Small-molecule inhibitors of NMO-IgG binding to aquaporin-4 reduce astrocyte cytotoxicity in neuromyelitis optica

Novel Immunomodulatory Properties of Berbamine through Selective Down-Regulation of STAT4 and Action of IFN-  in Experimental Autoimmune Encephalomyelitis

(2014) Y. Ren et al.   JOURNAL OF IMMUNOLOGY

Aquaporin-4: orthogonal array assembly, CNS functions and role in neuromyelitis optica

(2011) Alan S Verkman et al.   ACTA PHARMACOLOGICA SINICA

Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms

(2011) Hua Zhang et al.   ANNALS OF NEUROLOGY

Anti-Aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica

(2011) Lukmanee Tradtrantip et al.   ANNALS OF NEUROLOGY

Model of Aquaporin-4 Supramolecular Assembly in Orthogonal Arrays Based on Heterotetrameric Association of M1-M23 Isoforms

(2011) Byung-Ju Jin et al.   BIOPHYSICAL JOURNAL

Proinflammatory role of aquaporin-4 in autoimmune neuroinflammation

(2011) Lihua Li et al.   FASEB JOURNAL

Binding Affinity and Specificity of Neuromyelitis Optica Autoantibodies to Aquaporin-4 M1/M23 Isoforms and Orthogonal Arrays

(2011) Jonathan M. Crane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oligodendrocytes are damaged by neuromyelitis optica immunoglobulin G via astrocyte injury

(2010) Romain Marignier et al.   BRAIN

Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice

(2010) Samira Saadoun et al.   BRAIN

Aquaporin-4 (AQP4) Associations and Array Dynamics Probed by Photobleaching and Single-molecule Analysis of Green Fluorescent Protein-AQP4 Chimeras

(2010) Masato Tajima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuromyelitis optica: a demyelinating disease characterized by acute destruction and regeneration of perivascular astrocytes

(2010) John DE Parratt et al.   Multiple Sclerosis Journal

AQP4 antibodies in neuromyelitis optica: diagnostic and pathogenetic relevance

(2010) Sven Jarius et al.   Nature Reviews Neurology

Patterns of Antibody Binding to Aquaporin-4 Isoforms in Neuromyelitis Optica

(2010) Simone Mader et al.   PLoS One

Berbamine exhibits potent antitumor effects on imatinib-resistant CML cells in vitro and in vivo

(2009) Yan-lin Wei et al.   ACTA PHARMACOLOGICA SINICA

Neuromyelitis optica: Pathogenicity of patient immunoglobulin in vivo

(2009) Monika Bradl et al.   ANNALS OF NEUROLOGY

Intrathecal pathogenic anti–aquaporin-4 antibodies in early neuromyelitis optica

(2009) Jeffrey L. Bennett et al.   ANNALS OF NEUROLOGY

Neuromyelitis optica: Passive transfer to rats by human immunoglobulin

(2009) Makoto Kinoshita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pharmacokinetic properties and bioequivalence of two formulations of arbidol: An open-label, single-dose, randomized-sequence, two-period crossover study in healthy chinese male volunteers

(2009) Ming-Yan Liu et al.   CLINICAL THERAPEUTICS

Live Cell Analysis of Aquaporin-4 M1/M23 Interactions and Regulated Orthogonal Array Assembly in Glial Cells

(2009) Jonathan M. Crane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Determinants of aquaporin-4 assembly in orthogonal arrays revealed by live-cell single-molecule fluorescence imaging

(2009) J. M. Crane et al.   JOURNAL OF CELL SCIENCE

Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance

(2009) J. D. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides

(2008) Baoxue Yang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Arbidol: A Broad-Spectrum Antiviral Compound that Blocks Viral Fusion

(2008) Y. Boriskin et al.   CURRENT MEDICINAL CHEMISTRY

Neuromyelitis optica: Diagnosis, pathogenesis, and treatment

(2008) Bruce Cree   Current Neurology and Neuroscience Reports

Mechanisms of Disease: aquaporin-4 antibodies in neuromyelitis optica

(2008) Sven Jarius et al.   Nature clinical practice. Neurology