Inhibiting, promoting, and preserving stability of functional proteinfibrils

Reversible Heat-Induced Dissociation of β2-Microglobulin Amyloid Fibrils

(2011) József Kardos et al.   BIOCHEMISTRY

Protein–surfactant interactions: A tale of many states

(2011) Daniel Otzen   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Complexation of β-Lactoglobulin Fibrils and Sulfated Polysaccharides

(2011) Owen G. Jones et al.   BIOMACROMOLECULES

Perturbation of the Stability of Amyloid Fibrils through Alteration of Electrostatic Interactions

(2011) Sarah L. Shammas et al.   BIOPHYSICAL JOURNAL

What Drives Amyloid Molecules To Assemble into Oligomers and Fibrils?

(2011) Jeremy D. Schmit et al.   BIOPHYSICAL JOURNAL

Prediction of the aggregation propensity of proteins from the primary sequence: Aggregation properties of proteomes

(2011) Virginia Castillo et al.   Biotechnology Journal

New biocompatible thermo-reversible hydrogels from PNiPAM-decorated amyloid fibrils

(2011) Chaoxu Li et al.   CHEMICAL COMMUNICATIONS

Encapsulation systems based on ovalbumin fibrils and high methoxyl pectin

(2011) K.N.P. Humblet-Hua et al.   FOOD HYDROCOLLOIDS

Amyloid-mediated synthesis of giant, fluorescent, gold single crystals and their hybrid sandwiched composites driven by liquid crystalline interactions

(2011) Sreenath Bolisetty et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Probing Amyloid-Beta Fibril Stability by Increasing Ionic Strengths

(2011) Jernej Zidar et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Self-Assembly of Short Aβ(16−22) Peptides: Effect of Terminal Capping and the Role of Electrostatic Interaction

(2011) Kai Tao et al.   LANGMUIR

Nanomechanics of functional and pathological amyloid materials

(2011) Tuomas P. J. Knowles et al.   Nature Nanotechnology

Elucidation of the binding sites of sodium dodecyl sulfate to β-lactoglobulin using hydrogen/deuterium exchange mass spectrometry combined with docking simulation

(2011) Wenbing Hu et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

A supramolecular bottle-brush approach to disassemble amyloid fibrils

(2011) Patrick A. Rühs et al.   Soft Matter

Unravelling adsorption and alignment of amyloid fibrils at interfaces by probe particle tracking

(2011) Lucio Isa et al.   Soft Matter

Adjustable twisting periodic pitch of amyloid fibrils

(2011) Jozef Adamcik et al.   Soft Matter

The effect of curcumin on human islet amyloid polypeptide misfolding and toxicity

(2010) Marie Daval et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Neuroprotective Multifunctional Iron Chelators: From Redox-Sensitive Process to Novel Therapeutic Opportunities

(2010) Orly Weinreb et al.   ANTIOXIDANTS & REDOX SIGNALING

ATP-induced noncooperative thermal unfolding of hen lysozyme

(2010) Honglin Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Amino acid sequence determinants and molecular chaperones in amyloid fibril formation

(2010) Charlotte Nerelius et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Flavanol (−)-Epigallocatechin 3-Gallate Inhibits Amyloid Formation by Islet Amyloid Polypeptide, Disaggregates Amyloid Fibrils, and Protects Cultured Cells against IAPP-Induced Toxicity

(2010) Fanling Meng et al.   BIOCHEMISTRY

Detailed Biophysical Characterization of the Acid-Induced PrPcto PrPβConversion Process

(2010) Trent C. Bjorndahl et al.   BIOCHEMISTRY

Disassembly and Reassembly of Amyloid Fibrils in Water−Ethanol Mixtures

(2010) Sophia Jordens et al.   BIOMACROMOLECULES

Fibrillar peptide gels in biotechnology and biomedicine

(2010) Jangwook P. Jung et al.   BIOPOLYMERS

Strategies for the Inhibition of Protein Aggregation in Human Diseases

(2010) Manuela Bartolini et al.   CHEMBIOCHEM

Amyloid Assemblies: Protein Legos at a Crossroads in Bottom-Up Synthetic Biology

(2010) Rafael Giraldo   CHEMBIOCHEM

End-stapled homo and hetero collagen triple helices: a click chemistry approach

(2010) Cillian Byrne et al.   CHEMICAL COMMUNICATIONS

Ionic liquids: a pathway to environmental acceptability

(2010) Marija Petkovic et al.   CHEMICAL SOCIETY REVIEWS

The transition metals copper and iron in neurodegenerative diseases

(2010) Susana Rivera-Mancía et al.   CHEMICO-BIOLOGICAL INTERACTIONS

REVIEW: Curcumin and Alzheimer's Disease

(2010) Tsuyoshi Hamaguchi et al.   CNS Neuroscience & Therapeutics

Investigating the effects of sodium dodecyl sulfate on the aggregative behavior of hen egg-white lysozyme at acidic pH

(2010) Ying-Tz Hung et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Amyloid Formation in Surfactants and Alcohols: Membrane Mimetics or Structural Switchers?

(2010) Daniel E. Otzen   CURRENT PROTEIN & PEPTIDE SCIENCE

Alzheimer's disease amyloid hypothesis at crossroads: where do we go from here?

(2010) Uday Saxena   EXPERT OPINION ON THERAPEUTIC TARGETS

Inhibition of aggregate formation as therapeutic target in protein misfolding diseases: effect of tetracycline and trehalose

(2010) Ivana Sirangelo et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Molecular insights into amyloid regulation by membrane cholesterol and sphingolipids: common mechanisms in neurodegenerative diseases

(2010) Jacques Fantini et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Modulation of Aβ42 fibrillogenesis by glycosaminoglycan structure

(2010) Juan José Valle-Delgado et al.   FASEB JOURNAL

Mysterious oligomerization of the amyloidogenic proteins

(2010) Vladimir N. Uversky   FEBS Journal

Polyglutamine shows a urea-like affinity for unfolded cytosolic protein

(2010) Jeremy L. England et al.   FEBS LETTERS

Nucleic acid induced protein aggregation and its role in biology and pathology

(2010) Jun Yin   Frontiers in Bioscience-Landmark

Tuning the properties of β-lactoglobulin nanofibrils with pH, NaCl and CaCl2

(2010) S.M. Loveday et al.   INTERNATIONAL DAIRY JOURNAL

In Vitro Digestion of β-Lactoglobulin Fibrils Formed by Heat Treatment at Low pH

(2010) Libei Bateman et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Iron Promotes the Toxicity of Amyloid β Peptide by Impeding Its Ordered Aggregation

(2010) Beinan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Molecular Basis of Distinct Aggregation Pathways of Islet Amyloid Polypeptide

(2010) Lei Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol Selectively Remodels Soluble Oligomers and Fibrils of Amyloid Aβ into Off-pathway Conformers

(2010) Ali Reza A. Ladiwala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Folding and Fibrillogenesis: Clues from β2-Microglobulin

(2010) Enrico Rennella et al.   JOURNAL OF MOLECULAR BIOLOGY

Iron chelation and neuroprotection in neurodegenerative diseases

(2010) Xuping Li et al.   JOURNAL OF NEURAL TRANSMISSION

Role of proteoglycans and glycosaminoglycans in the pathogenesis of Alzheimer's disease and related disorders: Amyloidogenesis and therapeutic strategies-A review

(2010) Toshio Ariga et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The Thermodynamic Stability of Amyloid Fibrils Studied by Differential Scanning Calorimetry

(2010) Bertrand Morel et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Fibrillation of β-Lactoglobulin at Low pH in the Presence of a Complexing Anionic Polysaccharide

(2010) Owen G. Jones et al.   LANGMUIR

Metals, oxidative stress and neurodegenerative disorders

(2010) Klaudia Jomova et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Nutraceutical Antioxidants as Novel Neuroprotective Agents

(2010) Natalie A. Kelsey et al.   MOLECULES

Natural products as a source of Alzheimer's drug leads

(2010) Philip Williams et al.   NATURAL PRODUCT REPORTS

Understanding amyloid aggregation by statistical analysis of atomic force microscopy images

(2010) Jozef Adamcik et al.   Nature Nanotechnology

Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

(2010) Lars M. Ittner et al.   NATURE REVIEWS NEUROSCIENCE

A study of alcohol-induced gelation of β-lactoglobulin with small-angle neutron scattering, neutron spin echo, and dynamic light scattering measurements

(2010) Koji Yoshida et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Patterns of protein unfolding and protein aggregation in ionic liquids

(2010) Diana Constatinescu et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Structural polymorphism of Alzheimer Aβ and other amyloid fibrils

(2010) Marcus Fändrich et al.   Prion

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

(2010) Jan Bieschke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid protofilament formation of hen egg lysozyme in highly concentrated ethanol solution

(2010) Shuichiro Goda et al.   PROTEIN SCIENCE

Structurally distinct toxicity inhibitors bind at common loci on β-amyloid fibril

(2010) Ben Keshet et al.   PROTEIN SCIENCE

Biology of Amyloid: Structure, Function, and Regulation

(2010) Jason Greenwald et al.   STRUCTURE

The intricate mechanisms of neurodegeneration in prion diseases

(2010) Claudio Soto et al.   TRENDS IN MOLECULAR MEDICINE

Phenolic Compounds Prevent Alzheimer’s Pathology through Different Effects on the Amyloid-β Aggregation Pathway

(2009) Tsuyoshi Hamaguchi et al.   AMERICAN JOURNAL OF PATHOLOGY

β2-microglobulin: from physiology to amyloidosis

(2009) Niels H. H. Heegaard   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Binding and stabilization of transthyretin by curcumin

(2009) Raghu Pullakhandam et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Aluminium neurotoxicity: neurobehavioural and oxidative aspects

(2009) Vijay Kumar et al.   ARCHIVES OF TOXICOLOGY

Inhibition of Amyloid Formation by Ionic Liquids: Ionic Liquids Affecting Intermediate Oligomers

(2009) Hamid Reza Kalhor et al.   BIOMACROMOLECULES

Effect of curcumin on the amyloid fibrillogenesis of hen egg-white lysozyme

(2009) Steven S.-S. Wang et al.   BIOPHYSICAL CHEMISTRY

Amyloid Fibril-Like Structure Underlies the Aggregate Structure across the pH Range for β -Lactoglobulin

(2009) Mark R.H. Krebs et al.   BIOPHYSICAL JOURNAL

Inhibiting Islet Amyloid Polypeptide Fibril Formation by the Red Wine Compound Resveratrol

(2009) Rajesh Mishra et al.   CHEMBIOCHEM

Formation and dissolution of hen egg white lysozyme amyloid fibrils in protic ionic liquids

(2009) Nolene Byrne et al.   CHEMICAL COMMUNICATIONS

Particle tracking microrheology of gel-forming amyloid fibril networks

(2009) A. M. Corrigan et al.   EUROPEAN PHYSICAL JOURNAL E

Amyloid-β fibrillogenesis: Structural insight and therapeutic intervention

(2009) Kevin A. DaSilva et al.   EXPERIMENTAL NEUROLOGY

Unique copper-induced oligomers mediate alpha-synuclein toxicity

(2009) Josephine A. Wright et al.   FASEB JOURNAL

Cold-set thickening mechanism of β-lactoglobulin at low pH: Concentration effects

(2009) P. Mudgal et al.   FOOD HYDROCOLLOIDS

Tea Catechins Induce the Conversion of Preformed Lysozyme Amyloid Fibrils to Amorphous Aggregates

(2009) Jing He et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Globular Tetramers of β2-Microglobulin Assemble into Elaborate Amyloid Fibrils

(2009) Helen E. White et al.   JOURNAL OF MOLECULAR BIOLOGY

(−)-Epigallocatechin-3-Gallate (EGCG) Maintains κ-Casein in Its Pre-Fibrillar State without Redirecting Its Aggregation Pathway

(2009) Sean A. Hudson et al.   JOURNAL OF MOLECULAR BIOLOGY

Photocontrol of β-Amyloid Peptide (1−40) Fibril Growth in the Presence of a Photosurfactant

(2009) Andrea C. Hamill et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Liquid Crystalline Phase Behavior of Protein Fibers in Water: Experiments versus Theory

(2009) Jin-Mi Jung et al.   LANGMUIR

Metal Ion Physiopathology in Neurodegenerative Disorders

(2009) Silvia Bolognin et al.   NEUROMOLECULAR MEDICINE

Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation

(2009) Ying Feng et al.   NEUROTOXICOLOGY

Prions: Protein Aggregation and Infectious Diseases

(2009) Adriano Aguzzi et al.   PHYSIOLOGICAL REVIEWS

Ultrasonication-dependent production and breakdown lead to minimum-sized amyloid fibrils

(2009) E. Chatani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 -Helix targeting reduces amyloid-  peptide toxicity

(2009) C. Nerelius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shear flow promotes amyloid-  fibrilization

(2009) D. E. Dunstan et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules

(2009) S. K. Maji et al.   SCIENCE

Shear-induced structure and mechanics of β-lactoglobulin amyloid fibrils

(2009) Dave E. Dunstan et al.   Soft Matter

Amyloids: Not Only Pathological Agents but Also Ordered Nanomaterials

(2008) Izhack Cherny et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In vivo prion protein intestinal uptake in fish

(2008) ANDREA ZENONE DALLA VALLE et al.   APMIS

Surface-enhanced nucleation of insulin amyloid fibrillation

(2008) Arpan Nayak et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Characterization of amyloidogenesis of hen egg lysozyme in concentrated ethanol solution

