Article
Nanoscience & Nanotechnology
Sumin Kim, Young-Geun Park, Ju-Young Kim, Enji Kim, Dong Ha Lee, Jae-Hyun Lee, Jinwoo Cheon, Jang-Ung Park
Summary: A liquid form of ECG electrodes is introduced in this paper, which can be magnetically reconfigured on human skin by providing conformal interfacing. These electrodes consist of biocompatible liquid-metal droplets with homogeneously dispersed magnetic particles, and their conformal contact with skin can significantly reduce impedance and improve the signal-to-noise ratio of ECG peaks. The electrodes are also capable of complex motions such as linear movements, splitting, and merging under external magnetic fields. Furthermore, magnetic manipulation of the electrode position on human skin enables precise monitoring of ECG signals with the change in ECG vectors. The integration of liquid-state electrodes with electronic circuitry allows for wireless and continuous ECG monitoring by magnetically moving the entire system on human skin.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Moohyun Kim, Jae Chul Hwang, Sungjin Min, Young-Geun Park, Suran Kim, Enji Kim, Hunkyu Seo, Won Gi Chung, Jakyoung Lee, Seung-Woo Cho, Jang-Ung Park
Summary: In this study, an unconventional method for multimodal characterization of three-dimensional cardiac organoids is presented. The method utilizes an active-matrix array of pressure-sensitive transistors to visualize the local pressure distributions of human-induced pluripotent stem-cell-derived cardiac organoids, and integrates it with three-dimensional electrodes formed by high-resolution printing of liquid metal for simultaneous electrophysiological recording and stimulation. This method enables electrical therapeutics of cardiac organoids without any interference between pressure signals and electrical pulses from pacing electrodes.
Review
Chemistry, Multidisciplinary
Yo Han Cho, Young-Geun Park, Sumin Kim, Jang-Ung Park
Summary: In recent years, significant efforts have been made to develop 3D electrodes for bioelectronic devices, allowing for better interfaces with nonplanar and soft biological systems. These 3D bioelectrodes have shown great potential for applications in 3D organoids and deep tissues, with research focusing on electrical stimulation and neural signal recording.
ADVANCED MATERIALS
(2021)
Article
Engineering, Biomedical
Can Aslan, Jeremy L. Gilbert
Summary: This study investigated the corrosion behavior and metal ion release of the Essure (R) permanent contraceptive implant during storage in different solutions. The results showed that the tin-silver solder corroded continuously in phosphate buffered saline and hydrogen peroxide solution, while the corrosion was minimal in formalin storage. This study provides important insights into the long-term performance and safety of the Essure (R) implant.
ACTA BIOMATERIALIA
(2022)
Article
Engineering, Biomedical
Xin Zhou, Ashna Rajeev, Arunprabaharan Subramanian, Yang Li, Nicolo Rossetti, Giovanniantonio Natale, Gregory A. A. Lodygensky, Fabio Cicoira
Summary: In this study, self-healing, stretchable, highly adhesive and conductive hydrogels were developed for bioelectronics and wearable electronics applications. These hydrogels exhibited high adhesion, good stretchability, moderate conductivity, and remarkable self-healing properties. They were successfully used to fabricate high-quality electrode for recording electrocardiography and electromyography signals.
ACTA BIOMATERIALIA
(2022)
Article
Chemistry, Multidisciplinary
Chia-Ping Tseng, Fangxin Liu, Xu Zhang, Po-Chun Huang, Ian Campbell, Yilin Li, Joshua T. Atkinson, Tanguy Terlier, Caroline M. Ajo-Franklin, Jonathan J. Silberg, Rafael Verduzco
Summary: This article reports a novel conductive polymer coating that significantly enhances current densities in microbial bioelectronics. The coating has simple processability and can significantly increase current density when used with specific microbes.
ADVANCED MATERIALS
(2022)
Review
Engineering, Biomedical
Poppy Oldroyd, George G. Malliar
Summary: Implantable electrodes are increasingly used to treat neurological diseases, but achieving long-term stability remains a challenge. This review focuses on the key issues in the design of flexible thin-film electrodes, summarizes the common failure modes, and highlights the importance of investigating device failure.
ACTA BIOMATERIALIA
(2022)
Review
Chemistry, Multidisciplinary
Junjie Wang, Tengjiao Wang, Haoyan Liu, Kun Wang, Kumi Moses, Zhuoya Feng, Peng Li, Wei Huang
Summary: This article introduces the current research and application prospects of brain-computer interface (BCI), highlighting the limitations of traditional rigid electrodes and the advantages and development directions of flexible electrodes as alternatives. The article provides a systematic review of electrode classification, materials, fabrication methods, and requirements for flexible electrodes.
