Proline-rich antimicrobial peptides: potential therapeutics against antibiotic-resistant bacteria

Mechanism of Escherichia coli Resistance to Pyrrhocoricin

(2014) S. Narayanan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Strategies To Deliver Peptide Drugs to the Brain

(2014) Aikaterini Lalatsa et al.   MOLECULAR PHARMACEUTICS

Diagnostics: Detection drives defence

(2014) Rebecca Kanthor   NATURE

Microbiology: Resistance fighters

(2014) Bill Cannon   NATURE

Public health: The politics of antibiotics

(2014) Megan Cully   NATURE

Antibiotic resistance: An infectious arms race

(2014) Karyn Hede   NATURE

Drug discovery: Leaving no stone unturned

(2014) Katharine Gammon   NATURE

The use of versatile plant antimicrobial peptides in agribusiness and human health

(2014) Elizabete de Souza Cândido et al.   PEPTIDES

Cellular Internalization and Cytotoxicity of the Antimicrobial Proline-rich Peptide Bac7(1-35) in Monocytes/Macrophages, and its Activity Against Phagocytosed Salmonella typhimurium

(2014) Chiara Pelillo et al.   PROTEIN AND PEPTIDE LETTERS

The Designer Proline-rich Antibacterial Peptide A3-APO Prevents Bacillus anthracis Mortality by Deactivating Bacterial Toxins

(2014) Laszlo Otvos et al.   PROTEIN AND PEPTIDE LETTERS

Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7

(2014) Michael Zahn et al.   PROTEIN AND PEPTIDE LETTERS

Blood-Brain Barrier Transport of Short Proline-Rich Antimicrobial Peptides

(2014) Sofie Stalmans et al.   PROTEIN AND PEPTIDE LETTERS

Cellular Uptake of Apidaecin 1b and Related Analogs in Gram-negative Bacteria Reveals Novel Antibacterial Mechanism for Proline-rich Antimicrobial Peptides

(2014) Nicole Berthold et al.   PROTEIN AND PEPTIDE LETTERS

Circular Dichroism studies on the interactions of antimicrobial peptides with bacterial cells

(2014) Concetta Avitabile et al.   Scientific Reports

Dimeric unnatural polyproline-rich peptides with enhanced antibacterial activity

(2013) Victor Hernandez-Gordillo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Rapid systemic and local treatments with the antibacterial peptide dimer A3-APO and its monomeric metabolite eliminate bacteria and reduce inflammation in intradermal lesions infected with Propionibacterium acnes and meticillin-resistant Staphylococcus aureus

(2013) Eszter Ostorhazi et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Antibiotics in the clinical pipeline in 2013

(2013) Mark S Butler et al.   JOURNAL OF ANTIBIOTICS

Functional Characterization of SbmA, a Bacterial Inner Membrane Transporter Required for Importing the Antimicrobial Peptide Bac7(1-35)

(2013) G. Runti et al.   JOURNAL OF BACTERIOLOGY

Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK

(2013) Michael Zahn et al.   JOURNAL OF MOLECULAR BIOLOGY

Antiviral Mechanisms of Human Defensins

(2013) Sarah S. Wilson et al.   JOURNAL OF MOLECULAR BIOLOGY

Antimicrobial peptides stage a comeback

(2013) Jeffrey L Fox   NATURE BIOTECHNOLOGY

Immune modulation by multifaceted cationic host defense (antimicrobial) peptides

(2013) Ashley L Hilchie et al.   Nature Chemical Biology

Structure-Activity Relationships of the Antimicrobial Peptide Arasin 1 — And Mode of Action Studies of the N-Terminal, Proline-Rich Region

(2013) Victoria S. Paulsen et al.   PLoS One

Diverse and abundant antibiotic resistance genes in Chinese swine farms

(2013) Yong-Guan Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strand Length-Dependent Antimicrobial Activity and Membrane-Active Mechanism of Arginine- and Valine-Rich β-Hairpin-Like Antimicrobial Peptides

