A combination hydrogel microparticle-based vaccine prevents type 1 diabetes in non-obese diabetic mice

IL-4/CCL22/CCR4 Axis Controls Regulatory T-Cell Migration That Suppresses Inflammatory Bone Loss in Murine Experimental Periodontitis

(2015) Ana Claudia Araujo-Pires et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Integrin-directed modulation of macrophage responses to biomaterials

(2014) Toral D. Zaveri et al.   BIOMATERIALS

Materials that harness and modulate the immune system

(2014) Jamal S. Lewis et al.   MRS BULLETIN

Gradated assembly of multiple proteins into supramolecular nanomaterials

(2014) Gregory A. Hudalla et al.   NATURE MATERIALS

The effect of cyclic mechanical strain on activation of dendritic cells cultured on adhesive substrates

(2013) Jamal S. Lewis et al.   BIOMATERIALS

Modulation of leukocyte infiltration and phenotype in microporous tissue engineering scaffolds via vector induced IL-10 expression

(2013) R. Michael Gower et al.   BIOMATERIALS

Engineering synthetic vaccines using cues from natural immunity

(2013) Darrell J. Irvine et al.   NATURE MATERIALS

Preparation and Efficacy of Newcastle Disease Virus DNA Vaccine Encapsulated in PLGA Nanoparticles

(2013) Kai Zhao et al.   PLoS One

Prevention of inflammation-mediated bone loss in murine and canine periodontal disease via recruitment of regulatory lymphocytes

(2013) A. J. Glowacki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Self-Adjuvanting Supramolecular Vaccine Carrying a Folded Protein Antigen

(2013) Gregory A. Hudalla et al.   Advanced Healthcare Materials

Combinatorial delivery of immunosuppressive factors to dendritic cells using dual-sized microspheres

(2013) Jamal S. Lewis et al.   Journal of Materials Chemistry B

TLR9 agonist CpG enhances protective nasal HSP60 peptide vaccine efficacy in experimental autoimmune arthritis

(2012) Evelien Zonneveld-Huijssoon et al.   ANNALS OF THE RHEUMATIC DISEASES

Microparticle surface modifications targeting dendritic cells for non-activating applications

(2012) Jamal S. Lewis et al.   BIOMATERIALS

Type 1 Diabetes: Current Concepts in Epidemiology, Pathophysiology, Clinical Care, and Research

(2012) Mary Joyce Gan et al.   Current Problems in Pediatric and Adolescent Health Care

Vaccines: From Empirical Development to Rational Design

(2012) Christine Rueckert et al.   PLoS Pathogens

Diabetes Complications: The MicroRNA Perspective

(2011) P. Kantharidis et al.   DIABETES

Controlled release of insulin from self-assembling nanofiber hydrogel, PuraMatrix™: Application for the subcutaneous injection in rats

(2011) Asako Nishimura et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

CpG DNA as a vaccine adjuvant

(2011) Christian Bode et al.   Expert Review of Vaccines

Multifunctional dendritic cell-targeting polymeric microparticles

(2011) Benjamin G. Keselowsky et al.   Human vaccines & immunotherapeutics

Cytoplasmic DNA innate immune pathways

(2011) Glen N. Barber   IMMUNOLOGICAL REVIEWS

An injectable synthetic immune-priming center mediates efficient T-cell class switching and T-helper 1 response against B cell lymphoma

(2011) Ankur Singh et al.   JOURNAL OF CONTROLLED RELEASE

Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial

(2011) Diane K Wherrett et al.   LANCET

Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies

(2011) Tom L. Van Belle et al.   PHYSIOLOGICAL REVIEWS

Intravital microscopy imaging of macrophage localization to immunogenic particles and co-localized tissue oxygen saturation

(2010) Se-woon Choe et al.   Acta Biomaterialia

Adhesive substrates modulate the activation and stimulatory capacity of non-obese diabetic mouse-derived dendritic cells

(2010) Abhinav P. Acharya et al.   Acta Biomaterialia

The modulation of dendritic cell integrin binding and activation by RGD-peptide density gradient substrates

(2010) Abhinav P. Acharya et al.   BIOMATERIALS

Contributions of surface topography and cytotoxicity to the macrophage response to zinc oxide nanorods

(2010) Toral D. Zaveri et al.   BIOMATERIALS

GM-CSF induces bone marrow precursors of NOD mice to skew into tolerogenic dendritic cells that protect against diabetes

(2010) Simon Gaudreau et al.   CELLULAR IMMUNOLOGY

Extended evaluation of the safety and efficacy of GAD treatment of children and adolescents with recent-onset type 1 diabetes: a randomised controlled trial

(2010) J. Ludvigsson et al.   DIABETOLOGIA

Reversal of Autoimmunity by Boosting Memory-like Autoregulatory T Cells

(2010) Sue Tsai et al.   IMMUNITY

Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists

(2009) Jörg Vollmer et al.   ADVANCED DRUG DELIVERY REVIEWS

A high-throughput microparticle microarray platform for dendritic cell-targeting vaccines

(2009) Abhinav P. Acharya et al.   BIOMATERIALS

In-situ crosslinking hydrogels for combinatorial delivery of chemokines and siRNA–DNA carrying microparticles to dendritic cells

(2009) Ankur Singh et al.   BIOMATERIALS

Modulation of dendritic cells using granulocyte-macrophage colony-stimulating factor (GM-CSF) delays type 1 diabetes by enhancing CD4+CD25+ regulatory T cell function

(2009) Donald Cheatem et al.   CLINICAL IMMUNOLOGY

Mechanism of action of clinically approved adjuvants

(2009) Bart N Lambrecht et al.   CURRENT OPINION IN IMMUNOLOGY

Effect of immunological adjuvants: GM-CSF (granulocyte-monocyte colony stimulating factor) and IL-23 (interleukin-23) on immune responses generated against hepatitis C virus core DNA vaccine

(2009) Christine Hartoonian et al.   CYTOKINE

Current advances in research and clinical applications of PLGA-based nanotechnology

(2009) Jian-Ming Lü et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy

(2009) Tihamer Orban et al.   JOURNAL OF AUTOIMMUNITY

Infection-mimicking materials to program dendritic cells in situ

(2009) Omar A. Ali et al.   NATURE MATERIALS

Controlled release of functional proteins through designer self-assembling peptide nanofiber hydrogel scaffold

(2009) S. Koutsopoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Production of self-assembling biomaterials for tissue engineering

(2009) Stuart Kyle et al.   TRENDS IN BIOTECHNOLOGY

Adhesive substrate-modulation of adaptive immune responses

(2008) Abhinav P. Acharya et al.   BIOMATERIALS

A Microsphere-Based Vaccine Prevents and Reverses New-Onset Autoimmune Diabetes

(2008) B. Phillips et al.   DIABETES

Excessive CpG 1668 stimulation triggers IL-10 production by cDC that inhibits IFN-α responses by pDC

(2008) Zoe Waibler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

PLGA microspheres for the delivery of a novel subunit TB vaccine

(2008) Daniel J. Kirby et al.   JOURNAL OF DRUG TARGETING

Antigen-Specific Tolerogenic and Immunomodulatory Strategies for the Treatment of Autoimmune Arthritis

(2008) Shailesh R. Satpute et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Co-delivery of cancer-associated antigen and Toll-like receptor 4 ligand in PLGA nanoparticles induces potent CD8+ T cell-mediated anti-tumor immunity

(2008) Samar Hamdy et al.   VACCINE

Inverse opal hydrogel-collagen composite scaffolds as a supportive microenvironment for immune cell migration

(2007) Agnieszka N. Stachowiak et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A