The A–Z of bacterial translation inhibitors

Recent Advances in the Chemistry and Biology of Naturally Occurring Antibiotics

(2009) K. C. Nicolaou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Thiopeptide Biosynthesis Featuring Ribosomally Synthesized Precursor Peptides and Conserved Posttranslational Modifications

(2009) Rijing Liao et al.   CHEMISTRY & BIOLOGY

GTPase activation of elongation factor EF-Tu by the ribosome during decoding

(2009) Jan-Christian Schuette et al.   EMBO JOURNAL

U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:

(2009) Güliz Gürel et al.   JOURNAL OF MOLECULAR BIOLOGY

Inhibition of Bacterial Ribosome Assembly: a Suitable Drug Target?

(2009) B. A. Maguire   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

An Unexpected Type of Ribosomes Induced by Kasugamycin: A Look into Ancestral Times of Protein Synthesis?

(2009) Anna Chao Kaberdina et al.   MOLECULAR CELL

Programmed drug-dependent ribosome stalling

(2009) Haripriya Ramu et al.   MOLECULAR MICROBIOLOGY

Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics inMycobacterium smegmatisby perturbation of the drug binding pocket

(2009) Katherine S. Long et al.   MOLECULAR MICROBIOLOGY

Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin

(2009) Laura C. Wieland Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis

(2009) E. Villa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct functions of elongation factor G in ribosome recycling and translocation

(2009) A. Savelsbergh et al.   RNA

Accuracy modulating mutations of the ribosomal protein S4-S5 interface do not necessarily destabilize the rps4-rps5 protein-protein interaction

(2009) H. Vallabhaneni et al.   RNA

Erythromycin- and Chloramphenicol-Induced Ribosomal Assembly Defects Are Secondary Effects of Protein Synthesis Inhibition

(2008) T. Siibak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Activities of the Rx-01 Oxazolidinones against Hospital and Community Pathogens

(2008) L. Lawrence et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

R -01, a New Family of Oxazolidinones That Overcome Ribosome-Based Linezolid Resistance

(2008) E. Skripkin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Linezolid and Tiamulin Cross-Resistance in Staphylococcus aureus Mediated by Point Mutations in the Peptidyl Transferase Center

(2008) K. Miller et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mode of Action of Ranbezolid against Staphylococci and Structural Modeling Studies of Its Interaction with Ribosomes

(2008) V. Kalia et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mistranslation of Membrane Proteins and Two-Component System Activation Trigger Antibiotic-Mediated Cell Death

(2008) Michael A. Kohanski et al.   CELL

Macrolide myths

(2008) Alexander S Mankin   CURRENT OPINION IN MICROBIOLOGY

Molecular characterisation of linezolid resistance in two vancomycin-resistant (VanB) Enterococcus faecium isolates using Pyrosequencing™

(2008) B. Saager et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Multidrug resistant to extensively drug resistant tuberculosis: What is next?

(2008) Amita Jain et al.   JOURNAL OF BIOSCIENCES

A Click Chemistry Approach to Pleuromutilin Conjugates with Nucleosides or Acyclic Nucleoside Derivatives and Their Binding to the Bacterial Ribosome

(2008) Line Lolk et al.   JOURNAL OF MEDICINAL CHEMISTRY

Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit∥

(2008) Joseph A. Ippolito et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant

(2008) Gregor Blaha et al.   JOURNAL OF MOLECULAR BIOLOGY

Electrostatics in the Ribosomal Tunnel Modulate Chain Elongation Rates

(2008) Jianli Lu et al.   JOURNAL OF MOLECULAR BIOLOGY

New Features of the Ribosome and Ribosomal Inhibitors: Non-Enzymatic Recycling, Misreading and Back-Translocation

(2008) Witold Szaflarski et al.   JOURNAL OF MOLECULAR BIOLOGY

Time-Resolved Binding of Azithromycin to Escherichia coli Ribosomes

(2008) Alexandros D. Petropoulos et al.   JOURNAL OF MOLECULAR BIOLOGY

Translational Regulation via L11: Molecular Switches on the Ribosome Turned On and Off by Thiostrepton and Micrococcin

(2008) Joerg M. Harms et al.   MOLECULAR CELL

Mechanistic insight into the ribosome biogenesis functions of the ancient protein KsgA

(2008) Keith Connolly et al.   MOLECULAR MICROBIOLOGY

Quality control by the ribosome following peptide bond formation

(2008) Hani S. Zaher et al.   NATURE

A structural understanding of the dynamic ribosome machine

(2008) Thomas A. Steitz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation

(2008) Sean R Connell et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

rRNA mutants in the yeast peptidyltransferase center reveal allosteric information networks and mechanisms of drug resistance

(2008) R. Rakauskaite et al.   NUCLEIC ACIDS RESEARCH

The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning

(2008) D. N. Wilson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for cross-resistance to ribosomal PTC antibiotics

(2008) C. Davidovich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutation from guanine to adenine in 25S rRNA at the position equivalent to E. coli A2058 does not confer erythromycin sensitivity in Sacchromyces cerevisae

(2008) A. S. Bommakanti et al.   RNA

Structural basis for hygromycin B inhibition of protein biosynthesis

(2008) M. A. Borovinskaya et al.   RNA