The Newest “Omics”—Metagenomics and Metabolomics—Enter the Battle against the Neglected Tropical Diseases

Review article: evidence for the role of gut microbiota in irritable bowel syndrome and its potential influence on therapeutic targets

(2014) H. L. DuPont   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Kingdom-Agnostic Metagenomics and the Importance of Complete Characterization of Enteric Microbial Communities

(2014) Jason M. Norman et al.   GASTROENTEROLOGY

Compositional and Functional Features of the Gastrointestinal Microbiome and Their Effects on Human Health

(2014) Emily B. Hollister et al.   GASTROENTEROLOGY

Meta'omic Analytic Techniques for Studying the Intestinal Microbiome

(2014) Xochitl C. Morgan et al.   GASTROENTEROLOGY

Impact of Experimental Hookworm Infection on the Human Gut Microbiota

(2014) Cinzia Cantacessi et al.   JOURNAL OF INFECTIOUS DISEASES

The Undernourished Neonatal Mouse Metabolome Reveals Evidence of Liver and Biliary Dysfunction, Inflammation, and Oxidative Stress

(2014) Geoffrey A. Preidis et al.   JOURNAL OF NUTRITION

Dynamics and associations of microbial community types across the human body

(2014) Tao Ding et al.   NATURE

In Silico Analysis of Antibiotic Resistance Genes in the Gut Microflora of Individuals from Diverse Geographies and Age-Groups

(2014) Tarini Shankar Ghosh et al.   PLoS One

Targeting NAD+ Metabolism in the Human Malaria Parasite Plasmodium falciparum

(2014) Jessica K. O'Hara et al.   PLoS One

Metabolic QTL Analysis Links Chloroquine Resistance in Plasmodium falciparum to Impaired Hemoglobin Catabolism

(2014) Ian A. Lewis et al.   PLoS Genetics

Benznidazole Biotransformation and Multiple Targets in Trypanosoma cruzi Revealed by Metabolomics

(2014) Andrea Trochine et al.   PLoS Neglected Tropical Diseases

Scabies Mites Alter the Skin Microbiome and Promote Growth of Opportunistic Pathogens in a Porcine Model

(2014) Pearl M. Swe et al.   PLoS Neglected Tropical Diseases

Induction of a Stringent Metabolic Response in Intracellular Stages of Leishmania mexicana Leads to Increased Dependence on Mitochondrial Metabolism

(2014) Eleanor C. Saunders et al.   PLoS Pathogens

BCKDH: The Missing Link in Apicomplexan Mitochondrial Metabolism Is Required for Full Virulence of Toxoplasma gondii and Plasmodium berghei

(2014) Rebecca D. Oppenheim et al.   PLoS Pathogens

Neglected Infections of Poverty in the United States and Their Effects on the Brain

(2014) Peter J. Hotez   JAMA Psychiatry

Mitochondrial metabolism of sexual and asexual blood stages of the malaria parasite Plasmodium falciparum

(2013) James I MacRae et al.   BMC BIOLOGY

Infection with the carcinogenic liver fluke Opisthorchis viverrini modifies intestinal and biliary microbiome

(2013) Jordan L. Plieskatt et al.   FASEB JOURNAL

A genomic portrait of the emergence, evolution, and global spread of a methicillin-resistant Staphylococcus aureus pandemic

(2013) M. T. G. Holden et al.   GENOME RESEARCH

A novel approach, based on BLSOMs (Batch Learning Self-Organizing Maps), to the microbiome analysis of ticks

(2013) Ryo Nakao et al.   ISME Journal

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Antibiotics as Part of the Management of Severe Acute Malnutrition

(2013) Indi Trehan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ribosomal Database Project: data and tools for high throughput rRNA analysis

(2013) James R. Cole et al.   NUCLEIC ACIDS RESEARCH

Metabolic Profiling for Detection of Staphylococcus aureus Infection and Antibiotic Resistance

(2013) Henrik Antti et al.   PLoS One

Patent Human Infections with the Whipworm, Trichuris trichiura, Are Not Associated with Alterations in the Faecal Microbiota

(2013) Philip Cooper et al.   PLoS One

Onchocerca volvulus-neurotransmitter tyramine is a biomarker for river blindness

(2013) Daniel Globisch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor

(2013) M. I. Smith et al.   SCIENCE

The Long-Term Stability of the Human Gut Microbiota

(2013) J. J. Faith et al.   SCIENCE

Metabonomics Reveals Drastic Changes in Anti-Inflammatory/Pro-Resolving Polyunsaturated Fatty Acids-Derived Lipid Mediators in Leprosy Disease

(2013) Julio J. Amaral et al.   PLoS Neglected Tropical Diseases

Serum Metabolome and Lipidome Changes in Adult Patients with Primary Dengue Infection

(2013) Liang Cui et al.   PLoS Neglected Tropical Diseases

Trypanosome Infection Establishment in the Tsetse Fly Gut Is Influenced by Microbiome-Regulated Host Immune Barriers

(2013) Brian L. Weiss et al.   PLoS Pathogens

Chronic Gastrointestinal Consequences of Acute Infectious Diarrhea: Evolving Concepts in Epidemiology and Pathogenesis

(2012) Elena F Verdu et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Mitochondrial Metabolism of Glucose and Glutamine Is Required for Intracellular Growth of Toxoplasma gondii

(2012) James I. MacRae et al.   Cell Host & Microbe

Alterations in the Porcine Colon Microbiota Induced by the Gastrointestinal Nematode Trichuris suis

(2012) Robert W. Li et al.   INFECTION AND IMMUNITY

Metagenomic and Metabolomic Characterization of Rabies Encephalitis: New Insights into the Treatment of an Ancient Disease

(2012) Stacey N. Reinke et al.   JOURNAL OF INFECTIOUS DISEASES

MRSA epidemic linked to a quickly spreading colonization and virulence determinant

(2012) Min Li et al.   NATURE MEDICINE

The impoverished gut—a triple burden of diarrhoea, stunting and chronic disease

(2012) Richard L. Guerrant et al.   Nature Reviews Gastroenterology & Hepatology

The keystone-pathogen hypothesis

(2012) George Hajishengallis et al.   NATURE REVIEWS MICROBIOLOGY

Trypanosoma cruzi Immune Response Modulation Decreases Microbiota in Rhodnius prolixus Gut and Is Crucial for Parasite Survival and Development

(2012) Daniele P. Castro et al.   PLoS One

The human gut microbiome: current knowledge, challenges, and future directions

(2012) Maneesh Dave et al.   Translational Research

Hyperlipidaemia in trypanosomiasis of naturally infected horses: possible cachexia–anorexia syndrome?

(2012) Muthusamy Ranjithkumar et al.   TROPICAL ANIMAL HEALTH AND PRODUCTION

Treatment for Schistosoma japonicum, Reduction of Intestinal Parasite Load, and Cognitive Test Score Improvements in School-Aged Children

(2012) Amara E. Ezeamama et al.   PLoS Neglected Tropical Diseases

Untargeted Metabolomics Reveals a Lack Of Synergy between Nifurtimox and Eflornithine against Trypanosoma brucei

(2012) Isabel M. Vincent et al.   PLoS Neglected Tropical Diseases

Dramatic Increase in Glycerol Biosynthesis upon Oxidative Stress in the Anaerobic Protozoan Parasite Entamoeba histolytica

(2012) Afzal Husain et al.   PLoS Neglected Tropical Diseases

Virus Identification in Unknown Tropical Febrile Illness Cases Using Deep Sequencing

(2012) Nathan L. Yozwiak et al.   PLoS Neglected Tropical Diseases

Metabonomic investigation of human Schistosoma mansoni infection

(2011) Crina I. A. Balog et al.   Molecular BioSystems

The Gut as Reservoir of Antibiotic Resistance: Microbial Diversity of Tetracycline Resistance in Mother and Infant

(2011) Lisbeth E. de Vries et al.   PLoS One

Serum Metabolomics Reveals Higher Levels of Polyunsaturated Fatty Acids in Lepromatous Leprosy: Potential Markers for Susceptibility and Pathogenesis

(2011) Reem Al-Mubarak et al.   PLoS Neglected Tropical Diseases

Metagenomic Analysis of Taxa Associated with Lutzomyia longipalpis, Vector of Visceral Leishmaniasis, Using an Unbiased High-Throughput Approach

(2011) Christina B. McCarthy et al.   PLoS Neglected Tropical Diseases

Probiotics, Enteric and Diarrheal Diseases, and Global Health

(2010) Geoffrey A. Preidis et al.   GASTROENTEROLOGY

Urinary metabonomics study in a rat model in response to protein-energy malnutrition by using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry

(2010) Zeming Wu et al.   Molecular BioSystems

Systems parasitology: effects of Fasciola hepatica on the neurochemical profile in the rat brain

(2010) Jasmina Saric et al.   Molecular Systems Biology

Evolution of MRSA During Hospital Transmission and Intercontinental Spread

(2010) S. R. Harris et al.   SCIENCE

Arbovirus Detection in Insect Vectors by Rapid, High-Throughput Pyrosequencing

(2010) Kimberly A. Bishop-Lilly et al.   PLoS Neglected Tropical Diseases

Metabolomics-Based Discovery of Diagnostic Biomarkers for Onchocerciasis

(2010) Judith R. Denery et al.   PLoS Neglected Tropical Diseases

Metabolic Changes Reveal the Development of Schistosomiasis in Mice

(2010) Junfang Wu et al.   PLoS Neglected Tropical Diseases

Metabolomics to Unveil and Understand Phenotypic Diversity between Pathogen Populations

(2010) Ruben t'Kindt et al.   PLoS Neglected Tropical Diseases

A Timescale for Evolution, Population Expansion, and Spatial Spread of an Emerging Clone of Methicillin-Resistant Staphylococcus aureus

(2010) Ulrich Nübel et al.   PLoS Pathogens

Like Will to Like: Abundances of Closely Related Species Can Predict Susceptibility to Intestinal Colonization by Pathogenic and Commensal Bacteria

(2010) Bärbel Stecher et al.   PLoS Pathogens

LeishCyc: a biochemical pathways database for Leishmania major

(2009) Maria A Doyle et al.   BMC Systems Biology

Targeting the Human Microbiome With Antibiotics, Probiotics, and Prebiotics: Gastroenterology Enters the Metagenomics Era

(2009) Geoffrey A. Preidis et al.   GASTROENTEROLOGY

Recent human-to-poultry host jump, adaptation, and pandemic spread of Staphylococcus aureus

(2009) B. V. Lowder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Characterization of the Antibiotic Resistance Reservoir in the Human Microflora

(2009) M. O. A. Sommer et al.   SCIENCE

Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes

(2008) Sandrine P Claus et al.   Molecular Systems Biology

Probiotic modulation of symbiotic gut microbial–host metabolic interactions in a humanized microbiome mouse model

(2008) Francois-Pierre J Martin et al.   Molecular Systems Biology

Malnutrition as an enteric infectious disease with long-term effects on child development

(2008) Richard L Guerrant et al.   NUTRITION REVIEWS

The role of microbiota in infectious disease

(2008) Bärbel Stecher et al.   TRENDS IN MICROBIOLOGY

Metabolic Profiling of an Echinostoma caproni Infection in the Mouse for Biomarker Discovery

(2008) Jasmina Saric et al.   PLoS Neglected Tropical Diseases