IFN-γ Directly Controls IL-33 Protein Level through a STAT1- and LMP2-dependent Mechanism

Macrophages Produce TGF- -Induced ( -ig-h3) following Ingestion of Apoptotic Cells and Regulate MMP14 Levels and Collagen Turnover in Fibroblasts

(2014) N. Nacu et al.   JOURNAL OF IMMUNOLOGY

Interleukin-33 Potentiates Bleomycin-Induced Lung Injury

(2013) Irina G. Luzina et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Interleukin-33-Dependent Innate Lymphoid Cells Mediate Hepatic Fibrosis

(2013) Tamar Mchedlidze et al.   IMMUNITY

Long-term IL-33–producing epithelial progenitor cells in chronic obstructive lung disease

(2013) Derek E. Byers et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-33 Induces Nuocytes and Modulates Liver Injury in Viral Hepatitis

(2013) Y. Liang et al.   JOURNAL OF IMMUNOLOGY

Components of the interleukin-33/ST2 system are differentially expressed and regulated in human cardiac cells and in cells of the cardiac vasculature

(2013) Svitlana Demyanets et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Skin-specific expression of IL-33 activates group 2 innate lymphoid cells and elicits atopic dermatitis-like inflammation in mice

(2013) Yasutomo Imai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-33: a Janus cytokine: Table 1

(2012) F Y Liew   ANNALS OF THE RHEUMATIC DISEASES

Emerging roles of immunoproteasomes beyond MHC class I antigen processing

(2012) Frédéric Ebstein et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Up-regulation of IL-33 expression in various types of murine cells by IL-3 and IL-4

(2012) Wei-Hua Zhao et al.   CYTOKINE

IL-33 attenuates EAE by suppressing IL-17 and IFN-γ production and inducing alternatively activated macrophages

(2012) Hui-Rong Jiang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Evidence for a regulatory loop between IFN-γ and IL-33 in skin inflammation

(2012) Jenny Seltmann et al.   EXPERIMENTAL DERMATOLOGY

IL-33 attenuates development and perpetuation of chronic intestinal inflammation

(2012) Philipp Gro et al.   INFLAMMATORY BOWEL DISEASES

Constant and steady transgene expression of interferon-γ by optimization of plasmid construct for safe and effective interferon-γ gene therapy

(2012) Mitsuru Ando et al.   JOURNAL OF GENE MEDICINE

Transcriptional Regulation of Murine IL-33 by TLR and Non-TLR Agonists

(2012) S. K. Polumuri et al.   JOURNAL OF IMMUNOLOGY

Full-Length IL-33 Promotes Inflammation but not Th2 Response In Vivo in an ST2-Independent Fashion

(2012) I. G. Luzina et al.   JOURNAL OF IMMUNOLOGY

Regulation of IL-33 Expression by IFN-γ and Tumor Necrosis Factor-α in Normal Human Epidermal Keratinocytes

(2012) Jitlada Meephansan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G

(2012) E. Lefrancais et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serum IL-33 levels are raised in patients with systemic sclerosis: association with extent of skin sclerosis and severity of pulmonary fibrosis

(2011) Koichi Yanaba et al.   CLINICAL RHEUMATOLOGY

IL-33 induces skin inflammation with mast cell and neutrophil activation

(2011) Axel J. Hueber et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Effect of topical interferon-γ gene therapy using gemini nanoparticles on pathophysiological markers of cutaneous scleroderma in Tsk/+ mice

(2011) I Badea et al.   GENE THERAPY

Splice isoforms of human interleukin-4 are functionally active in mice in vivo

(2011) Irina G. Luzina et al.   IMMUNOLOGY

Endogenous IL-33 enhances Th2 cytokine production and T-cell responses during allergic airway inflammation

(2011) Jennifer Louten et al.   INTERNATIONAL IMMUNOLOGY

The Dual Function Cytokine IL-33 Interacts with the Transcription Factor NF- B To Dampen NF- B-Stimulated Gene Transcription

(2011) S. Ali et al.   JOURNAL OF IMMUNOLOGY

Alternatively spliced variants of interleukin-4 promote inflammation differentially

(2011) I. G. Luzina et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inflammatory Bowel Disease-Associated Interleukin-33 Is Preferentially Expressed in Ulceration-Associated Myofibroblasts

(2010) Jon Sponheim et al.   AMERICAN JOURNAL OF PATHOLOGY

The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes

(2010) Andrew M. Pickering et al.   BIOCHEMICAL JOURNAL

IL-33 family members and asthma – bridging innate and adaptive immune responses

(2010) Clare M. Lloyd   CURRENT OPINION IN IMMUNOLOGY

Immunoproteasomes are essential for survival and expansion of T cells in virus-infected mice

(2010) Jacqueline Moebius et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Evidence for a role of immunoproteasomes in regulating cardiac muscle mass in diabetic mice

(2010) Lingyun Zu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IL-33 Prolongs Murine Cardiac Allograft Survival Through Induction of TH2-Type Immune Deviation

(2010) Hui Yin et al.   TRANSPLANTATION

Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis

(2009) Gaby Palmer et al.   ARTHRITIS AND RHEUMATISM

Regulation of pulmonary inflammation and fibrosis through expression of integrins αVβ3 and αVβ5 on pulmonary T lymphocytes

(2009) Irina G. Luzina et al.   ARTHRITIS AND RHEUMATISM

The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-γ production

(2009) Elvire Bourgeois et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases

(2009) Alexander U. Lüthi et al.   IMMUNITY

Cross-regulation of Signaling Pathways by Interferon-γ: Implications for Immune Responses and Autoimmune Diseases

(2009) Xiaoyu Hu et al.   IMMUNITY

IL-33 is upregulated in colonocytes of ulcerative colitis

(2009) Jakob Benedict Seidelin et al.   IMMUNOLOGY LETTERS

Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease

(2009) J Chapuis et al.   MOLECULAR PSYCHIATRY

The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1

(2009) C. Cayrol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors

(2008) Deborah J. Kuhn et al.   BLOOD

Ischemic preconditioning-induced cardioprotection is lost in mice with immunoproteasome subunit low molecular mass polypeptide-2 deficiency

(2008) Zheqing P. Cai et al.   FASEB JOURNAL

IL-1, IL-18, and IL-33 families of cytokines

(2008) William P. Arend et al.   IMMUNOLOGICAL REVIEWS

IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK Cells

(2008) M. D. Smithgall et al.   INTERNATIONAL IMMUNOLOGY

IL-33 reduces the development of atherosclerosis

(2008) Ashley M. Miller et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-33 exacerbates antigen-induced arthritis by activating mast cells

(2008) D. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA