Stem cell therapy for multiple sclerosis: preclinical evidence beyond all doubt?

CD11c+CD11b+ Dendritic Cells Play an Important Role in Intravenous Tolerance and the Suppression of Experimental Autoimmune Encephalomyelitis

(2014) H. Li et al.   JOURNAL OF IMMUNOLOGY

Variable behavior and complications of autologous bone marrow mesenchymal stem cells transplanted in experimental autoimmune encephalomyelitis

(2011) Nikolaos Grigoriadis et al.   EXPERIMENTAL NEUROLOGY

Clinical and pathological effects of intrathecal injection of mesenchymal stem cell-derived neural progenitors in an experimental model of multiple sclerosis

(2011) Violaine K. Harris et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Labeling of Luciferase/eGFP-Expressing Bone Marrow-Derived Stromal Cells with Fluorescent Micron-Sized Iron Oxide Particles Improves Quantitative and Qualitative Multimodal Imaging of Cellular Grafts In Vivo

(2011) Nathalie De Vocht et al.   MOLECULAR IMAGING AND BIOLOGY

Current Disease-Modifying Treatment of Multiple Sclerosis

(2011) Joy Derwenskus   MOUNT SINAI JOURNAL OF MEDICINE

Immune Mechanisms Underlying the Beneficial Effects of Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis

(2011) David Gosselin et al.   Neurotherapeutics

The mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: an open-label pre-test: post-test study with blinded outcome assessments

(2011) Peter Connick et al.   Trials

Safety and Immunological Effects of Mesenchymal Stem Cell Transplantation in Patients With Multiple Sclerosis and Amyotrophic Lateral Sclerosis

(2010) Dimitrios Karussis et al.   ARCHIVES OF NEUROLOGY

Neuroinflammation and Demyelination in Multiple Sclerosis After Allogeneic Hematopoietic Stem Cell Transplantation

(2010) Jian-Qiang Lu et al.   ARCHIVES OF NEUROLOGY

Clinical Potential of Intravenous Neural Stem Cell Delivery for Treatment of Neuroinflammatory Disease in Mice?

(2010) Kristien P. Reekmans et al.   CELL TRANSPLANTATION

Comparative Study of Methods for Administering Neural Stem/Progenitor Cells to Treat Spinal Cord Injury in Mice

(2010) Yuichiro Takahashi et al.   CELL TRANSPLANTATION

Safety and Feasibility of Autologous Bone Marrow Cellular Therapy in Relapsing-Progressive Multiple Sclerosis

(2010) C M Rice et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Time-dependent fate of transplanted neural precursor cells in experimental autoimmune encephalomyelitis mice

(2010) Angeliki Giannakopoulou et al.   EXPERIMENTAL NEUROLOGY

Bone marrow mesenchymal stem cell transplantation in patients with multiple sclerosis: A pilot study

(2010) Bassem Yamout et al.   JOURNAL OF NEUROIMMUNOLOGY

CNS-targeted LIF Expression Improves Therapeutic Efficacy and Limits Autoimmune-mediated Demyelination in a Model of Multiple Sclerosis

(2010) Helena Slaets et al.   MOLECULAR THERAPY

High-dose immunoablation with autologous haematopoietic stem cell transplantation in aggressive multiple sclerosis: a single centre 10-year experience

(2010) Eva Krasulová et al.   Multiple Sclerosis Journal

Inflammatory changes induced by transplanted neural precursor cells in a multiple sclerosis model

(2010) Angeliki Giannakopoulou et al.   NEUROREPORT

Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6

(2009) Ryang Hwa Lee et al.   Cell Stem Cell

The level of B7 homologue 1 expression on brain DC is decisive for CD8 Treg cell recruitment into the CNS during EAE

(2009) Alla L. Zozulya et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis

(2009) Lianhua Bai et al.   GLIA

Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis

(2009) Jingxian Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Mesenchymal Stromal Cells Ameliorate Experimental Autoimmune Encephalomyelitis by Inhibiting CD4 Th17 T Cells in a CC Chemokine Ligand 2-Dependent Manner

