Functionalization of Carbon Nanoparticles Modulates Inflammatory Cell Recruitment and NLRP3 Inflammasome Activation

Understanding the Toxicity of Carbon Nanotubes

(2012) Ying Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Nanotools for the Delivery of Antimicrobial Peptides

(2012) Patricia Urban et al.   CURRENT DRUG TARGETS

Recent progress and perspectives on the toxicity of carbon nanotubes at organism, organ, cell, and biomacromolecule levels

(2012) Xingchen Zhao et al.   ENVIRONMENT INTERNATIONAL

Comparison of cytotoxic and inflammatory responses of pristine and functionalized multi-walled carbon nanotubes in RAW 264.7 mouse macrophages

(2012) Ting Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components

(2012) Sarah L Doyle et al.   NATURE MEDICINE

Polymyxin B Inadequately Quenches the Effects of Contaminating Lipopolysaccharide on Murine Dendritic Cells

(2012) Graham A. Tynan et al.   PLoS One

Long, Needle-like Carbon Nanotubes and Asbestos Activate the NLRP3 Inflammasome through a Similar Mechanism

(2011) Jaana Palomäki et al.   ACS Nano

Synthesis and Characterization of Boron Azadipyrromethene Single-Wall Carbon Nanotube Electron Donor−Acceptor Conjugates

(2011) Kevin Flavin et al.   ACS Nano

Direct Effects of Carbon Nanotubes on Dendritic Cells Induce Immune Suppression Upon Pulmonary Exposure

(2011) Alexey V. Tkach et al.   ACS Nano

Nanographite Impurities in Carbon Nanotubes: Their Influence on the Oxidation of Insulin, Nitric Oxide, and Extracellular Thiols

(2011) Elaine Lay Khim Chng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Controlled carboxylic acid introduction: a route to highly purified oxidised single-walled carbon nanotubes

(2011) Kevin Flavin et al.   JOURNAL OF MATERIALS CHEMISTRY

Hydroxyapatite-anatase-carbon nanotube nanocomposite coatings fabricated by electrophoretic codeposition for biomedical applications

(2011) Bokai Zhang et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Double-walled carbon nanotubes trigger IL-1β release in human monocytes through Nlrp3 inflammasome activation

(2011) Etienne Meunier et al.   Nanomedicine-Nanotechnology Biology and Medicine

Carbon Nano-onions for Imaging the Life Cycle of Drosophila Melanogaster

(2011) Mitrajit Ghosh et al.   Small

Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes

(2011) Samuele Calabro et al.   VACCINE

[Gd@C82(OH)22]n Nanoparticles Induce Dendritic Cell Maturation and Activate Th1 Immune Responses

(2010) De Yang et al.   ACS Nano

Aluminum adjuvants elicit fibrin-dependent extracellular traps in vivo

(2010) M. W. Munks et al.   BLOOD

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Critical Investigation of Defect Site Functionalization on Single-Walled Carbon Nanotubes

(2010) Elisa Del Canto et al.   CHEMISTRY OF MATERIALS

Repeated pulmonary exposure to single-walled carbon nanotubes exacerbates allergic inflammation of the airway: Possible role of oxidative stress

(2010) Ken-ichiro Inoue et al.   FREE RADICAL BIOLOGY AND MEDICINE

Carbon Nanotube-Based Nanocarriers: The Importance of Keeping It Clean

(2010) Lucia G. Delogu et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Low-toxic and safe nanomaterials by surface-chemical design, carbon nanotubes, fullerenes, metallofullerenes, and graphenes

(2010) Liang Yan et al.   Nanoscale

Endotoxin contamination of engineered nanomaterials

(2010) R. Keith Esch et al.   Nanotoxicology

Functionalization of Multilayer Fullerenes (Carbon Nano-Onions) using Diazonium Compounds and “Click” Chemistry

(2010) Kevin Flavin et al.   ORGANIC LETTERS

Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1  and IL-1 

(2010) A. S. Yazdi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carbon nanotubes induce inflammation but decrease the production of reactive oxygen species in lung

(2010) D. Crouzier et al.   TOXICOLOGY

A comparison of acute and long-term effects of industrial multiwalled carbon nanotubes on human lung and immune cells in vitro

(2010) Tina Thurnherr et al.   TOXICOLOGY LETTERS

Pneumolysin Activates the NLRP3 Inflammasome and Promotes Proinflammatory Cytokines Independently of TLR4

(2010) Edel A. McNeela et al.   PLoS Pathogens

Carbon nanotubes in biology and medicine: In vitro and in vivo detection, imaging and drug delivery

(2009) Zhuang Liu et al.   Nano Research

Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome

(2009) Fiona A. Sharp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineered nanomaterials cause cytotoxicity and activation on mouse antigen presenting cells

(2009) J. Palomäki et al.   TOXICOLOGY

Size-dependent toxicity of metal oxide particles—A comparison between nano- and micrometer size

(2009) Hanna L. Karlsson et al.   TOXICOLOGY LETTERS

Colloidal Properties of Aqueous Suspensions of Acid-Treated, Multi-Walled Carbon Nanotubes

(2008) Billy Smith et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Special regulatory T-cell review: FOXP3 biochemistry in regulatory T cells – how diverse signals regulate suppression

(2008) Bin Li et al.   IMMUNOLOGY

Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition

(2008) Hui Yang et al.   JOURNAL OF APPLIED TOXICOLOGY

Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

(2008) Mirjam Kool et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY

A pilot toxicology study of single-walled carbon nanotubes in a small sample of mice

(2008) Meike L. Schipper et al.   Nature Nanotechnology