Stereoselective synthesis of 3-amino-2-oxindoles from isatin imines: new scaffolds for bioactivity evaluation
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Stereoselective synthesis of 3-amino-2-oxindoles from isatin imines: new scaffolds for bioactivity evaluation
Authors
Keywords
-
Journal
RSC Advances
Volume 5, Issue 65, Pages 52481-52496
Publisher
Royal Society of Chemistry (RSC)
Online
2015-05-26
DOI
10.1039/c5ra06969f
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Brønsted Acid-Catalyzed Enantioselective Synthesis of Isatin- DerivedN,S-Acetals
- (2015) Christian Beceño et al. ADVANCED SYNTHESIS & CATALYSIS
- Organocatalytic Asymmetric Addition of Naphthols and Electron-Rich Phenols to Isatin-Derived Ketimines: Highly Enantioselective Construction of Tetrasubstituted Stereocenters
- (2015) Marc Montesinos-Magraner et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- An Organocatalytic Mannich/Denitration Reaction for the Asymmetric Synthesis of 3-Ethylacetate-Substitued 3-Amino-2-Oxindoles: Formal Synthesis of AG-041R
- (2015) Kun Zhao et al. CHEMISTRY-A EUROPEAN JOURNAL
- Chiral Bifunctional Guanidine-Catalyzed Enantioselective Aza-Henry Reaction of Isatin-Derived Ketimines
- (2015) Bing Fang et al. JOURNAL OF ORGANIC CHEMISTRY
- Maleimide as an efficient nucleophilic partner in the aza-Morita–Baylis–Hillman reaction: synthesis of chiral 3-substituted-3-aminooxindoles
- (2015) Akshay Kumar et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- A highly diastereoselective Friedel–Crafts reaction of indoles with isatin-derived N-sulfinyl ketimines towards the efficient synthesis of chiral tetrasubstituted 3-indolyl-3-aminooxindoles
- (2015) Jian-Ping Chen et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Asymmetric Ugi 3CR on isatin-derived ketimine: synthesis of chiral 3,3-disubstituted 3-aminooxindole derivatives
- (2014) Giordano Lesma et al. Beilstein Journal of Organic Chemistry
- Highly enantioselective aza-Henry reaction with isatin N-Boc ketimines
- (2014) Melireth Holmquist et al. CHEMICAL COMMUNICATIONS
- Catalytic Asymmetric Construction of 3,3′-Spirooxindoles Fused with Seven-Membered Rings by Enantioselective Tandem Reactions
- (2014) Yang Wang et al. CHEMISTRY-A EUROPEAN JOURNAL
- Diastereo- and Enantioselective Construction of a Bispirooxindole Scaffold Containing a Tetrahydro-β-carboline Moiety through an Organocatalytic Asymmetric Cascade Reaction
- (2014) Wei Dai et al. CHEMISTRY-A EUROPEAN JOURNAL
- Highly Diastereoselective Reaction of α-Diazoesters with Aryl Alcohols and Isatin Imines: Rapid Access to Oxindole-Derived α-Alkoxy-β-amino Acid Derivatives with Two Adjacent Quaternary Carbon Centers
- (2014) Tamilselvan Rajasekaran et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Lewis Acid Promoted Diastereoselective Addition of TMSCN and TMSCF3 to Isatin-Derived N-Sulfinyl Ketimines: Synthesis of Optically Active Tetrasubstituted 3-Aminooxindoles
- (2014) Diao Chen et al. JOURNAL OF ORGANIC CHEMISTRY
- (DHQ)2AQN-Catalyzed Asymmetric Substitution of Isatin-Derived Hydrazones with O-Boc-Protected Morita–Baylis–Hillman Adducts: A Strategy for Synthesizing Enantioenriched Azo Compounds Incorporating an Oxindole Scaffold
- (2014) Hai-Bin Yang et al. JOURNAL OF ORGANIC CHEMISTRY
- Organocatalyzed Enantioselective Mannich Reaction of Pyrazoleamides with Isatin-Derived Ketimines
- (2014) Tian-Ze Li et al. JOURNAL OF ORGANIC CHEMISTRY
- Enantioselective aza-Morita–Baylis–Hillman reaction between acrylates and N-Boc isatin ketimines: asymmetric construction of chiral 3-substituted-3-aminooxindoles
- (2014) Xuan Zhao et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Highly enantioselective synthesis of bisoxindoles with two vicinal quaternary stereocenters via Lewis base mediated addition of oxindoles to isatin-derived ketimines
- (2014) Zhongkai Tang et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Organocatalytic Enantioselective Addition of Thiols to Ketimines Derived from Isatins
- (2014) Shuichi Nakamura et al. ORGANIC LETTERS
- N-Heterocyclic Carbene-Catalyzed Chemoselective Cross-Aza-Benzoin Reaction of Enals with Isatin-Derived Ketimines: Access to Chiral Quaternary Aminooxindoles
- (2014) Jianfeng Xu et al. ORGANIC LETTERS
- Bis(imidazolidine)pyridine-NiCl2 Catalyst for Nitro-Mannich Reaction of Isatin-Derived N-Boc Ketimines: Asymmetric Synthesis of Chiral 3-Substituted 3-Amino-2-oxindoles
- (2014) Takayoshi Arai et al. ORGANIC LETTERS
- Bifunctional N-Heterocyclic Carbene-Catalyzed Highly Enantioselective Synthesis of Spirocyclic Oxindolo-β-lactams
- (2014) Han-Ming Zhang et al. ORGANIC LETTERS
- Cinchona-derived thiourea catalyzed hydrophosphonylation of ketimines—an enantioselective synthesis of α-amino phosphonates
- (2014) Akshay Kumar et al. TETRAHEDRON
- Organocatalytic direct asymmetric vinylogous Mannich reaction of γ-butenolides with isatin-derived ketimines
- (2014) Yunlong Guo et al. RSC Advances
- Organocatalytic enantioselective aza-Henry reaction of ketimines derived from isatins: access to optically active 3-amino-2-oxindoles
- (2014) Akshay Kumar et al. RSC Advances
- An Organocatalytic Addition of Nitromethane to Activated Ketimines
- (2014) Yu-Hui Wang et al. Asian Journal of Organic Chemistry
- Catalytic Asymmetric 1,3-Dipolar Cycloadditions of Alkynes with Isatin-Derived Azomethine Ylides: Enantioselective Synthesis of Spiro[indoline-3,2′-pyrrole] Derivatives
- (2013) Feng Shi et al. ADVANCED SYNTHESIS & CATALYSIS
- Recent Advances in Organocatalytic Asymmetric Morita–Baylis–Hillman/aza-Morita–Baylis–Hillman Reactions
- (2013) Yin Wei et al. CHEMICAL REVIEWS
- A Copper-Catalyzed One-Pot, Three-Component Diastereoselective Synthesis of 3-Spiroazetidinimine-2-oxindoles and Their Synthetic Transformation into Fluorescent Conjugated Indolones
- (2013) Somasundharam Periyaraja et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Enantioselective Squaramide-Catalysed Domino Mannich-Cyclization Reaction of Isatin Imines
- (2013) Xi-Bo Wang et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Catalytic Asymmetric Hydrophosphonylation of Ketimines
- (2013) Liang Yin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Asymmetric catalytic aza-Morita–Baylis–Hillman reaction for the synthesis of 3-substituted-3-aminooxindoles with chiral quaternary carbon centers
- (2013) Fang-Le Hu et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- First example of quinine-squaramide catalyzed enantioselective addition of diphenyl phosphite to ketimines derived from isatins
- (2013) Jimil George et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Rhodium-catalyzed three-component reaction of 3-diazooxindoles with indoles and isatin-derived ketimines: a facile and versatile approach to functionalized 3,3′,3′′-trisindoles
- (2013) Liang-Yong Mei et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Asymmetric One-Pot Sequential Mannich/Hydroamination Reaction by Organo- and Gold Catalysts: Synthesis of Spiro[pyrrolidin-3,2′-oxindole] Derivatives
- (2013) Xianjie Chen et al. ORGANIC LETTERS
- Catalytic enantioselective addition of alcohols to isatin-derived N-Boc ketimines
- (2013) Tian-Ze Li et al. TETRAHEDRON
- Organocatalytic asymmetric synthesis of 3-amino-2-oxindole derivatives bearing a tetra-substituted stereocenter
- (2013) Pankaj Chauhan et al. TETRAHEDRON-ASYMMETRY
- Morita–Baylis–Hillman adducts: Biological activities and potentialities to the discovery of new cheaper drugs
- (2012) Claudio G. Lima–Junior et al. BIOORGANIC & MEDICINAL CHEMISTRY
- The highly enantioselective addition of indoles and pyrroles to isatins-derived N-Boc ketimines catalyzed by chiral phosphoric acids
- (2012) Jingchao Feng et al. CHEMICAL COMMUNICATIONS
- Zn-mediated asymmetric allylation of N-tert-butanesulfinyl ketimines: an efficient and practical access to chiral quaternary 3-aminooxindoles
- (2012) Diao Chen et al. CHEMICAL COMMUNICATIONS
- Quinine-thiourea catalyzed enantioselective hydrophosphonylation of trifluoromethyl 2(1H)-quinazolinones
- (2012) Hexin Xie et al. CHEMICAL COMMUNICATIONS
- Organocatalytic asymmetric cyanation of isatin derived N-Boc ketoimines
- (2012) Yun-Lin Liu et al. CHEMICAL COMMUNICATIONS
- Isatins As Privileged Molecules in Design and Synthesis of Spiro-Fused Cyclic Frameworks
- (2012) Girija S. Singh et al. CHEMICAL REVIEWS
- N-Heterocyclic Carbene-Catalyzed Homoenolate Additions with N-Aryl Ketimines as Electrophiles: Efficient Synthesis of Spirocyclic γ-Lactam Oxindoles
- (2012) Bo Zhang et al. CHEMISTRY-A EUROPEAN JOURNAL
- Enantioselective Synthesis of AG-041R by using N-Heteroarenesulfonyl Cinchona Alkaloid Amides as Organocatalysts
- (2012) Noriyuki Hara et al. CHEMISTRY-A EUROPEAN JOURNAL
- Scaffold-Inspired Enantioselective Synthesis of Biologically Important Spiro[pyrrolidin-3,2′-oxindoles] with Structural Diversity through Catalytic Isatin-Derived 1,3-Dipolar Cycloadditions
- (2012) Feng Shi et al. CHEMISTRY-A EUROPEAN JOURNAL
- Enantioselective and Solvent-Controlled Diastereoselective Mannich Reaction of Isatin Imines with Hydroxyacetone: Synthesis of 3-Substituted 3-Aminooxindoles
- (2012) Qi-Xiang Guo et al. JOURNAL OF ORGANIC CHEMISTRY
- A Catalytic Asymmetric Isatin-Involved Povarov Reaction: Diastereo- and Enantioselective Construction of Spiro[indolin-3,2′-quinoline] Scaffold
- (2012) Feng Shi et al. ORGANIC LETTERS
- Highly Enantioselective Addition of Enals to Isatin-Derived Ketimines Catalyzed by N-Heterocyclic Carbenes: Synthesis of Spirocyclic γ-Lactams
- (2012) Hui Lv et al. ORGANIC LETTERS
- Synthesis of N-Alkoxycarbonyl Ketimines Derived from Isatins and Their Application in Enantioselective Synthesis of 3-Aminooxindoles
- (2012) Wenjin Yan et al. ORGANIC LETTERS
- Facile and highly diastereoselective synthesis of 3-aminooxindoles via AgOAc-catalyzed vinylogous Mannich reaction
- (2012) Yu-Hua Shi et al. TETRAHEDRON
- Recent advances in asymmetric organocatalytic conjugate addition of arenes and hetero-arenes
- (2012) Pankaj Chauhan et al. RSC Advances
- Recent developments in metal catalyzed asymmetric addition of phosphorus nucleophiles
- (2011) Depeng Zhao et al. CHEMICAL SOCIETY REVIEWS
- Transition-Metal-Mediated Routes to 3,3-Disubstituted Oxindoles through Anilide Cyclisation
- (2011) Johannes E. M. N. Klein et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Addition of TMSCN to chiral ketimines derived from isatin. Synthesis of an oxindole-based peptidomimetic and a bioactive spirohydantoin
- (2011) Alessandro Sacchetti et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Highly Functional Group Compatible Rh-Catalyzed Addition of Arylboroxines to ActivatedN-tert-Butanesulfinyl Ketimines
- (2011) Hyung Hoon Jung et al. ORGANIC LETTERS
- Recent progress in enantioselective synthesis of C3-functionalized oxindoles: rare earth metals take action
- (2011) Ke Shen et al. Chemical Science
- Multifunctional Chiral Phosphine Organocatalysts in Catalytic Asymmetric Morita−Baylis−Hillman and Related Reactions
- (2010) Yin Wei et al. ACCOUNTS OF CHEMICAL RESEARCH
- Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position
- (2010) Feng Zhou et al. ADVANCED SYNTHESIS & CATALYSIS
- Boronic Acids and Esters in the Petasis-Borono Mannich Multicomponent Reaction
- (2010) Nuno R. Candeias et al. CHEMICAL REVIEWS
- Recent Contributions from the Baylis−Hillman Reaction to Organic Chemistry
- (2010) Deevi Basavaiah et al. CHEMICAL REVIEWS
- Privileged chiral catalysts in asymmetric Morita-Baylis-Hillman/aza-Morita-Baylis-Hillman reaction
- (2010) Yin Wei et al. CHINESE SCIENCE BULLETIN
- Organocatalyzed Asymmetric Friedel-Crafts Reactions
- (2010) Vincent Terrasson et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- A facile method for the synthesis of oxindole based quaternary α-aminonitriles via the Strecker reaction
- (2010) Yun-Lin Liu et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Spiroindolones, a Potent Compound Class for the Treatment of Malaria
- (2010) M. Rottmann et al. SCIENCE
- Squaramide-Catalyzed Enantioselective Michael Addition of Diphenyl Phosphite to Nitroalkenes
- (2009) Ye Zhu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- aza-Baylis−Hillman Reaction
- (2009) Valérie Declerck et al. CHEMICAL REVIEWS
- Chiral Brønsted acid catalyzed Friedel–Crafts alkylation reactions
- (2009) Shu-Li You et al. CHEMICAL SOCIETY REVIEWS
- Organocatalytic Asymmetric Synthesis of Organophosphorus Compounds
- (2009) Åukasz Albrecht et al. CHEMISTRY-A EUROPEAN JOURNAL
- Grignard Addition to Imines Derived from Isatine: A Method for the Asymmetric Synthesis of Quaternary 3-Aminooxindoles
- (2009) Giordano Lesma et al. JOURNAL OF ORGANIC CHEMISTRY
- Catalytic Enantioselective Hydrophosphonylation of Ketimines Using Cinchona Alkaloids
- (2009) Shuichi Nakamura et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Non-peptide arginine-vasopressin antagonists: the vaptans
- (2008) Guy Decaux et al. LANCET
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now