Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains

Genetic Architecture of Insulin Resistance in the Mouse

(2015) Brian W. Parks et al.   Cell Metabolism

Genetics of common forms of heart failure

(2015) Christoph D. Rau et al.   CURRENT OPINION IN CARDIOLOGY

An integrated genomic-transcriptomic approach supports a role for the proto-oncogene BCL3 in atherosclerosis

(2015) Giovanna Marchetti et al.   THROMBOSIS AND HAEMOSTASIS

Loss-of-Function Mutations in WDR73 Are Responsible for Microcephaly and Steroid-Resistant Nephrotic Syndrome: Galloway-Mowat Syndrome

(2014) Estelle Colin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Measurement of trimethylamine-N-oxide by stable isotope dilution liquid chromatography tandem mass spectrometry

(2014) Zeneng Wang et al.   ANALYTICAL BIOCHEMISTRY

Comparative Genome-Wide Association Studies in Mice and Humans for Trimethylamine N -Oxide, a Proatherogenic Metabolite of Choline and l -Carnitine

(2014) Jaana Hartiala et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Quantitative Trait Loci Affecting Atherosclerosis at the Aortic Root Identified in an Intercross between DBA2J and 129S6 Apolipoprotein E-Null Mice

(2014) Yukako Kayashima et al.   PLoS One

Searching for missing heritability: Designing rare variant association studies

(2014) O. Zuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

L-selectin deficiency decreases aortic B1a and Breg subsets and promotes atherosclerosis

(2014) Breanne Gjurich et al.   THROMBOSIS AND HAEMOSTASIS

Functions of Arginase Isoforms in Macrophage Inflammatory Responses: Impact on Cardiovascular Diseases and Metabolic Disorders

(2014) Zhihong Yang et al.   Frontiers in Immunology

Gene Expression Analyses of Mouse Aortic Endothelium in Response to Atherogenic Stimuli

(2013) Ayca Erbilgin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation

(2013) Brian J. Bennett et al.   Cell Metabolism

Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

(2013) Brian W. Parks et al.   Cell Metabolism

Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways

(2013) Dexi Zhou et al.   CELLULAR SIGNALLING

Myeloid cells in atherosclerosis

(2013) Ekaterina K. Koltsova et al.   CURRENT OPINION IN LIPIDOLOGY

Genome-wide association study of chronic periodontitis in a general German population

(2013) Alexander Teumer et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Genome-wide association mapping of blood cell traits in mice

(2013) Richard C. Davis et al.   MAMMALIAN GENOME

Finding the sources of missing heritability in a yeast cross

(2013) Joshua S. Bloom et al.   NATURE

Dysfunctional nitric oxide signalling increases risk of myocardial infarction

(2013) Jeanette Erdmann et al.   NATURE

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

The heritability of human disease: estimation, uses and abuses

(2013) Albert Tenesa et al.   NATURE REVIEWS GENETICS

Systems genetics approaches to understand complex traits

(2013) Mete Civelek et al.   NATURE REVIEWS GENETICS

Transcriptome Analysis of Genes Regulated by Cholesterol Loading in Two Strains of Mouse Macrophages Associates Lysosome Pathway and ER Stress Response with Atherosclerosis Susceptibility

(2013) Stela Z. Berisha et al.   PLoS One

Large Scale Comparison of Gene Expression Levels by Microarrays and RNAseq Using TCGA Data

(2013) Yan Guo et al.   PLoS One

Unraveling Inflammatory Responses using Systems Genetics and Gene-Environment Interactions in Macrophages

(2012) Luz D. Orozco et al.   CELL

Genetics of Human Cardiovascular Disease

(2012) Sekar Kathiresan et al.   CELL

Effect of 9p21.3 Coronary Artery Disease Locus Neighboring Genes on Atherosclerosis in Mice

(2012) Juyong Brian Kim et al.   CIRCULATION

Heart Disease and Stroke Statistics—2013 Update

(2012) Alan S. Go et al.   CIRCULATION

Genetic Basis of Atherosclerosis: Insights From Mice and Humans

(2012) Ioannis M. Stylianou et al.   CIRCULATION RESEARCH

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

(2012) Benjamin F Voight et al.   LANCET

Myocardial infarction accelerates atherosclerosis

(2012) Partha Dutta et al.   NATURE

Large-scale association analysis identifies new risk loci for coronary artery disease

(2012) Panos Deloukas et al.   NATURE GENETICS

Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease

(2012) Xiangfeng Lu et al.   NATURE GENETICS

A travel guide to Cytoscape plugins

(2012) Rintaro Saito et al.   NATURE METHODS

Genome-wide association studies in mice

(2012) Jonathan Flint et al.   NATURE REVIEWS GENETICS

Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion

(2012) D. Samanta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mystery of missing heritability: Genetic interactions create phantom heritability

(2012) O. Zuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetics of atherosclerosis

(2012) Aldons J. Lusis   TRENDS IN GENETICS

Monocyte and Macrophage Dynamics During Atherogenesis

(2011) Klaus Ley et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Arginine bioavailability ratios are associated with cardiovascular mortality in patients referred to coronary angiography

(2011) Harald Sourij et al.   ATHEROSCLEROSIS

Gene networks associated with conditional fear in mice identified using a systems genetics approach

(2011) Christopher C Park et al.   BMC Systems Biology

Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour

(2011) J. F. Peden et al.   HUMAN MOLECULAR GENETICS

FaST linear mixed models for genome-wide association studies

(2011) Christoph Lippert et al.   NATURE METHODS

Mouse Genome-Wide Association and Systems Genetics Identify Asxl2 As a Regulator of Bone Mineral Density and Osteoclastogenesis

(2011) Charles R. Farber et al.   PLoS Genetics

Comparative Analysis of Proteome and Transcriptome Variation in Mouse

(2011) Anatole Ghazalpour et al.   PLoS Genetics

NF-E2–Related Factor 2 Promotes Atherosclerosis by Effects on Plasma Lipoproteins and Cholesterol Transport That Overshadow Antioxidant Protection

(2010) Berenice Barajas et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

A high-resolution association mapping panel for the dissection of complex traits in mice

(2010) B. J. Bennett et al.   GENOME RESEARCH

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

(2010) Kiran Musunuru et al.   NATURE

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Genetic Regulation of Atherosclerotic Plaque Size and Morphology in the Innominate Artery of Hyperlipidemic Mice

(2009) Brian J. Bennett et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Targeted Metabolomic Evaluation of Arginine Methylation and Cardiovascular Risks

(2009) Zeneng Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Four additional mouse crosses improve the lipid QTL landscape and identifyLipgas a QTL gene

(2009) Zhiguang Su et al.   JOURNAL OF LIPID RESEARCH

Diminished Global Arginine Bioavailability and Increased Arginine Catabolism as Metabolic Profile of Increased Cardiovascular Risk

(2009) W.H. Wilson Tang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A customized and versatile high-density genotyping array for the mouse

(2009) Hyuna Yang et al.   NATURE METHODS

A Systems Genetics Approach Implicates USF1, FADS3, and Other Causal Candidate Genes for Familial Combined Hyperlipidemia

(2009) Christopher L. Plaisier et al.   PLoS Genetics

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Glucose Metabolism In Vivo in Four Commonly Used Inbred Mouse Strains

(2008) E. D. Berglund et al.   DIABETES

Elucidating the Role of Gonadal Hormones in Sexually Dimorphic Gene Coexpression Networks

(2008) Atila van Nas et al.   ENDOCRINOLOGY

High-Resolution Mapping of Gene Expression Using Association in an Outbred Mouse Stock

(2008) Anatole Ghazalpour et al.   PLoS Genetics

Interleukin-8 as an independent predictor of long-term clinical outcome in patients with coronary artery disease

(2007) Teruo Inoue et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY