Piezo channels: from structure to function

Mutations in PIEZO2 Cause Gordon Syndrome, Marden-Walker Syndrome, and Distal Arthrogryposis Type 5

(2014) Margaret J. McMillin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Merkel Cells Transduce and Encode Tactile Stimuli to Drive Aβ-Afferent Impulses

(2014) Ryo Ikeda et al.   CELL

Piezo1 Is as a Novel Trefoil Factor Family 1 Binding Protein that Promotes Gastric Cancer Cell Mobility In Vitro

(2014) Xiao-Ning Yang et al.   DIGESTIVE DISEASES AND SCIENCES

Functional Role for Piezo1 in Stretch-evoked Ca2+Influx and ATP Release in Urothelial Cell Cultures

(2014) Tatsuya Miyamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Piezo2 expression in corneal afferent neurons

(2014) Romke Bron et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors

(2014) Srdjan Maksimovic et al.   NATURE

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

Transmembrane channel-like (TMC) genes are required for auditory and vestibular mechanosensation

(2014) Yoshiyuki Kawashima et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch

(2014) Kate Poole et al.   Nature Communications

Human PIEZO1: Removing Inactivation

(2013) Chilman Bae et al.   BIOPHYSICAL JOURNAL

Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1

(2013) I. Andolfo et al.   BLOOD

Mechano-Gated Ion Channels in Sensory Systems

(2013) Patrick Delmas et al.   CELL

Piezo1-dependent stretch-activated channels are inhibited by Polycystin-2 in renal tubular epithelial cells

(2013) Rémi Peyronnet et al.   EMBO REPORTS

Piezo1 plays a role in erythrocyte volume homeostasis

(2013) A. Faucherre et al.   HAEMATOLOGICA

piezo2bRegulates Vertebrate Light Touch Response

(2013) Adèle Faucherre et al.   JOURNAL OF NEUROSCIENCE

Runx1 Controls Terminal Morphology and Mechanosensitivity of VGLUT3-expressing C-Mechanoreceptors

(2013) S. Lou et al.   JOURNAL OF NEUROSCIENCE

Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis

(2013) B. Coste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1

(2013) C. Bae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for Piezo2 in EPAC1-dependent mechanical allodynia

(2013) N Eijkelkamp et al.   Nature Communications

Mutations in the mechanotransduction protein PIEZO1 are associated with hereditary xerocytosis

(2012) R. Zarychanski et al.   BLOOD

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

(2012) George T. Eisenhoffer et al.   NATURE

The role of Drosophila Piezo in mechanical nociception

(2012) Sung Eun Kim et al.   NATURE

Loss of the Integrin-Activating Transmembrane Protein Fam38A (Piezo1) Promotes a Switch to a Reduced Integrin-Dependent Mode of Cell Migration

(2012) Brian J. McHugh et al.   PLoS One

Iodine-131 Dose Dependent Gene Expression in Thyroid Cancers and Corresponding Normal Tissues Following the Chernobyl Accident

(2012) Michael Abend et al.   PLoS One

Inflammatory Signals Enhance Piezo2-Mediated Mechanosensitive Currents

(2012) Adrienne E. Dubin et al.   Cell Reports

The Mechanosensitive Ion Channel Piezo1 Is Inhibited by the Peptide GsMTx4

(2011) Chilman Bae et al.   BIOCHEMISTRY

Stomatin-domain proteins

(2011) Liudmilla Lapatsina et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Molecular mechanisms of mechanotransduction in mammalian sensory neurons

(2011) Patrick Delmas et al.   NATURE REVIEWS NEUROSCIENCE

Stretch-activated channels in pulmonary arterial smooth muscle cells from normoxic and chronically hypoxic rats

(2010) Thomas Ducret et al.   CELL CALCIUM

Gene expression signature discriminates sporadic from post-radiotherapy-induced thyroid tumors

(2010) C. Ory et al.   ENDOCRINE-RELATED CANCER

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Hereditary stomatocytosis and cation leaky red cells — Recent developments

(2009) Lesley J. Bruce   BLOOD CELLS MOLECULES AND DISEASES

Integrin activation by Fam38A uses a novel mechanism of R-Ras targeting to the endoplasmic reticulum

(2009) B. J. McHugh et al.   JOURNAL OF CELL SCIENCE

p73 poses a barrier to malignant transformation by limiting anchorage-independent growth

(2008) Michaela Beitzinger et al.   EMBO JOURNAL

Neurosensory mechanotransduction

(2008) Martin Chalfie   NATURE REVIEWS MOLECULAR CELL BIOLOGY