IL-1β Signaling Promotes CNS-Intrinsic Immune Control of West Nile Virus Infection

MyD88 Plays a Critical T Cell-Intrinsic Role in Supporting CD8 T Cell Expansion during Acute Lymphocytic Choriomeningitis Virus Infection

(2014) A. H. Rahman et al.   JOURNAL OF IMMUNOLOGY

Infectious Clones of Novel Lineage 1 and Lineage 2 West Nile Virus Strains WNV-TX02 and WNV-Madagascar

(2012) M. S. Suthar et al.   JOURNAL OF VIROLOGY

NLRP3 Inflammasome: Key Mediator of Neuroinflammation in Murine Japanese Encephalitis

(2012) Deepak Kumar Kaushik et al.   PLoS One

Interferon-Induced Ifit2/ISG54 Protects Mice from Lethal VSV Neuropathogenesis

(2012) Volker Fensterl et al.   PLoS Pathogens

IL-1 acts on T cells to enhance the magnitude of in vivo immune responses

(2011) S.Z. Ben-Sasson et al.   CYTOKINE

Inhibitor of κB Kinase ϵ (IKKϵ), STAT1, and IFIT2 Proteins Define Novel Innate Immune Effector Pathway against West Nile Virus Infection

(2011) Olivia Perwitasari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The NLRP3 Inflammasome Detects Encephalomyocarditis Virus and Vesicular Stomatitis Virus Infection

(2011) J. V. Rajan et al.   JOURNAL OF VIROLOGY

Beta Interferon Controls West Nile Virus Infection and Pathogenesis in Mice

(2011) H. M. Lazear et al.   JOURNAL OF VIROLOGY

Relative distribution of West Nile virus RNA in blood compartments: implications for blood donor nucleic acid amplification technology screening

(2011) Lori Lai et al.   TRANSFUSION

Activation of the NLRP3 inflammasome by intracellular poly I:C

(2010) Jayant V. Rajan et al.   FEBS LETTERS

The Innate Immune Adaptor Molecule MyD88 Restricts West Nile Virus Replication and Spread in Neurons of the Central Nervous System

(2010) K. J. Szretter et al.   JOURNAL OF VIROLOGY

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

(2010) Stephane Daffis et al.   NATURE

Persistence of West Nile Virus in the Central Nervous System and Periphery of Mice

(2010) Kim K. Appler et al.   PLoS One

IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

(2010) Mehul S. Suthar et al.   PLoS Pathogens

Toll-like Receptor 7 Mitigates Lethal West Nile Encephalitis via Interleukin 23-Dependent Immune Cell Infiltration and Homing

(2009) Terrence Town et al.   IMMUNITY

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

(2009) Irving C. Allen et al.   IMMUNITY

The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1

(2009) Paul G. Thomas et al.   IMMUNITY

Inflammasome recognition of influenza virus is essential for adaptive immune responses

(2009) Takeshi Ichinohe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T-cell intrinsic expression of MyD88 is required for sustained expansion of the virus-specific CD8+ T-cell population in LCMV-infected mice

(2009) C. Bartholdy et al.   JOURNAL OF GENERAL VIROLOGY

The Adaptor Molecule MyD88 Directly Promotes CD8 T Cell Responses to Vaccinia Virus

(2009) Yuan Zhao et al.   JOURNAL OF IMMUNOLOGY

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production

(2009) Hendrik Poeck et al.   NATURE IMMUNOLOGY

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

(2009) Tilmann Bürckstümmer et al.   NATURE IMMUNOLOGY

Cytokine and nitric oxide production by mouse macrophages infected with brazilian flaviviruses

(2009) Veridiana Ester Dias Barros et al.   REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO

Molecular mechanisms involved in inflammasome activation

(2009) Clare Bryant et al.   TRENDS IN CELL BIOLOGY

A critical role for direct TLR2-MyD88 signaling in CD8 T-cell clonal expansion and memory formation following vaccinia viral infection

(2008) M. Quigley et al.   BLOOD

The inflammatory cytokine, interleukin-1 beta, mediates loss of astroglial glutamate transport and drives excitotoxic motor neuron injury in the spinal cord during acute viral encephalomyelitis

(2008) Natalie A. Prow et al.   JOURNAL OF NEUROCHEMISTRY

Japanese Encephalitis Virus infection induces IL-18 and IL-1β in microglia and astrocytes: Correlation with in vitro cytokine responsiveness of glial cells and subsequent neuronal death

(2008) Sulagna Das et al.   JOURNAL OF NEUROIMMUNOLOGY

Tumor Necrosis Factor Alpha Protects against Lethal West Nile Virus Infection by Promoting Trafficking of Mononuclear Leukocytes into the Central Nervous System

(2008) B. Shrestha et al.   JOURNAL OF VIROLOGY

West Nile Virus Attenuates Activation of Primary Human Macrophages

(2008) Kok-Fai Kong et al.   VIRAL IMMUNOLOGY