ADVANCED MATERIALS
(2023)
Article
Biotechnology & Applied Microbiology
Daiki Ando, Tetsuhiko F. Teshima, Francisco Zurita, Hu Peng, Kota Ogura, Kenji Kondo, Lennart Weiss, Ayumi Hirano-Iwata, Markus Becherer, Joe Alexander, Bernhard Wolfrum
Summary: The increasing demand for bioelectronics has led to the development of materials that can bridge the gap between electronic devices and biological tissues. Biopolymers have gained attention as next-generation materials for bioelectronics due to their high biocompatibility, biodegradability, and sustainability. However, their use has been limited by the compatibility issues with traditional fabrication methods. This study presents a fabrication process for chitosan nanofiber films integrated with conductive materials, providing a potential solution for future bioelectronic devices based on biopolymer nanofibers.
JOURNAL OF NANOBIOTECHNOLOGY
(2022)
Article
Engineering, Biomedical
Sebastian Roubert Martinez, Paul Le Floch, Jia Liu, Robert D. D. Howe
Summary: Cutaneous electrodes are commonly used for noninvasive sensing of bioelectronic signals from the brain, heart, and neuromuscular system. However, the high impedance at the tissue-to-electrode contact interface leads to a low signal-to-noise ratio. This paper introduces soft conductive polymer hydrogels made of poly(3,4-ethylenedioxy-thiophene) doped with poly(styrene sulfonate) that significantly decrease the skin-electrode contact impedance compared to clinical electrodes. Integrating these hydrogels into adhesive wearable sensors improves the fidelity of bioelectronic signals and enables applications in neural interfaces.
ADVANCED HEALTHCARE MATERIALS
(2023)
Review
Nanoscience & Nanotechnology
Fenge Lin, Wenlong Cheng
Summary: A sponge is a soft and porous material made from cellulose or synthetic polymers, which has a high surface-to-volume ratio and is mechanically deformable. It has attracted research interest for its applications in absorption, separation, catalysis, and electronics. This work discusses the recent progress in designing mechanically deformable sponge electrodes for soft electronics, including their characteristics, materials, fabrication methods, and applications.
ADVANCED ELECTRONIC MATERIALS
(2023)
Article
Engineering, Biomedical
Jiri Ehlich, Ludovico Migliaccio, Ihor Sahalianov, Marta Nikic, Jan Brodsky, Imrich Gablech, Xuan Thang Vu, Sven Ingebrandt, Eric Daniel Glowacki
Summary: The study evaluated oxygen reduction reactions (ORR) at different electrode materials and found significant differences in onset potentials and H2O2 production between materials. It concluded that typical charge-balanced biphasic pulse protocols can lead to irreversible ORR, inducing hypoxic conditions and accumulation of hydrogen peroxide near the electrode surface. These findings emphasize the importance of considering faradaic ORR in neural interface devices and highlight potential physiological consequences of hypoxia and H2O2.
JOURNAL OF NEURAL ENGINEERING
(2022)
Article
Materials Science, Multidisciplinary
Santiago Velasco-Bosom, Johannes Gurke, Sanggil Han, Michael C. Lee, George G. Malliaras
Summary: In this study, flexible and adhesive interdigitated electrodes were developed with a PEDOT:PSS coating, which improved the safety and selectivity of electrical stimulation. The effectiveness of the device was demonstrated through experiments, showing its potential as a diagnostic and monitoring tool for SFN.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Nanoscience & Nanotechnology
Tao Zhang, Yunze Liu, Fengzhi Wang, Xinhua Pan, Zhizhen Ye
Summary: This study describes a novel SnO/SnS heterojunction grown by pulsed laser deposition for high-performance transistors with changeable polarity. The operating mode of the transistor can be switched from p-type to ambipolar to n-type by growing SnS with different thicknesses on SnO with ambipolarity. The p-type mobility reached 1.77 cm(2) V-1 s(-1) and the switching ratio reached 1517. The heterojunction interface showed a high level of quality, explaining the change in working mode. Additionally, CMOS inverters were successfully used with p-type SnO transistors, n-type SnO/SnS transistors, and ambipolar transistors, providing a simple and efficient approach to prepare CMOS electrical components and a new working mode for transistors.
ADVANCED ELECTRONIC MATERIALS
(2023)
Article
Multidisciplinary Sciences
Ibrahim Momoh-Bello Omiogbemi, Danjuma Saleh Yawas, Atanu Das, Matthew Olatunde Afolayan, Emmanuel Toi Dauda, Roshan Kumar, Sudhakar Rao Gorja, Sandip Ghosh Chowdhury
Summary: This research investigates the mechanical and corrosion properties of welded duplex stainless steel structures using specially developed novel electrodes. The results show that the welded joints made with E1 electrode coated with basic flux have better mechanical properties and substantial resistance to corrosion in a 3.5% NaCl environment.
SCIENTIFIC REPORTS
(2022)
Review
Nanoscience & Nanotechnology
M. Birkholz, A. Mai, C. Wenger, C. Meliani, R. Scholz
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY
(2016)
Meeting Abstract
Chemistry, Multidisciplinary
Mario Birkholz
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES
(2015)
Article
Chemistry, Analytical
Mario Birkholz, Paul Glogener, Franziska Gloes, Thomas Basmer, Lorenz Theuer
Article
Biochemistry & Molecular Biology
Lorenz Theuer, Micha Lehmann, Stefan Junne, Peter Neubauer, Mario Birkholz
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2017)
Article
Crystallography
Mario Birkholz
Review
Biochemical Research Methods
N. Herrmann, P. Neubauer, M. Birkholz
Review
Microbiology
Vinzenz Abt, Fabian Gringel, Arum Han, Peter Neubauer, Mario Birkholz
Article
Chemistry, Analytical
Anders Henriksson, Laura Kasper, Matthias Jaeger, Peter Neubauer, Mario Birkholz
Review
Chemistry, Multidisciplinary
Anders Henriksson, Peter Neubauer, Mario Birkholz
Summary: In recent decades, alternative protocols have been developed to form bifunctional Si-C interlayers that directly bind to the silicon surface, providing more stability and reducing electric noise in biosensor devices. Despite their complexity and the need for an inert gas atmosphere, these innovative methods are predicted to expand the applications of future silicon-based biosensors.
ADVANCED MATERIALS INTERFACES
(2021)
Article
Biotechnology & Applied Microbiology
Mario Birkholz, Danai Eleni Malti, Stephan Hartmann, Peter Neubauer
Summary: This study demonstrates an electrical approach for separating lipid-producing microalgae using dielectrophoresis in a microfluidic flow cell. The method is not only suitable for process analysis, but also for strain selection of the most productive cell lines.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Engineering, Biomedical
Maria E. P. Emmerich, Anne-Sophie Sinnigen, Peter Neubauer, Mario Birkholz
Summary: Microfluidic dielectrophoretic (DEP) devices enable label-free separation and isolation of cells for clinical diagnostics and medical research. This review compares different microfluidic DEP devices and details their design and operation parameters. The technique holds promise for quick results in clinical and ambulant settings.
BIOMEDICAL MICRODEVICES
(2022)
Review
Chemistry, Analytical
Anders Henriksson, Peter Neubauer, Mario Birkholz
Summary: The performance of receptor-based biosensors is often restricted by diffusion or nonspecific bindings. Alternating current (AC) electrokinetics, which can improve mass transfer, is a growing research field. Various techniques have shown improved sensitivity and assay times by utilizing AC electrokinetics. Combining biosensors with dielectrophoresis (DEP), the AC kinetic approach with the highest selectivity, could be beneficial for specific applications if nonspecific bindings are minimized.
Proceedings Paper
Computer Science, Information Systems
Niklas P. Boldt, Danai E. Malti, Sebastian Damm, Arohi Barai, Mario Birkholz, Roland Thewes
Summary: This paper discusses the importance of correct impedance matching in dielectrophoresis experiments and compares different setups with simulations. The results show that larger electrode areas lead to a drastic decrease in separation capability for uncompensated and 50 Omega terminated setups, while the active buffer configuration exhibits proper and constant behavior.
2021 IEEE BIOMEDICAL CIRCUITS AND SYSTEMS CONFERENCE (IEEE BIOCAS 2021)
(2021)
Proceedings Paper
Computer Science, Information Systems
Alexander Frey, Niklas Boldt, Arohi Barai, Mario Birkholz, Ingo Kuehne, Roland Thewes
Summary: The Finite Element Method is utilized for modeling the voltage drop within dielectrophoresis actuators, with a focus on investigating frequency dependence. An equation for calculating the operation cut off frequency based on electrode geometry is derived. The validity of lumped element modeling is confirmed by demonstrating negligible spatial effects across actuator arrays.
