Role of Interleukin-1 Inhibitors in Osteoarthritis

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

(2011) C. A. Dinarello   BLOOD

New drugs beyond biologics in rheumatoid arthritis: the kinase inhibitors

(2011) M. G. Bonilla-Hernan et al.   RHEUMATOLOGY

A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee

(2011) Stanley B Cohen et al.   ARTHRITIS RESEARCH & THERAPY

Anticytokine Therapy for Osteoarthritis

(2010) Charles J. Malemud   DRUGS & AGING

Getting arthritis gene therapy into the clinic

(2010) Christopher H. Evans et al.   Nature Reviews Rheumatology

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

(2010) Mohit Kapoor et al.   Nature Reviews Rheumatology

Erosive osteoarthritis of the hand: clinical experience with anakinra

(2009) L Bacconnier et al.   ANNALS OF THE RHEUMATIC DISEASES

Intraarticular injection of anakinra in osteoarthritis of the knee: A multicenter, randomized, double-blind, placebo-controlled study

(2009) X. Chevalier et al.   ARTHRITIS AND RHEUMATISM

Efficacy and safety of diacerein in early knee osteoarthritis: a randomized placebo-controlled trial

(2009) Ballari Brahmachari et al.   CLINICAL RHEUMATOLOGY

Safety, Tolerability, and Clinical Outcomes after Intraarticular Injection of a Recombinant Adeno-associated Vector Containing a Tumor Necrosis Factor Antagonist Gene: Results of a Phase 1/2 Study

(2009) P. J. MEASE et al.   JOURNAL OF RHEUMATOLOGY

Symptomatic efficacy and safety of diacerein in the treatment of osteoarthritis: a meta-analysis of randomized placebo-controlled trials

(2009) E.M. Bartels et al.   OSTEOARTHRITIS AND CARTILAGE

The placebo effect and its determinants in osteoarthritis: meta-analysis of randomised controlled trials

(2008) W Zhang et al.   ANNALS OF THE RHEUMATIC DISEASES

Autologous conditioned serum (Orthokine) is an effective treatment for knee osteoarthritis

(2008) A.W.A. Baltzer et al.   OSTEOARTHRITIS AND CARTILAGE

Autologous interleukin-1 receptor antagonist improves function and symptoms in osteoarthritis when compared to placebo in a prospective randomized controlled trial

(2007) K.G. Auw Yang et al.   OSTEOARTHRITIS AND CARTILAGE