in patients with Parkinson's disease: filling the bench-to-bedside gap

(2010) Paolo Calabresi et al.   LANCET NEUROLOGY

Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders

(2010) Massimo Mantegazza et al.   LANCET NEUROLOGY

Kinin Receptor Antagonists as Potential Neuroprotective Agents in Central Nervous System Injury

(2010) Emma Thornton et al.   MOLECULES

Dementia and cognitive impairment in amyotrophic lateral sclerosis: a review

(2010) Maria Teresa Giordana et al.   NEUROLOGICAL SCIENCES

β-pompilidotoxin modulates spontaneous activity and persistent sodium currents in spinal networks

(2010) V. Magloire et al.   NEUROSCIENCE

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases

(2009) Xiao-xia Dong et al.   ACTA PHARMACOLOGICA SINICA

Bradykinin-related peptides in the venom of the solitary wasp Cyphononyx fulvognathus

(2009) Gisele Picolo et al.   BIOCHEMICAL PHARMACOLOGY

Bradykinin Postconditioning Protects Pyramidal CA1 Neurons Against Delayed Neuronal Death in Rat Hippocampus

(2009) Viera Danielisová et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies

(2009) Patrick Kwan et al.   EPILEPSIA

The neurotoxicological effects of mastoparan Polybia-MPII at the murine neuromuscular junction: an ultrastructural and immunocytochemical study

(2009) Thalita Rocha et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Key factors in the discovery and development of new antiepileptic drugs

(2009) Meir Bialer et al.   NATURE REVIEWS DRUG DISCOVERY

Neuroprotective effects of bee venom pharmaceutical acupuncture in acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease

(2009) Ah-Reum Doo et al.   NEUROLOGICAL RESEARCH

The global burden and stigma of epilepsy

(2008) Hanneke M. de Boer et al.   EPILEPSY & BEHAVIOR

Venomics: unravelling the complexity of animal venoms with mass spectrometry

(2008) P. Escoubas et al.   JOURNAL OF MASS SPECTROMETRY

Bee Venom Acupuncture for Musculoskeletal Pain: A Review

(2008) Myeong Soo Lee et al.   JOURNAL OF PAIN

Structural diversity of G protein-coupled receptors and significance for drug discovery

(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY

Galanin Hyperinnervation Upregulates Choline Acetyltransferase Expression in Cholinergic Basal Forebrain Neurons in Alzheimer’s Disease

(2008) Scott E. Counts et al.   Neurodegenerative Diseases

Examining the evidence: complementary adjunctive therapies for multiple sclerosis

(2008) Mike Namaka et al.   NEUROLOGICAL RESEARCH