2021 IEEE BIOMEDICAL CIRCUITS AND SYSTEMS CONFERENCE (IEEE BIOCAS 2021)
(2021)
Article
Engineering, Biomedical
M. Birkholz, P. Glogener, T. Basmer, F. Gloes, D. Genschow, C. Welsch, R. Ruff, K. P. Hoffmann
BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK
(2014)
Article
Materials Science, Coatings & Films
Yanchun Xie, Xiaodong Wang, Shenshen Cui, Jiali Hu, Yongcun Wei, Yi Lian, Anwu Xuan, Bin Yu, Erlin Zhang
Summary: In this study, Ti-xFe (x = 3,5,9 wt%) alloys were surface modified by micro-arc oxidation (MAO) to improve their antimicrobial properties and biocompatibility. The results showed that increasing the oxidation voltage greatly enhanced the roughness and hydrophilicity of Ti-xFe-MAO alloys. The Ti-xFe alloys micro-arc oxidized at 250 V and 300 V exhibited improved corrosion resistance and excellent antimicrobial and cytocompatibility properties, making them suitable for orthopedic implant materials.
SURFACE & COATINGS TECHNOLOGY
(2024)
Article
Materials Science, Coatings & Films
Yuting Hao, Zuoyan Ye, Lili Wang, Minheng Ye, Hui Dong, Chao Wang, Yunchen Du
Summary: This study focuses on the modification of PEO coatings on Ta-12W alloy using NH4F additive. The results show that ultra-low porosity coatings can be prepared by optimizing the NH4F content. The formation process of specific structures on the coating surface is discussed, and the effects of NH4F concentration and treatment duration on coating characteristics are investigated.
SURFACE & COATINGS TECHNOLOGY
(2024)
Article
Materials Science, Coatings & Films
Yuanzhuo Liu, Linjiang Chai, Tao Yang, Chaodan Hu, Chuanmei Wang, Guoqiang Xi
Summary: By employing a pulsed laser, laser cladding was performed on IN718 alloy pre-coated with CrCoNi-TiC/SiC powders and three defect-free coatings were successfully prepared. The addition of TiC and SiC powders generated fine carbides dispersed in the coatings and led to changes in grain and substructure morphologies, resulting in increased hardness and wear resistance.
SURFACE & COATINGS TECHNOLOGY
(2024)
Article
Materials Science, Coatings & Films
M. Ghaemi, A. Lopez-Cazalilla, K. Sarakinos, G. J. Rosaz, C. P. A. Carlos, S. Leith, S. Calatroni, M. Himmerlich, F. Djurabekova
Summary: The use of high-power impulse magnetron sputtering can result in dense and uniform niobium films on all surfaces of superconducting rf cavities, as simulated and investigated in this study.
SURFACE & COATINGS TECHNOLOGY
(2024)
Article
Materials Science, Coatings & Films
Jiaheng Du, Xinli Fan, Dongqin Xiao, Wuxiang Wang, Yiran Yin, Zhong Li, Kui He, Yanfei Tan, Jiyuan Yan, Gangli Liu, Ke Duan
Summary: This study investigated the electrophoretic deposition (EPD) of magnesium oxide (MgO) coatings on micro-arc oxidized titanium (MAO-Ti) and evaluated their in vitro antibacterial properties and biocompatibility. The results showed that MgO coatings significantly reduced bacterial numbers and biofilm formation, while also demonstrating good cytocompatibility and induction of osteoblast mineralization.
SURFACE & COATINGS TECHNOLOGY
(2024)
Article
Materials Science, Coatings & Films
Samiksha Moharana, Yuichi Otsuka, R. Gnanamoorthy
Summary: The addition of titania to HAp coatings improves their wear resistance and reduces damage to titanium implants caused by debris generation. This study evaluates the fretting wear resistance of titania-added HAp suspension plasma spray coating and finds that it exhibits reduced friction coefficient and increased wear resistance.
SURFACE & COATINGS TECHNOLOGY
(2024)
Article
Materials Science, Coatings & Films
Li-Ping Wu
Summary: The functional hazenite coating deposited on AZ31 Mg alloy showed improved roughness and hydrophilicity, enhanced biocompatibility, reduced degradation rate, and decreased susceptibility to stress corrosion cracking.
