Cells alter their tRNA abundance to selectively regulate protein synthesis during stress conditions

mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases

(2018) Michael W. Webster et al.   MOLECULAR CELL

Codon-specific translation reprogramming promotes resistance to targeted therapy

(2018) Francesca Rapino et al.   NATURE

ALKBH1-Mediated tRNA Demethylation Regulates Translation

(2016) Fange Liu et al.   CELL

Modulated Expression of Specific tRNAs Drives Gene Expression and Cancer Progression

(2016) Hani Goodarzi et al.   CELL

Codon-Driven Translational Efficiency Is Stable across Diverse Mammalian Cell States

(2016) Konrad L. M. Rudolph et al.   PLoS Genetics

Optimization of Codon Translation Rates via tRNA Modifications Maintains Proteome Integrity

(2015) Danny D. Nedialkova et al.   CELL

Codon Optimality Is a Major Determinant of mRNA Stability

(2015) Vladimir Presnyak et al.   CELL

Pausing on Polyribosomes: Make Way for Elongation in Translational Control

(2015) Joel D. Richter et al.   CELL

The Levels of a Universally Conserved tRNA Modification Regulate Cell Growth

(2015) Diego Rojas-Benitez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficient and quantitative high-throughput tRNA sequencing

(2015) Guanqun Zheng et al.   NATURE METHODS

Trade-offs between tRNA abundance and mRNA secondary structure support smoothing of translation elongation rate

(2015) Thomas E. Gorochowski et al.   NUCLEIC ACIDS RESEARCH

Rationally designed, heterologousS. cerevisiaetranscripts expose novel expression determinants

(2015) Tuval Ben-Yehezkel et al.   RNA Biology

Codon-biased translation can be regulated by wobble-base tRNA modification systems during cellular stress responses

(2015) Lauren Endres et al.   RNA Biology

Integrated tRNA, transcript, and protein profiles in response to steroid hormone signaling

(2015) Kevin Van Bortle et al.   RNA

Trm9-Catalyzed tRNA Modifications Regulate Global Protein Expression by Codon-Biased Translation

(2015) Wenjun Deng et al.   PLoS Genetics

A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation

(2014) Hila Gingold et al.   CELL

Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders

(2014) S. Blanco et al.   EMBO JOURNAL

Systematic identification of tRNAome and its dynamics inLactococcus lactis

(2014) Pranav Puri et al.   MOLECULAR MICROBIOLOGY

Diverse cell stresses induce unique patterns of tRNA up- and down-regulation: tRNA-seq for quantifying changes in tRNA copy number

(2014) Yan Ling Joy Pang et al.   NUCLEIC ACIDS RESEARCH

The effect of tRNA levels on decoding times of mRNA codons

(2014) Alexandra Dana et al.   NUCLEIC ACIDS RESEARCH

Mean of the Typical Decoding Rates: A New Translation Efficiency Index Based on the Analysis of Ribosome Profiling Data

(2014) Alexandra Dana et al.   G3-Genes Genomes Genetics

A Comprehensive tRNA Deletion Library Unravels the Genetic Architecture of the tRNA Pool

(2014) Zohar Bloom-Ackermann et al.   PLoS Genetics

Rate-Limiting Steps in Yeast Protein Translation

(2013) Premal Shah et al.   CELL

A novel single-cell screening platform reveals proteome plasticity during yeast stress responses

(2013) Michal Breker et al.   JOURNAL OF CELL BIOLOGY

Translational sensitivity of the Escherichia coli genome to fluctuating tRNA availability

(2013) Sibylle E. Wohlgemuth et al.   NUCLEIC ACIDS RESEARCH

Loss of a Conserved tRNA Anticodon Modification Perturbs Cellular Signaling

(2013) Boris Zinshteyn et al.   PLoS Genetics

Translational reprogramming in cellular stress response

(2013) Botao Liu et al.   Wiley Interdisciplinary Reviews-RNA

tRNA genes rapidly change in evolution to meet novel translational demands

(2013) Avihu H Yona et al.   eLife

Genes adopt non-optimal codon usage to generate cell cycle-dependent oscillations in protein levels

(2012) Milana Frenkel-Morgenstern et al.   Molecular Systems Biology

Evolutionary conservation of codon optimality reveals hidden signatures of cotranslational folding

(2012) Sebastian Pechmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynamic changes in translational efficiency are deduced from codon usage of the transcriptome

(2012) Hila Gingold et al.   NUCLEIC ACIDS RESEARCH

Genome-wide ribosome profiling reveals complex translational regulation in response to oxidative stress

(2012) M. V. Gerashchenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maf1-mediated repression of RNA polymerase III transcription inhibits tRNA degradation via RTD pathway

(2012) T. W. Turowski et al.   RNA

Speeding with control: codon usage, tRNAs, and ribosomes

(2012) Eva Maria Novoa et al.   TRENDS IN GENETICS

P-Bodies and Stress Granules: Possible Roles in the Control of Translation and mRNA Degradation

(2012) C. J. Decker et al.   Cold Spring Harbor Perspectives in Biology

Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins

(2012) Clement T.Y. Chan et al.   Nature Communications

Multiobjective evolutionary algorithms to identify highly autocorrelated areas: the case of spatial distribution in financially compromised farms

(2011) Carlos R. García-Alonso et al.   ANNALS OF OPERATIONS RESEARCH

Visual gene developer: a fully programmable bioinformatics software for synthetic gene optimization

(2011) Sang-Kyu Jung et al.   BMC BIOINFORMATICS

Determinants of translation efficiency and accuracy

(2011) H. Gingold et al.   Molecular Systems Biology

Saccharomyces Genome Database: the genomics resource of budding yeast

(2011) J. M. Cherry et al.   NUCLEIC ACIDS RESEARCH

An Evolutionarily Conserved Mechanism for Controlling the Efficiency of Protein Translation

(2010) Tamir Tuller et al.   CELL

Translational Regulation of Gene Expression during Conditions of Cell Stress

(2010) Keith A. Spriggs et al.   MOLECULAR CELL

Validation of reference genes for quantitative expression analysis by real-time RT-PCR in Saccharomyces cerevisiae

(2009) Marie-Ange Teste et al.   BMC MOLECULAR BIOLOGY

Eukaryotic initiator tRNA: Finely tuned and ready for action

(2009) Sarah E. Kolitz et al.   FEBS LETTERS

The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress inSaccharomyces cerevisiae

(2009) Debrah M. Thompson et al.   JOURNAL OF CELL BIOLOGY

Coding-Sequence Determinants of Gene Expression in Escherichia coli

(2009) G. Kudla et al.   SCIENCE

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

Reprogramming mRNA translation during stress

(2008) Satoshi Yamasaki et al.   CURRENT OPINION IN CELL BIOLOGY

Single-RNA counting reveals alternative modes of gene expression in yeast

(2008) Daniel Zenklusen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Vienna RNA Websuite

(2008) A. R. Gruber et al.   NUCLEIC ACIDS RESEARCH