(2008) Mikel Holley et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Influence of Multiple Metal Ions on β-Amyloid Aggregation and Dissociation on a Solid Surface†

(2008) Jungki Ryu et al.   BIOCHEMISTRY

Phenolsulfonphthalein, but Not Phenolphthalein, Inhibits Amyloid Fibril Formation: Implications for the Modulation of Amyloid Self-Assembly†

(2008) Michal Levy et al.   BIOCHEMISTRY

Peptides are Building Blocks of Heat-Induced Fibrillar Protein Aggregates of β-Lactoglobulin Formed at pH 2

(2008) Cynthia Akkermans et al.   BIOMACROMOLECULES

Structure of Heat-Induced β-Lactoglobulin Aggregates and their Complexes with Sodium-Dodecyl Sulfate

(2008) Jin-Mi Jung et al.   BIOMACROMOLECULES

Organic solvent mediated self-association of an amyloid forming peptide from β2-microglobulin: An atomic force microscopy study

(2008) Nitin Chaudhary et al.   BIOPOLYMERS

Thermally induced denaturation and aggregation of BLG-A: effect of the Cu2+ and Zn2+ metal ions

(2008) A. Stirpe et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Surfactant-induced conformational transition of amyloid β-peptide

(2008) N. Sureshbabu et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Sulfated Polysaccharides Promote the Assembly of Amyloid β1–42 Peptide into Stable Fibrils of Reduced Cytotoxicity

(2008) Ramona Bravo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational Stability of PrP Amyloid Fibrils Controls Their Smallest Possible Fragment Size

(2008) Ying Sun et al.   JOURNAL OF MOLECULAR BIOLOGY

Competition between Folding, Native-State Dimerisation and Amyloid Aggregation in β-Lactoglobulin

(2008) Daizo Hamada et al.   JOURNAL OF MOLECULAR BIOLOGY

Green tea extracts interfere with the stress-protective activity of PrPCand the formation of PrPSc

(2008) Angelika S. Rambold et al.   JOURNAL OF NEUROCHEMISTRY

Fibril aggregation inhibitory activity of the β-sheet breaker peptides: a molecular docking approach

(2008) Maria Giovanna Chini et al.   JOURNAL OF PEPTIDE SCIENCE

Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease

(2008) A. N. Begum et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Micellization of Surfactin and Its Effect on the Aggregate Conformation of Amyloid β(1-40)

(2008) Yuchun Han et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Polymer Microcapsules with a Fiber-Reinforced Nanocomposite Shell

(2008) Leonard M. C. Sagis et al.   LANGMUIR

Amyloid formation by globular proteins under native conditions

(2008) Fabrizio Chiti et al.   Nature Chemical Biology

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

(2008) Dagmar E Ehrnhoefer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Neuroprotective Properties of Glycosaminoglycans: Potential Treatment for Neurodegenerative Disorders

(2008) B. Dudas et al.   Neurodegenerative Diseases

Structural requirements for the flavonoid fisetin in inhibiting fibril formation of amyloid β protein

(2008) Tatsuhiro Akaishi et al.   NEUROSCIENCE LETTERS

Amyloid fibrils: modulation of formation and structure by copper(ii)

(2008) Vincent Pradines et al.   NEW JOURNAL OF CHEMISTRY

Aggregation and Amyloid Fibril Formation of the Prion Protein Is Accelerated in the Presence of Glycogen

(2008) Giannantonio Panza et al.   REJUVENATION RESEARCH

Polyglutamine neurodegeneration: protein misfolding revisited

(2008) Aislinn J. Williams et al.   TRENDS IN NEUROSCIENCES

Folding versus aggregation: Polypeptide conformations on competing pathways

(2007) Thomas R. Jahn et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Potential pathogenic role of β-amyloid1–42–aluminum complex in Alzheimer's disease

(2007) Denise Drago et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Islet Amyloid Polypeptide Forms Rigid Lipid–Protein Amyloid Fibrils on Supported Phospholipid Bilayers

(2007) Yegor A. Domanov et al.   JOURNAL OF MOLECULAR BIOLOGY

Phospholipid Interaction Induces Molecular-level Polymorphism in Apolipoprotein C-II Amyloid Fibrils via Alternative Assembly Pathways

(2007) Michael D.W. Griffin et al.   JOURNAL OF MOLECULAR BIOLOGY

Sonication of proteins causes formation of aggregates that resemble amyloid

(2004) Peter B. Stathopulos et al.   PROTEIN SCIENCE

A kinetic study of β-lactoglobulin amyloid fibril formation promoted by urea

(2002) Daizo Hamada et al.   PROTEIN SCIENCE