SURFACE & COATINGS TECHNOLOGY
(2024)
Article
Materials Science, Coatings & Films
Ning Tian, Delei Xu, Jinfei Wei, Bucheng Li, Junping Zhang
Summary: This study reports the preparation of a superhydrophobic and anti-bacterial fabric for face masks. The fabric exhibits high superhydrophobicity and excellent moisture resistance, enabling functionality effectiveness in cold weather conditions. The fabric also demonstrates remarkable anti-bacterial activity against E. coli, attributed to the synergistic effect of superhydrophobicity and embedded ZnO nanoparticles. This superhydrophobic anti-bacterial fabric holds great potential for various practical applications in personal protective equipment, healthcare, and disease prevention.
SURFACE & COATINGS TECHNOLOGY
(2024)
Article
Materials Science, Coatings & Films
Katharina Beck, Anke S. Ulrich, Andreas K. Czerny, Emma M. H. White, Martin Heilmaier, Mathias C. Galetz
Summary: Refractory metal based alloys have great potential as structural materials for high-temperature applications due to their high melting points. However, they are prone to catastrophic oxidation at around 700 degrees C. This study investigated the effect of aluminium diffusion coatings on the oxidation resistance of pure molybdenum, niobium, tantalum, and tungsten. The results showed that the aluminization improved the oxidation behavior and decreased the oxide growth rate for molybdenum and tantalum.
SURFACE & COATINGS TECHNOLOGY
(2024)
Article
Materials Science, Coatings & Films
Wenwen Shuai, Haijun Dou, Zhichen Guan, Wei Qian, Zhibao Li, Yinqun Hua, Jie Cai
Summary: This study synthesized (Y1-xLax)3Al5O12 (x = 0, 0.1, 0.2, 0.3) materials by doping lanthanum ions, and found that the doped materials exhibited improved mechanical properties and thermal expansion coefficient, as well as enhanced resistance to CMAS corrosion. These materials have potential applications.
SURFACE & COATINGS TECHNOLOGY
(2024)
Article
Materials Science, Coatings & Films
Xianglei Liu, Jiahui Ding, Wanbo Hou, Xinhao Shi, Tao Feng, Xiangyuan Meng, Shifeng Wen, Mingde Tong, Zhufeng Yue
Summary: A composite coating was developed to improve the adhesion, wear resistance, and corrosion resistance, which exhibited significant enhancements in these properties.
SURFACE & COATINGS TECHNOLOGY
(2024)
Article
Materials Science, Coatings & Films
Hongxuan Xing, Jidong Li, Xianwei Hu, Liang Tian, Renyun Zhang, Yiyong Wang
Summary: By depositing a Cu/Co-Mo corrosion-resistant plating layer on the surface of 6061 Al alloy, the bonding strength between the alloy and the plating layer can be improved and the corrosion resistance can be enhanced. The composite coating forms an obvious three-layer structure with Co-Mo coating exhibiting amorphous characteristics and Co3Mo phase composition. The composite coating improves the corrosion resistance and hardness of the substrate, effectively protecting the 6061 Al alloy.
SURFACE & COATINGS TECHNOLOGY
(2024)
Article
Materials Science, Coatings & Films
Fan Yang, Debin Wang, Tianrun Li, Baijun Yang, Suode Zhang, Jianqiang Wang
Summary: The impact-corrosion behavior of monolayer and hierarchical Fe-based amorphous coatings fabricated by HVAF was investigated in 3.5 wt% NaCl solution. The monolayer coating exhibits corrosion failure with increased impact energy, while the hierarchical coating shows improved resistance. However, at high impact energies, both coatings experience corrosion degradation.
SURFACE & COATINGS TECHNOLOGY
(2024)
Article
Materials Science, Coatings & Films
Shoaib Ahmad, Muddasir Nawaz, Solaiman Mohammad, R. A. Shakoor, Ramazan Kahraman, Talal Mohammed Al Tahtamouni
Summary: This research presents a novel self-healing anti-corrosion composite coating that demonstrates higher inhibition efficiency and self-healing effect, providing protection for metallic structures against corrosive environments.
SURFACE & COATINGS TECHNOLOGY
(2024)
Article
Materials Science, Coatings & Films
Hui-Wen Peng, Chun-Hway Hsueh
Summary: A series of (CoCrNi)100-x-ySixNdy medium entropy alloy films with manipulated metalloid element, Si, and rare earth element, Nd, were synthesized using magnetron three-target co-sputtering. The films showed different structures and mechanical properties with varying Si and Nd contents. The optimized mechanical properties were observed in the film with Si0.61Nd5.14, attributed to precipitation strengthening and grain refinement.
SURFACE & COATINGS TECHNOLOGY
(2024)