Glutamate transporters in brain ischemia: to modulate or not?

The chemistry and biological activities of N-acetylcysteine

(2013) Yuval Samuni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Age and meloxicam modify the response of the glutamate vesicular transporters (VGLUTs) after transient global cerebral ischemia in the rat brain

(2013) Irene L. Llorente et al.   BRAIN RESEARCH BULLETIN

Synaptic and Extrasynaptic NMDA Receptors Are Gated by Different Endogenous Coagonists

(2012) Thomas Papouin et al.   CELL

EAAC1 gene deletion alters zinc homeostasis and enhances cortical neuronal injury after transient cerebral ischemia in mice

(2012) Bong Geom Jang et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

N-acetylcysteine reverses existing cognitive impairment and increased oxidative stress in glutamate transporter type 3 deficient mice

(2012) L. Cao et al.   NEUROSCIENCE

Region-specific expression of vesicular glutamate and GABA transporters under various ischaemic conditions in mouse forebrain and retina

(2012) D. Michalski et al.   NEUROSCIENCE

Regulation of xCT expression and system $$ x_{\text{c}}^{ - } $$ function in neuronal cells

(2011) Jan Lewerenz et al.   AMINO ACIDS

Vesicular Neurotransmitter Transporter: Bioenergetics and Regulation of Glutamate Transport

(2011) Hiroshi Omote et al.   BIOCHEMISTRY

Changes in glutamate transporter expression in mouse forebrain areas following focal ischemia

(2011) Pirusha Ketheeswaranathan et al.   BRAIN RESEARCH

Maslinic acid, a natural triterpenoid compound from Olea europaea, protects cortical neurons against oxygen–glucose deprivation-induced injury

(2011) Yisong Qian et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The role of glutamate transporter-1a in the induction of brain ischemic tolerance in rats

(2011) Yi-Xian Liu et al.   GLIA

Regulation of the System x−C cystine/glutamate exchanger by intracellular glutathione levels in rat astrocyte primary cultures

(2011) Todd Michael Seib et al.   GLIA

Maslinic acid, a natural inhibitor of glycogen phosphorylase, reduces cerebral ischemic injury in hyperglycemic rats by GLT-1 up-regulation

(2011) Teng Guan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

From glutamate co-release to vesicular synergy: vesicular glutamate transporters

(2011) Salah El Mestikawy et al.   NATURE REVIEWS NEUROSCIENCE

Cleavage of the vesicular glutamate transporters under excitotoxic conditions

(2011) Andrea C. Lobo et al.   NEUROBIOLOGY OF DISEASE

The role of glutamate in neuronal ischemic injury: the role of spark in fire

(2011) Botros B. Kostandy   NEUROLOGICAL SCIENCES

Overview of glutamatergic neurotransmission in the nervous system

(2011) Mark J. Niciu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Targeted Over-Expression of Glutamate Transporter 1 (GLT-1) Reduces Ischemic Brain Injury in a Rat Model of Stroke

(2011) Brandon K. Harvey et al.   PLoS One

Hypoxic preconditioning involves system Xc− regulation in mouse neural stem cells

(2011) Brian Sims et al.   Stem Cell Research

VGLUT1 and VGLUT2 mRNA expression in the primate auditory pathway

(2010) Troy A. Hackett et al.   HEARING RESEARCH

Role of Excitatory Amino Acid Transporter-2 (EAAT2) and glutamate in neurodegeneration: Opportunities for developing novel therapeutics

(2010) Keetae Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Lactacidosis modulates glutathione metabolism and oxidative glutamate toxicity

(2010) Jan Lewerenz et al.   JOURNAL OF NEUROCHEMISTRY

EAAC1 Gene Deletion Alters Zinc Homeostasis and Exacerbates Neuronal Injury after Transient Cerebral Ischemia

(2010) S. J. Won et al.   JOURNAL OF NEUROSCIENCE

Primary Cultures From Cerebral Cortex and Hippocampus Enriched in Glutamatergic and GABAergic Neurons

(2010) Ulrika Björklund et al.   NEUROCHEMICAL RESEARCH

Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons

(2010) Jian Zou et al.   NEUROCHEMISTRY INTERNATIONAL

Metabolic Control of Vesicular Glutamate Transport and Release

(2010) Narinobu Juge et al.   NEURON

Volatile Anesthetics Attenuate Oxidative Stress-Reduced Activity of Glutamate Transporter Type 3

(2009) Soon-Ae Lee et al.   ANESTHESIA AND ANALGESIA

Mitochondria, calcium and cell death: A deadly triad in neurodegeneration

(2009) Fulvio Celsi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxonein vitro

(2009) Jan Lewerenz et al.   JOURNAL OF NEUROCHEMISTRY

Amitriptyline inhibits the activity of the rat glutamate transporter EAAT3 expressed in Xenopus oocytes

(2009) Hee-Jung Baik et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors

(2009) Rebecca P. Seal et al.   NATURE

Increased expression of glutamate transporters in subcortical white matter after transient focal cerebral ischemia

(2009) Amaia M. Arranz et al.   NEUROBIOLOGY OF DISEASE

Metabotropic glutamate receptors in the tripartite synapse as a target for new psychotropic drugs

(2009) Joanna M. Wierońska et al.   NEUROCHEMISTRY INTERNATIONAL

Receptor Actions of Synaptically Released Glutamate: The Role of Transporters on the Scale from Nanometers to Microns

(2008) Kaiyu Zheng et al.   BIOPHYSICAL JOURNAL

Inability of volatile anesthetics to inhibit oxygen–glucose deprivation-induced glutamate release via glutamate transporters and anion channels in rat corticostriatal slices

(2008) Hae-Hyuk Jung et al.   BRAIN RESEARCH

Excitatory amino acid transporter expression by astrocytes is neuroprotective against microglial excitotoxicity

(2008) Jianfeng Liang et al.   BRAIN RESEARCH

Glutamate forward and reverse transport: From molecular mechanism to transporter-mediated release after ischemia

(2008) Christof Grewer et al.   IUBMB LIFE

Basal Levels of eIF2α Phosphorylation Determine Cellular Antioxidant Status by Regulating ATF4 and xCT Expression

(2008) Jan Lewerenz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of Ceftriaxone Induction of Excitatory Amino Acid Transporter-2 Expression and Glutamate Uptake in Primary Human Astrocytes

(2008) Seok-Geun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-affinity Na+/K+-dependent glutamate transporter EAAT4 is expressed throughout the rat fore- and midbrain

(2008) Ann Massie et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

(2008) Sofia Papadia et al.   NATURE NEUROSCIENCE

Presynaptic glutamate receptors: physiological functions and mechanisms of action

(2008) Paulo S. Pinheiro et al.   NATURE REVIEWS NEUROSCIENCE

Sensorineural Deafness and Seizures in Mice Lacking Vesicular Glutamate Transporter 3

(2008) Rebecca P. Seal et al.   NEURON

Amitriptyline induces nuclear transcription factor-κB–dependent glutamate transporter upregulation in chronic morphine-infused rats

(2008) Y.-H. Tai et al.   NEUROSCIENCE

Mood disorders: Regulation by metabotropic glutamate receptors

(2007) Andrzej Pilc et al.   BIOCHEMICAL PHARMACOLOGY

Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1

(2007) Elena Fumagalli et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mechanisms of glutamate release from astrocytes

(2007) Erik B. Malarkey et al.   NEUROCHEMISTRY INTERNATIONAL