Translational reprogramming in cellular stress response

Sulfur Amino Acids Regulate Translational Capacity and Metabolic Homeostasis through Modulation of tRNA Thiolation

(2013) Sunil Laxman et al.   CELL

The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation

(2013) Gabriel Leprivier et al.   CELL

Rate-Limiting Steps in Yeast Protein Translation

(2013) Premal Shah et al.   CELL

Roles for transcript leaders in translation and mRNA decay revealed by transcript leader sequencing

(2013) J. A. Arribere et al.   GENOME RESEARCH

Coordinate Transcriptional and Translational Repression of p53 by TGF-β1 Impairs the Stress Response

(2013) Fernando J. López-Díaz et al.   MOLECULAR CELL

Reinitiation and Other Unconventional Posttermination Events during Eukaryotic Translation

(2013) Maxim A. Skabkin et al.   MOLECULAR CELL

Cotranslational Response to Proteotoxic Stress by Elongation Pausing of Ribosomes

(2013) Botao Liu et al.   MOLECULAR CELL

Widespread Regulation of Translation by Elongation Pausing in Heat Shock

(2013) Reut Shalgi et al.   MOLECULAR CELL

eIF5A Promotes Translation of Polyproline Motifs

(2013) Erik Gutierrez et al.   MOLECULAR CELL

An in vivo control map for the eukaryotic mRNA translation machinery

(2013) H. Firczuk et al.   Molecular Systems Biology

Extensive transcriptional heterogeneity revealed by isoform profiling

(2013) Vicent Pelechano et al.   NATURE

TSC on the peroxisome controls mTORC1

(2013) Don Benjamin et al.   NATURE CELL BIOLOGY

Genome-wide profiling of human cap-independent translation-enhancing elements

(2013) Brian P Wellensiek et al.   NATURE METHODS

Amino acid signalling upstream of mTOR

(2013) Jenna L. Jewell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State

(2013) S. Santagata et al.   SCIENCE

A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1

(2013) L. Bar-Peled et al.   SCIENCE

A Genome-Scale Integration and Analysis of Lactococcus lactis Translation Data

(2013) Julien Racle et al.   PLoS Computational Biology

Reversible and Rapid Transfer-RNA Deactivation as a Mechanism of Translational Repression in Stress

(2013) Andreas Czech et al.   PLoS Genetics

Ribosome profiling: a Hi-Def monitor for protein synthesis at the genome-wide scale

(2013) Audrey M. Michel et al.   Wiley Interdisciplinary Reviews-RNA

Translation regulation gets its ‘omics’ moment

(2013) Scott Kuersten et al.   Wiley Interdisciplinary Reviews-RNA

Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1

(2012) Liron Bar-Peled et al.   CELL

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

Genome-wide Identification and Quantitative Analysis of Cleaved tRNA Fragments Induced by Cellular Stress

(2012) Mridusmita Saikia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autism-related deficits via dysregulated eIF4E-dependent translational control

(2012) Christos G. Gkogkas et al.   NATURE

A tumour suppressor network relying on the polyamine–hypusine axis

(2012) Claudio Scuoppo et al.   NATURE

A unifying model for mTORC1-mediated regulation of mRNA translation

(2012) Carson C. Thoreen et al.   NATURE

The translational landscape of mTOR signalling steers cancer initiation and metastasis

(2012) Andrew C. Hsieh et al.   NATURE

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments

(2012) Nicholas T Ingolia et al.   Nature Protocols

Translational control in cellular and developmental processes

(2012) Jian Kong et al.   NATURE REVIEWS GENETICS

Specialized ribosomes: a new frontier in gene regulation and organismal biology

(2012) Shifeng Xue et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A mechanistic overview of translation initiation in eukaryotes

(2012) Colin Echeverría Aitken et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution

(2012) S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct perturbation of the translatome by the antidiabetic drug metformin

(2012) O. Larsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide ribosome profiling reveals complex translational regulation in response to oxidative stress

(2012) M. V. Gerashchenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EF-P Is Essential for Rapid Synthesis of Proteins Containing Consecutive Proline Residues

(2012) L. K. Doerfel et al.   SCIENCE

Translation Elongation Factor EF-P Alleviates Ribosome Stalling at Polyproline Stretches

(2012) S. Ude et al.   SCIENCE

Decoding Human Cytomegalovirus

(2012) N. Stern-Ginossar et al.   SCIENCE

Coupled Activation and Degradation of eEF2K Regulates Protein Synthesis in Response to Genotoxic Stress

(2012) F. Kruiswijk et al.   Science Signaling

Speeding with control: codon usage, tRNAs, and ribosomes

(2012) Eva Maria Novoa et al.   TRENDS IN GENETICS

Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins

(2012) Clement T.Y. Chan et al.   Nature Communications

Cellular Dynamics of RNA Modification

(2011) Chengqi Yi et al.   ACCOUNTS OF CHEMICAL RESEARCH

Translational control of eIF5A in various diseases

(2011) Annette Kaiser   AMINO ACIDS

Introns within Ribosomal Protein Genes Regulate the Production and Function of Yeast Ribosomes

(2011) Julie Parenteau et al.   CELL

Ribosome-Mediated Specificity in Hox mRNA Translation and Vertebrate Tissue Patterning

(2011) Nadya Kondrashov et al.   CELL

Selective Translation of Leaderless mRNAs by Specialized Ribosomes Generated by MazF in Escherichia coli

(2011) Oliver Vesper et al.   CELL

Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes

(2011) Nicholas T. Ingolia et al.   CELL

CPEB2-eEF2 interaction impedes HIF-1α RNA translation

(2011) Po-Jen Chen et al.   EMBO JOURNAL

Angiogenin-Induced tRNA Fragments Inhibit Translation Initiation

(2011) Pavel Ivanov et al.   MOLECULAR CELL

Identification of an mRNP Complex Regulating Tumorigenesis at the Translational Elongation Step

(2011) George S. Hussey et al.   MOLECULAR CELL

High-Resolution View of the Yeast Meiotic Program Revealed by Ribosome Profiling

(2011) G. A. Brar et al.   SCIENCE

Translational Pausing Ensures Membrane Targeting and Cytoplasmic Splicing of XBP1u mRNA

(2011) K. Yanagitani et al.   SCIENCE

Functional specialization of ribosomes?

(2011) Wendy V. Gilbert   TRENDS IN BIOCHEMICAL SCIENCES

How the Sequence of a Gene Can Tune Its Translation

(2010) Kurt Fredrick et al.   CELL

Polypyrimidine tract binding protein regulates IRES-mediated translation of p53 isoforms

(2010) Richa Grover et al.   CELL CYCLE

PI3K-mTORC1 Attenuates Stress Response by Inhibiting Cap-independent Hsp70 Translation

(2010) Jun Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative Ways to Think about Cellular Internal Ribosome Entry

(2010) Wendy V. Gilbert   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA Functions in Stress Responses

(2010) Anthony K.L. Leung et al.   MOLECULAR CELL

The Heat Shock Response: Life on the Verge of Death

(2010) Klaus Richter et al.   MOLECULAR CELL

Translational Regulation of Gene Expression during Conditions of Cell Stress

(2010) Keith A. Spriggs et al.   MOLECULAR CELL

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Yeast targets for mRNA methylation

(2010) Zsuzsanna Bodi et al.   NUCLEIC ACIDS RESEARCH

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small Peptides Switch the Transcriptional Activity of Shavenbaby During Drosophila Embryogenesis

(2010) T. Kondo et al.   SCIENCE

mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs

(2010) R. J. O. Dowling et al.   SCIENCE

Topology and Regulation of the Human eIF4A/4G/4H Helicase Complex in Translation Initiation

(2009) Assen Marintchev et al.   CELL

Stressing Out over tRNA Cleavage

(2009) Debrah M. Thompson et al.   CELL

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

RPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESs

(2009) D. M. Landry et al.   GENES & DEVELOPMENT

Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes

(2009) I. R. Powley et al.   GENES & DEVELOPMENT

Angiogenin cleaves tRNA and promotes stress-induced translational repression

(2009) Satoshi Yamasaki et al.   JOURNAL OF CELL BIOLOGY

Regulation of Protein Synthesis by Ionizing Radiation

(2009) S. Braunstein et al.   MOLECULAR AND CELLULAR BIOLOGY

Hypusine-containing protein eIF5A promotes translation elongation

(2009) Preeti Saini et al.   NATURE

Innate immune and chemically triggered oxidative stress modifies translational fidelity

(2009) Nir Netzer et al.   NATURE

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins

(2009) Günter Kramer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans

(2009) S. E. Calvo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cold-inducible RNA binding protein (CIRP) expression is modulated by alternative mRNAs

(2009) M. B. Al-Fageeh et al.   RNA

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling

(2008) Andrei V. Budanov et al.   CELL

Hypoxic Reactive Oxygen Species Regulate the Integrated Stress Response and Cell Survival

(2008) Liping Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Next-generation DNA sequencing

(2008) Jay Shendure et al.   NATURE BIOTECHNOLOGY

Regulation of TORC1 by Rag GTPases in nutrient response

(2008) Eunjung Kim et al.   NATURE CELL BIOLOGY

Crystal structure of the yeast eIF4A-eIF4G complex: An RNA-helicase controlled by protein-protein interactions

(2008) P. Schutz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

tRNA cleavage is a conserved response to oxidative stress in eukaryotes

(2008) D. M. Thompson et al.   RNA

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE