Targeting NAD+ Metabolism in the Human Malaria Parasite Plasmodium falciparum

Malaria biology and disease pathogenesis: insights for new treatments

(2013) Louis H Miller et al.   NATURE MEDICINE

Sir2a regulates rDNA transcription and multiplication rate in the human malaria parasite Plasmodium falciparum

(2013) Liliana Mancio-Silva et al.   Nature Communications

Overview of Pyridine Nucleotides Review Series

(2012) Michinari Nakamura et al.   CIRCULATION RESEARCH

Leishmania infantum nicotinamidase is required for late-stage development in its natural sand fly vector, Phlebotomus perniciosus

(2012) Elodie Gazanion et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Thioredoxin and glutathione systems in Plasmodium falciparum

(2012) Esther Jortzik et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

The Phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii Reveal Unusual Adaptations Within and Beyond the Parasites' Boundaries

(2011) Moritz Treeck et al.   Cell Host & Microbe

NMN/NaMN Adenylyltransferase (NMNAT) and NAD Kinase (NADK) Inhibitors: Chemistry and Potential Therapeutic Applications

(2011) R. Petrelli et al.   CURRENT MEDICINAL CHEMISTRY

NMNAT Expression and its Relation to NAD Metabolism

(2011) H. N. Jayaram et al.   CURRENT MEDICINAL CHEMISTRY

The Leishmania nicotinamidase is essential for NAD+ production and parasite proliferation

(2011) E. Gazanion et al.   MOLECULAR MICROBIOLOGY

Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum

(2011) Ellen Yeh et al.   PLOS BIOLOGY

Complexes of Bacterial Nicotinate Mononucleotide Adenylyltransferase with Inhibitors: Implication for Structure-Based Drug Design and Improvement

(2010) Nian Huang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Protein Export Marks the Early Phase of Gametocytogenesis of the Human Malaria ParasitePlasmodium falciparum

(2010) Francesco Silvestrini et al.   MOLECULAR & CELLULAR PROTEOMICS

Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network

(2010) Germán Plata et al.   Molecular Systems Biology

Host-Parasite Interactions Revealed by Plasmodium falciparum Metabolomics

(2009) Kellen L. Olszewski et al.   Cell Host & Microbe

Targeting NAD Biosynthesis in Bacterial Pathogens: Structure-Based Development of Inhibitors of Nicotinate Mononucleotide Adenylyltransferase NadD

(2009) Leonardo Sorci et al.   CHEMISTRY & BIOLOGY

The NMN/NaMN adenylyltransferase (NMNAT) protein family

(2009) Corinna Lau   Frontiers in Bioscience-Landmark

High-Affinity Transporters for NAD+ Precursors in Candida glabrata Are Regulated by Hst1 and Induced in Response to Niacin Limitation

(2009) B. Ma et al.   MOLECULAR AND CELLULAR BIOLOGY

Sir2 Paralogues Cooperate to Regulate Virulence Genes and Antigenic Variation in Plasmodium falciparum

(2009) Christopher J Tonkin et al.   PLOS BIOLOGY

Structure of nicotinic acid mononucleotide adenylyltransferase fromBacillus anthracis

(2008) Shanyun Lu et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition

(2008) Katrina L Bogan et al.   Annual Review of Nutrition

Saccharomyces cerevisiae YOR071CEncodes the High Affinity Nicotinamide Riboside Transporter Nrt1

(2008) Peter A. Belenky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolite profiling of the intraerythrocytic malaria parasitePlasmodium falciparumby1H NMR spectroscopy

(2008) Rongwei Teng et al.   NMR IN BIOMEDICINE