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Title
B cells in MS and NMO: pathogenesis and therapy
Authors
Keywords
Multiple sclerosis, Neuromyelitis optica, B cells, Antibodies, Pathogenesis, Therapy
Journal
Seminars in Immunopathology
Volume 36, Issue 3, Pages 339-350
Publisher
Springer Nature
Online
2014-05-16
DOI
10.1007/s00281-014-0424-x
References
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Note: Only part of the references are listed.- Cerebrospinal Fluid IL-21 Levels in Neuromyelitis Optica and Multiple Sclerosis
- (2014) Aimin Wu et al. CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
- IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases
- (2014) Ping Shen et al. NATURE
- Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica
- (2013) Tatsuro Misu et al. ACTA NEUROPATHOLOGICA
- Immunoadsorption in steroid-refractory multiple sclerosis: Clinical experience in 60 patients
- (2013) Franz Heigl et al. ATHEROSCLEROSIS SUPPLEMENTS
- Expansion of CD27high plasmablasts in transverse myelitis patients that utilize VH4 and JH6 genes and undergo extensive somatic hypermutation
- (2013) A J Ligocki et al. GENES AND IMMUNITY
- Specific peripheral B cell tolerance defects in patients with multiple sclerosis
- (2013) Tuure Kinnunen et al. JOURNAL OF CLINICAL INVESTIGATION
- IL-21 and CD40L Synergistically Promote Plasma Cell Differentiation through Upregulation of Blimp-1 in Human B Cells
- (2013) B. B. Ding et al. JOURNAL OF IMMUNOLOGY
- Distinction and Temporal Stability of Conformational Epitopes on Myelin Oligodendrocyte Glycoprotein Recognized by Patients with Different Inflammatory Central Nervous System Diseases
- (2013) M. C. Mayer et al. JOURNAL OF IMMUNOLOGY
- Exacerbation of experimental autoimmune encephalomyelitis by passive transfer of IgG antibodies from a multiple sclerosis patient responsive to immunoadsorption
- (2013) Rosetta Pedotti et al. JOURNAL OF NEUROIMMUNOLOGY
- Glycine receptor and myelin oligodendrocyte glycoprotein antibodies in Turkish patients with neuromyelitis optica
- (2013) Mark Woodhall et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Eculizumab in AQP4-IgG-positive relapsing neuromyelitis optica spectrum disorders: an open-label pilot study
- (2013) Sean J Pittock et al. LANCET NEUROLOGY
- The utility of cerebrospinal fluid analysis in patients with multiple sclerosis
- (2013) Martin Stangel et al. Nature Reviews Neurology
- The spectrum of MOG autoantibody-associated demyelinating diseases
- (2013) Markus Reindl et al. Nature Reviews Neurology
- Aquaporin water channels in the nervous system
- (2013) Marios C. Papadopoulos et al. NATURE REVIEWS NEUROSCIENCE
- Anti-Aquaporin-1 Autoantibodies in Patients with Neuromyelitis Optica Spectrum Disorders
- (2013) John S. Tzartos et al. PLoS One
- BAFF Controls Neural Cell Survival through BAFF Receptor
- (2013) Satoru Tada et al. PLoS One
- Interleukin-6 contributes to CNS axon regeneration upon inflammatory stimulation
- (2013) M Leibinger et al. Cell Death & Disease
- Interleukin 6 Receptor Blockade in Patients With Neuromyelitis Optica Nonresponsive to Anti-CD20 Therapy
- (2013) Ilya Ayzenberg et al. JAMA Neurology
- Intrastriatal injection of interleukin-1 beta triggers the formation of neuromyelitis optica-like lesions in NMO-IgG seropositive rats
- (2013) Maja Kitic et al. Acta Neuropathologica Communications
- Neuromyelitis optica IgG and natural killer cells produce NMO lesions in mice without myelin loss
- (2012) Julien Ratelade et al. ACTA NEUROPATHOLOGICA
- Enzymatic deglycosylation converts pathogenic neuromyelitis optica anti-aquaporin-4 immunoglobulin G into therapeutic antibody
- (2012) Lukmanee Tradtrantip et al. ANNALS OF NEUROLOGY
- Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognizeClostridiumABC transporter
- (2012) Michel Varrin-Doyer et al. ANNALS OF NEUROLOGY
- Anti–Myelin Oligodendrocyte Glycoprotein Antibodies in Pediatric Patients With Optic Neuritis
- (2012) Kevin Rostasy et al. ARCHIVES OF NEUROLOGY
- Antibody-independent B cell effector functions in relapsing remitting Multiple Sclerosis: Clues to increased inflammatory and reduced regulatory B cell capacity
- (2012) Sara J. Ireland et al. AUTOIMMUNITY
- Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis
- (2012) Christina Elliott et al. BRAIN
- Identifying autoantigens in demyelinating diseases
- (2012) Tobias Derfuss et al. CURRENT OPINION IN NEUROLOGY
- IL-6 promotes regeneration and functional recovery after cortical spinal tract injury by reactivating intrinsic growth program of neurons and enhancing synapse formation
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- Small-molecule inhibitors of NMO-IgG binding to aquaporin-4 reduce astrocyte cytotoxicity in neuromyelitis optica
- (2012) Lukmanee Tradtrantip et al. FASEB JOURNAL
- Lipid-Antigen Presentation by CD1d+ B Cells Is Essential for the Maintenance of Invariant Natural Killer T Cells
- (2012) Anneleen Bosma et al. IMMUNITY
- B cell exchange across the blood-brain barrier in multiple sclerosis
- (2012) H.-Christian von Büdingen et al. JOURNAL OF CLINICAL INVESTIGATION
- B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6–producing B cells
- (2012) Tom A. Barr et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2012) Robert P. Lisak et al. JOURNAL OF NEUROIMMUNOLOGY
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- (2012) Hiroshi Kuroda et al. JOURNAL OF NEUROIMMUNOLOGY
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- (2012) Nasrin Asgari et al. JOURNAL OF NEUROIMMUNOLOGY
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- (2012) Mahdia Benkhoucha et al. Journal of Neuroinflammation
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- (2012) Michael J Koziolek et al. Journal of Neuroinflammation
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- (2012) Markus C Kowarik et al. Journal of Neuroinflammation
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- Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial
- (2012) Jeffrey A Cohen et al. LANCET
- Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial
- (2012) Alasdair J Coles et al. LANCET
- Clinical improvement in a patient with neuromyelitis optica following therapy with the anti-IL-6 receptor monoclonal antibody tocilizumab
- (2012) Manabu Araki et al. Modern Rheumatology
- Impaired regulatory function and enhanced intrathecal activation of B cells in neuromyelitis optica: distinct from multiple sclerosis
- (2012) Chao Quan et al. Multiple Sclerosis Journal
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- (2012) A Harrer et al. Multiple Sclerosis Journal
- Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions
- (2012) Ayumi Yoshizaki et al. NATURE
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- (2012) J. Kitley et al. NEUROLOGY
- Disease Amelioration With Tocilizumab in a Treatment-Resistant Patient With Neuromyelitis Optica
- (2012) Bernd C. Kieseier et al. JAMA Neurology
- Anti-Aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica
- (2011) Lukmanee Tradtrantip et al. ANNALS OF NEUROLOGY
- Human CD19+CD25high B regulatory cells suppress proliferation of CD4+ T cells and enhance Foxp3 and CTLA-4 expression in T-regulatory cells
- (2011) Aharon Kessel et al. AUTOIMMUNITY REVIEWS
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- (2011) Jürgen Scheller et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
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- Reduction in IL-10 producing B cells (Breg) in multiple sclerosis is accompanied by a reduced naïve/memory Breg ratio during a relapse but not in remission
- (2011) Stephanie Knippenberg et al. JOURNAL OF NEUROIMMUNOLOGY
- Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders
- (2011) Simone Mader et al. Journal of Neuroinflammation
- Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial
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- Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis
- (2011) A. K. Probstel et al. NEUROLOGY
- Long-term follow-up of patients with neuromyelitis optica after repeated therapy with rituximab
- (2011) H. L. Pellkofer et al. NEUROLOGY
- Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica
- (2011) Norio Chihara et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IL-6 increases B-cell IgG production in a feed-forward proinflammatory mechanism to skew hematopoiesis and elevate myeloid production
- (2010) K. Maeda et al. BLOOD
- Enhanced IL-6 Production in Aquaporin-4 Antibody Positive Neuromyelitis Optica Patients
- (2010) Sema İİçöz et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Cutting Edge: Novel Function of B Cell-Activating Factor in the Induction of IL-10-Producing Regulatory B Cells
- (2010) M. Yang et al. JOURNAL OF IMMUNOLOGY
- A unique antibody gene signature is prevalent in the central nervous system of patients with multiple sclerosis
- (2010) A.J. Ligocki et al. JOURNAL OF NEUROIMMUNOLOGY
- Standardized method for the detection of antibodies to aquaporin-4 based on a highly sensitive immunofluorescence assay employing recombinant target antigen
- (2010) S. Jarius et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- AQP4 antibodies in neuromyelitis optica: diagnostic and pathogenetic relevance
- (2010) Sven Jarius et al. Nature Reviews Neurology
- Regulatory B cells in autoimmunity: developments and controversies
- (2010) Claudia Mauri et al. Nature Reviews Rheumatology
- The Chemokine CXCL13 Is a Prognostic Marker in Clinically Isolated Syndrome (CIS)
- (2010) Johannes Brettschneider et al. PLoS One
- Atacicept: targeting B cells in multiple sclerosis
- (2010) Hans-Peter Hartung et al. Therapeutic Advances in Neurological Disorders
- Neuromyelitis optica: Pathogenicity of patient immunoglobulin in vivo
- (2009) Monika Bradl et al. ANNALS OF NEUROLOGY
- Intrathecal pathogenic antiâaquaporin-4 antibodies in early neuromyelitis optica
- (2009) Jeffrey L. Bennett et al. ANNALS OF NEUROLOGY
- Immunoglobulins and complement in postmortem multiple sclerosis tissue
- (2009) Michael H. Barnett et al. ANNALS OF NEUROLOGY
- Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?
- (2009) Amit Bar-Or et al. ANNALS OF NEUROLOGY
- A High-Affinity Fully Human Anti-IL-6 mAb, 1339, for the Treatment of Multiple Myeloma
- (2009) M. Fulciniti et al. CLINICAL CANCER RESEARCH
- IL-10 Mediates Resistance to Adoptive Transfer Experimental Autoimmune Encephalomyelitis in MyD88 −/− Mice
- (2009) Shmuel J. Cohen et al. JOURNAL OF IMMUNOLOGY
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- (2009) Elizabeth M. Cameron et al. JOURNAL OF NEUROIMMUNOLOGY
- Identification of BLyS (B Lymphocyte Stimulator), a Non-Myelin-Associated Protein, as a Functional Ligand for Nogo-66 Receptor
- (2009) L. Zhang et al. JOURNAL OF NEUROSCIENCE
- Homogeneity of active demyelinating lesions in established multiple sclerosis
- (2008) Esther C. W. Breij et al. ANNALS OF NEUROLOGY
- B-cell tolerance checkpoints in health and autoimmunity
- (2008) Eric Meffre et al. CURRENT OPINION IN IMMUNOLOGY
- CSF IgG heavy-chain bias in patients at the time of a clinically isolated syndrome
- (2008) Jeffrey L. Bennett et al. JOURNAL OF NEUROIMMUNOLOGY
- Polyspecific, antiviral immune response distinguishes multiple sclerosis and neuromyelitis optica
- (2008) S Jarius et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Natalizumab disproportionately increases circulating pre-B and B cells in multiple sclerosis
- (2008) M. Krumbholz et al. NEUROLOGY
- Multiple roles of chemokine CXCL12 in the central nervous system: A migration from immunology to neurobiology
- (2007) M LI et al. PROGRESS IN NEUROBIOLOGY
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