(2009) Moutih Rafei et al.   JOURNAL OF IMMUNOLOGY

Intracerebroventricular Transplantation of Human Mesenchymal Stem Cells Induced to Secrete Neurotrophic Factors Attenuates Clinical Symptoms in a Mouse Model of Multiple Sclerosis

(2009) Yael Barhum et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Neuroprotective mesenchymal stem cells are endowed with a potent antioxidant effectin vivo

(2009) Cristina Lanza et al.   JOURNAL OF NEUROCHEMISTRY

Transplanted myogenic progenitor cells express neuronal markers in the CNS and ameliorate disease in Experimental Autoimmune Encephalomyelitis

(2009) Rina Aharoni et al.   JOURNAL OF NEUROIMMUNOLOGY

Bone marrow stromal cell therapy reduces proNGF and p75 expression in mice with experimental autoimmune encephalomyelitis

(2009) Jing Zhang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: a phase I/II study

(2009) Richard K Burt et al.   LANCET NEUROLOGY

Allogeneic Mesenchymal Stem Cells for Treatment of Experimental Autoimmune Encephalomyelitis

(2009) Moutih Rafei et al.   MOLECULAR THERAPY

Autologous haematopoietic stem-cell transplantation in multiple sclerosis: benefits and risks

(2009) E. Capello et al.   NEUROLOGICAL SCIENCES

Immune Regulatory Neural Stem/Precursor Cells Protect from Central Nervous System Autoimmunity by Restraining Dendritic Cell Function

(2009) Stefano Pluchino et al.   PLoS One

Adipose-Derived Mesenchymal Stem Cells Ameliorate Chronic Experimental Autoimmune Encephalomyelitis

(2009) Gabriela Constantin et al.   STEM CELLS

Mouse Mesenchymal Stem Cells Suppress Antigen-Specific TH Cell Immunity Independent of Indoleamine 2,3-Dioxygenase 1 (IDO1)

(2009) Tobias V. Lanz et al.   STEM CELLS AND DEVELOPMENT

Donor-Derived Brain Tumor Following Neural Stem Cell Transplantation in an Ataxia Telangiectasia Patient

(2009) Ninette Amariglio et al.   PLOS MEDICINE

Neuroprotection and Immunomodulation With Mesenchymal Stem Cells in Chronic Experimental Autoimmune Encephalomyelitis

(2008) Ibrahim Kassis et al.   ARCHIVES OF NEUROLOGY

CD4+ICOS+ T lymphocytes inhibit T cell activation ‘in vitro’ and attenuate autoimmune encephalitis ‘in vivo’

(2008) Jose M. Rojo et al.   INTERNATIONAL IMMUNOLOGY

Stem cells ameliorate EAE via an indoleamine 2,3-dioxygenase (IDO) mechanism

(2008) Mariola Matysiak et al.   JOURNAL OF NEUROIMMUNOLOGY

Overexpression of CNTF in Mesenchymal Stem Cells reduces demyelination and induces clinical recovery in experimental autoimmune encephalomyelitis mice

(2008) Zhengqi Lu et al.   JOURNAL OF NEUROIMMUNOLOGY

Neural precursor cells inhibit multiple inflammatory signals

(2008) Nina Fainstein et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Human mesenchymal stem cells abrogate experimental allergic encephalomyelitis after intraperitoneal injection, and with sparse CNS infiltration

(2008) David Gordon et al.   NEUROSCIENCE LETTERS

Neuroprotective Effect of Transplanted Human Embryonic Stem Cell-Derived Neural Precursors in an Animal Model of Multiple Sclerosis

(2008) Michal Aharonowiz et al.   PLoS One

Can cell therapy heal a spinal cord injury?

(2008) M W Ronsyn et al.   SPINAL CORD

Pulmonary Passage is a Major Obstacle for Intravenous Stem Cell Delivery: The Pulmonary First-Pass Effect

(2008) Uwe M. Fischer et al.   STEM CELLS AND DEVELOPMENT

Interleukin-27 suppresses experimental autoimmune encephalomyelitis during bone marrow stromal cell treatment

(2007) Jinghua Wang et al.   JOURNAL OF AUTOIMMUNITY