(2012) Na Dong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences

(2012) Nada Ilić et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Study for Monitoring Antimicrobial Resistance Trends (SMART) in the Asia-Pacific region, 2002–2010

(2012) Po-Ren Hsueh   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Modulating immunity as a therapy for bacterial infections

(2012) Robert E. W. Hancock et al.   NATURE REVIEWS MICROBIOLOGY

Proline-rich antimicrobial peptides: converging to a non-lytic mechanism of action

(2011) Marco Scocchi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Antimicrobial peptides with cell-penetrating peptide properties and vice versa

(2011) Katrin Splith et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Broad-spectrum antimicrobial efficacy of peptide A3-APO in mouse models of multidrug-resistant wound and lung infections cannot be explained by in vitro activity against the pathogens involved

(2011) Eszter Ostorhazi et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

iTRAQ-Coupled 2-D LC-MS/MS Analysis of Membrane Protein Profile in Escherichia coli Incubated with Apidaecin IB

(2011) Yusi Zhou et al.   PLoS One

The proline-rich peptide Bac7(1-35) reduces mortality from Salmonella typhimurium in a mouse model of infection

(2010) Monica Benincasa et al.   BMC MICROBIOLOGY

Ctenidins: antimicrobial glycine-rich peptides from the hemocytes of the spider Cupiennius salei

(2010) Tommy Baumann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Synergy among antibacterial peptides and between peptides and small-molecule antibiotics

(2010) Marco Cassone et al.   Expert Review of Anti-Infective Therapy

Bactenecin 7 peptide fragment as a tool for intracellular delivery of a phosphorescent oxygen sensor

(2010) Ruslan I. Dmitriev et al.   FEBS Journal

Proline-rich domain of penaeidin molecule exhibits autocrine feature by attracting penaeidin-positive granulocytes toward the wound-induced inflammatory site

(2010) Ching-Yu Li et al.   FISH & SHELLFISH IMMUNOLOGY

Antimicrobial and immunomodulatory activities of an ovine proline/arginine-rich cathelicidin

(2010) Pak-Lam Yu et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Characterization of an abaecin-like antimicrobial peptide identified from a Pteromalus puparum cDNA clone

(2010) Xiaojing Shen et al.   JOURNAL OF INVERTEBRATE PATHOLOGY

Stylicins, a new family of antimicrobial peptides from the Pacific blue shrimp Litopenaeus stylirostris

(2010) J.L. Rolland et al.   MOLECULAR IMMUNOLOGY

Antimicrobial Peptides: Primeval Molecules or Future Drugs?

(2010) Brian M. Peters et al.   PLoS Pathogens

The Antibacterial Effect of a Proline-Rich Antibacterial Peptide A3-APO

(2009) F. Rozgonyi et al.   CURRENT MEDICINAL CHEMISTRY

The designer proline-rich antibacterial peptide A3-APO is effective against systemic Escherichia coli infections in different mouse models

(2009) Dora Szabo et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Induced Resistance to the Designer Proline-rich Antimicrobial Peptide A3-APO does not Involve Changes in the Intracellular Target DnaK

(2009) Marco Cassone et al.   International Journal of Peptide Research and Therapeutics

Classification of antimicrobial peptide using diversity measure with quadratic discriminant analysis

(2009) Wei Chen et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Membrane interactions of antimicrobial peptides from Australian frogs

(2008) David I. Fernandez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Molecular Basis for Proline- and Arginine-Rich Peptide Inhibition of Proteasome

(2008) Asokan Anbanandam et al.   JOURNAL OF MOLECULAR BIOLOGY

Cell-penetrating peptides as delivery vehicles for biology and medicine

(2008) Kelly M. Stewart et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Arasin 1, a proline–arginine-rich antimicrobial peptide isolated from the spider crab, Hyas araneus

(2007) Klara Stensvåg et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY