CAY10593 inhibits the human P2X7 receptor independently of phospholipase D1 stimulation

Human P2X7 receptor activation induces the rapid shedding of CXCL16

(2013) Aleta Pupovac et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

P2X7 receptor activation mediates organic cation uptake into human myeloid leukaemic KG-1 cells

(2012) Safina Gadeock et al.   Purinergic Signalling

P2X7 receptor activation induces reactive oxygen species formation in erythroid cells

(2012) Bin Wang et al.   Purinergic Signalling

Colchicine inhibits cationic dye uptake induced by ATP in P2X2 and P2X7 receptor-expressing cells: implications for its therapeutic action

(2011) C Marques-da-Silva et al.   BRITISH JOURNAL OF PHARMACOLOGY

Many ways to dilate the P2X7 receptor pore

(2011) Pablo Pelegrín   BRITISH JOURNAL OF PHARMACOLOGY

Transcriptional control mechanisms associated with the nucleotide receptor P2X7, a critical regulator of immunologic, osteogenic, and neurologic functions

(2011) Lisa Y. Lenertz et al.   IMMUNOLOGIC RESEARCH

The human P2X7 receptor and its role in innate immunity

(2011) J. S. Wiley et al.   TISSUE ANTIGENS

P2X7 receptor activation induces cell death and microparticle release in murine erythroleukemia cells

(2010) Patrick Constantinescu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

P2X7 receptor activation induces cell death and CD23 shedding in human RPMI 8226 multiple myeloma cells

(2010) Andrew W. Farrell et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Two haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1β secretion

(2010) Leanne Stokes et al.   FASEB JOURNAL

Activation of Macrophages by P2X7-Induced Microvesicles from Myeloid Cells Is Mediated by Phospholipids and Is Partially Dependent on TLR4

(2010) L. M. Thomas et al.   JOURNAL OF IMMUNOLOGY

Experimental Characterization and Mathematical Modeling of P2X7 Receptor Channel Gating

(2010) Z. Yan et al.   JOURNAL OF NEUROSCIENCE

Acid sphingomyelinase activity triggers microparticle release from glial cells

(2009) Fabio Bianco et al.   EMBO JOURNAL

P2X7 Receptor Activates Multiple Selective Dye-Permeation Pathways in RAW 264.7 and Human Embryonic Kidney 293 Cells

(2009) S. Cankurtaran-Sayar et al.   MOLECULAR PHARMACOLOGY

Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness

(2009) Sarah A Scott et al.   Nature Chemical Biology

ATP-induced P2X7-associated uptake of large molecules involves distinct mechanisms for cations and anions in macrophages

(2008) J. Schachter et al.   JOURNAL OF CELL SCIENCE

Negative and positive allosteric modulators of the P2X7receptor

(2007) A D Michel et al.   BRITISH JOURNAL OF PHARMACOLOGY