The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex

Proline-rich antimicrobial peptides: potential therapeutics against antibiotic-resistant bacteria

(2014) Wenyi Li et al.   AMINO ACIDS

Insect-Derived Proline-Rich Antimicrobial Peptides Kill Bacteria by Inhibiting Bacterial Protein Translation at the 70 S Ribosome

(2014) Andor Krizsan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reconstitution of a Minimal Ribosome-Associated Ubiquitination Pathway with Purified Factors

(2014) Sichen Shao et al.   MOLECULAR CELL

Drug Sensing by the Ribosome Induces Translational Arrest via Active Site Perturbation

(2014) Stefan Arenz et al.   MOLECULAR CELL

A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome

(2014) Yury S Polikanov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Translational stalling at polyproline stretches is modulated by the sequence context upstream of the stall site

(2014) Agata L. Starosta et al.   NUCLEIC ACIDS RESEARCH

Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7

(2014) Michael Zahn et al.   PROTEIN AND PEPTIDE LETTERS

Blood-Brain Barrier Transport of Short Proline-Rich Antimicrobial Peptides

(2014) Sofie Stalmans et al.   PROTEIN AND PEPTIDE LETTERS

Cellular Uptake of Apidaecin 1b and Related Analogs in Gram-negative Bacteria Reveals Novel Antibacterial Mechanism for Proline-rich Antimicrobial Peptides

(2014) Nicole Berthold et al.   PROTEIN AND PEPTIDE LETTERS

Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide

(2014) Stefan Arenz et al.   Nature Communications

Molecular Basis for the Ribosome Functioning as an L-Tryptophan Sensor

(2014) Lukas Bischoff et al.   Cell Reports

The enhanced membrane interaction and perturbation of a cell penetrating peptide in the presence of anionic lipids: Toward an understanding of its selectivity for cancer cells

(2013) Marie-Lise Jobin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Functional Characterization of SbmA, a Bacterial Inner Membrane Transporter Required for Importing the Antimicrobial Peptide Bac7(1-35)

(2013) G. Runti et al.   JOURNAL OF BACTERIOLOGY

Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK

(2013) Michael Zahn et al.   JOURNAL OF MOLECULAR BIOLOGY

Ribosome-targeting antibiotics and mechanisms of bacterial resistance

(2013) Daniel N. Wilson   NATURE REVIEWS MICROBIOLOGY

Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis

(2013) L. Jenner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Api88 Is a Novel Antibacterial Designer Peptide To Treat Systemic Infections with Multidrug-Resistant Gram-Negative Pathogens

(2012) Patricia Czihal et al.   ACS Chemical Biology

Intracellular Toxicity of Proline-Rich Antimicrobial Peptides Shuttled into Mammalian Cells by the Cell-Penetrating Peptide Penetratin

(2012) Anne Hansen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Rational Design of Oncocin Derivatives with Superior Protease Stabilities and Antibacterial Activities Based on the High-Resolution Structure of the Oncocin-DnaK Complex

(2011) Daniel Knappe et al.   CHEMBIOCHEM

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Interplay between the Ribosomal Tunnel, Nascent Chain, and Macrolides Influences Drug Inhibition

(2010) Agata L. Starosta et al.   CHEMISTRY & BIOLOGY

The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide

(2010) Nora Vázquez-Laslop et al.   EMBO JOURNAL

Oncocin (VDKPPYLPRPRPPRRIYNR-NH2): A Novel Antibacterial Peptide Optimized against Gram-Negative Human Pathogens

(2010) Daniel Knappe et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action

(2010) J. A. Dunkle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revisiting the structures of several antibiotics bound to the bacterial ribosome

(2010) D. Bulkley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The A–Z of bacterial translation inhibitors

(2009) Daniel N. Wilson   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY