A Two-Component DNA-Prime/Protein-Boost Vaccination Strategy for Eliciting Long-Term, Protective T Cell Immunity against Trypanosoma cruzi

Infection with Trypanosoma cruzi Restricts the Repertoire of Parasite-Specific CD8+ T Cells Leading to Immunodominance

(2014) F. Tzelepis et al.   JOURNAL OF IMMUNOLOGY

CD8+T Cell-Mediated Immunity duringTrypanosoma cruziInfection: A Path for Vaccine Development?

(2014) Fernando dos Santos Virgilio et al.   MEDIATORS OF INFLAMMATION

Chagas Disease Cardiomyopathy: Immunopathology and Genetics

(2014) Edecio Cunha-Neto et al.   MEDIATORS OF INFLAMMATION

Chronic Parasitic Infection Maintains High Frequencies of Short-Lived Ly6C+CD4+ Effector T Cells That Are Required for Protection against Re-infection

(2014) Nathan C. Peters et al.   PLoS Pathogens

TcVac3 Induced Control of Trypanosoma cruzi Infection and Chronic Myocarditis in Mice

(2013) Shivali Gupta et al.   PLoS One

NLRP3 Controls Trypanosoma cruzi Infection through a Caspase-1-Dependent IL-1R-Independent NO Production

(2013) Virginia M. Gonçalves et al.   PLoS Neglected Tropical Diseases

High Interleukin 17 Expression Is Correlated With Better Cardiac Function in Human Chagas Disease

(2012) Luisa M. D. Magalhães et al.   JOURNAL OF INFECTIOUS DISEASES

Diagnosis and management of Chagas disease and cardiomyopathy

(2012) Antonio L. Ribeiro et al.   Nature Reviews Cardiology

Current understanding of immunity to Trypanosoma cruzi infection and pathogenesis of Chagas disease

(2012) Fabiana S. Machado et al.   Seminars in Immunopathology

Pathogen-Induced Proapoptotic Phenotype and High CD95 (Fas) Expression Accompany a Suboptimal CD8+ T-Cell Response: Reversal by Adenoviral Vaccine

(2012) José Ronnie Vasconcelos et al.   PLoS Pathogens

Trypanosoma cruzi and Chagas' Disease in the United States

(2011) C. Bern et al.   CLINICAL MICROBIOLOGY REVIEWS

Heterologous Plasmid DNA Prime-Recombinant Human Adenovirus 5 Boost Vaccination Generates a Stable Pool of Protective Long-Lived CD8+T Effector Memory Cells Specific for a Human Parasite, Trypanosoma cruzi

(2011) Paula Ordonhez Rigato et al.   INFECTION AND IMMUNITY

Co-Administration of a Plasmid DNA Encoding IL-15 Improves Long-Term Protection of a Genetic Vaccine against Trypanosoma cruzi

(2011) Christopher S. Eickhoff et al.   PLoS Neglected Tropical Diseases

Testing the Efficacy of a Multi-Component DNA-Prime/DNA-Boost Vaccine against Trypanosoma cruzi Infection in Dogs

(2011) José E. Aparicio-Burgos et al.   PLoS Neglected Tropical Diseases

Chagas Disease Has Now Gone Global

(2011) Herbert B. Tanowitz et al.   PLoS Neglected Tropical Diseases

Phenyl-α-tert-butyl-nitrone and Benzonidazole Treatment Controlled the Mitochondrial Oxidative Stress and Evolution of Cardiomyopathy in Chronic Chagasic Rats

(2010) Jian-Jun Wen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effect of a combination DNA vaccine for the prevention and therapy of Trypanosoma cruzi infection in mice: Role of CD4+ and CD8+ T cells

(2010) Alberto Yairh Limon-Flores et al.   VACCINE

The Potential Economic Value of a Trypanosoma cruzi (Chagas Disease) Vaccine in Latin America

(2010) Bruce Y. Lee et al.   PLoS Neglected Tropical Diseases

Prophylactic Efficacy of TcVac2 against Trypanosoma cruzi in Mice

(2010) Shivali Gupta et al.   PLoS Neglected Tropical Diseases

Immunogenicity of a Standard Trivalent Influenza Vaccine in Patients on Long-term Hemodialysis: An Open-Label Trial

(2009) Johan Scharpé et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Quick to remember, slow to forget: rapid recall responses of memory CD8+ T cells

(2009) Joanna R DiSpirito et al.   CELL RESEARCH

An Estimate of the Burden of Chagas Disease in the United States

(2009) Caryn Bern et al.   CLINICAL INFECTIOUS DISEASES

CD8+ T cells in Trypanosoma cruzi infection

(2009) Angel M Padilla et al.   CURRENT OPINION IN IMMUNOLOGY

Perforin and Gamma Interferon Expression Are Required for CD4+ and CD8+ T-Cell-Dependent Protective Immunity against a Human Parasite, Trypanosoma cruzi, Elicited by Heterologous Plasmid DNA Prime-Recombinant Adenovirus 5 Boost Vaccination

(2009) B. C. G. de Alencar et al.   INFECTION AND IMMUNITY

Cutting Edge: Nucleotide-Binding Oligomerization Domain 1-Dependent Responses Account for Murine Resistance against Trypanosoma cruzi Infection

(2009) G. K. Silva et al.   JOURNAL OF IMMUNOLOGY

Perspectives on Trypanosoma cruzi–Induced Heart Disease (Chagas Disease)

(2009) Herbert B. Tanowitz et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Protective effect of a RSV subunit vaccine candidate G1F/M2 was enhanced by a HSP70-Like protein in mice

(2008) Ruihong Zeng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Previously Unrecognized Vaccine Candidates Control Trypanosoma cruzi Infection and Immunopathology in Mice

(2008) V. Bhatia et al.   Clinical and Vaccine Immunology

Current concepts in immunoregulation and pathology of human Chagas disease

(2008) Walderez O Dutra et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Broad Immunogenicity of a Multigene, Multiclade HIV‐1 DNA Vaccine Boosted with Heterologous HIV‐1 Recombinant Modified Vaccinia Virus Ankara

(2008) Eric Sandström et al.   JOURNAL OF INFECTIOUS DISEASES

Memory CD8 T-cell compartment grows in size with immunological experience

(2008) Vaiva Vezys et al.   NATURE

Drug-induced cure drives conversion to a stable and protective CD8+ T central memory response in chronic Chagas disease

(2008) Juan M Bustamante et al.   NATURE MEDICINE