A common structural scaffold in CTD phosphatases that supports distinct catalytic mechanisms

Elucidating Human Phosphatase-Substrate Networks

(2013) X. Li et al.   Science Signaling

Regulation of A20 and other OTU deubiquitinases by reversible oxidation

(2013) Yogesh Kulathu et al.   Nature Communications

Structural and Kinetic Analysis of Prolyl-isomerization/Phosphorylation Cross-Talk in the CTD Code

(2012) Mengmeng Zhang et al.   ACS Chemical Biology

Roundup 2.0: enabling comparative genomics for over 1800 genomes

(2012) T. F. DeLuca et al.   BIOINFORMATICS

Human HAD phosphatases: structure, mechanism, and roles in health and disease

(2012) Annegrit Seifried et al.   FEBS Journal

An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72

(2012) K. Xiang et al.   GENES & DEVELOPMENT

Ssu72 Phosphatase-dependent Erasure of Phospho-Ser7 Marks on the RNA Polymerase II C-terminal Domain Is Essential for Viability and Transcription Termination

(2012) David W. Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reactive oxygen/nitrogen species and their functional correlations in neurodegenerative diseases

(2012) Mahesh Ramalingam et al.   JOURNAL OF NEURAL TRANSMISSION

A Universal RNA Polymerase II CTD Cycle Is Orchestrated by Complex Interplays between Kinase, Phosphatase, and Isomerase Enzymes along Genes

(2012) Alain R. Bataille et al.   MOLECULAR CELL

Oxidative Stress in Alzheimer's and Parkinson's Diseases: Insights from the YeastSaccharomyces cerevisiae

(2012) Catarina Pimentel et al.   Oxidative Medicine and Cellular Longevity

Updating the RNA polymerase CTD code: adding gene-specific layers

(2012) Sylvain Egloff et al.   TRENDS IN GENETICS

The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity

(2012) Kehui Xiang et al.   Nature Communications

Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue

(2011) Yong Zhang et al.   BIOCHEMICAL JOURNAL

Ser7 Phosphorylation of the CTD Recruits the RPAP2 Ser5 Phosphatase to snRNA Genes

(2011) Sylvain Egloff et al.   MOLECULAR CELL

Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription

(2011) Andres Clemente-Blanco et al.   NATURE CELL BIOLOGY

The Genomes OnLine Database (GOLD) v.4: status of genomic and metagenomic projects and their associated metadata

(2011) I. Pagani et al.   NUCLEIC ACIDS RESEARCH

The Pfam protein families database

(2011) M. Punta et al.   NUCLEIC ACIDS RESEARCH

The many blades of the β-propeller proteins: conserved but versatile

(2011) Cammy K.-M. Chen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription

(2011) María Guillamot et al.   Scientific Reports

Structural classification of proteins and structural genomics: new insights into protein folding and evolution

(2010) Antonina Andreeva et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Frozen robust multiarray analysis (fRMA)

(2010) M. N. McCall et al.   BIOSTATISTICS

cis-Proline-mediated Ser(P)5Dephosphorylation by the RNA Polymerase II C-terminal Domain Phosphatase Ssu72

(2010) Jon W. Werner-Allen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair

(2010) Annamaria Mocciaro et al.   JOURNAL OF CELL BIOLOGY

Cdc14: a highly conserved family of phosphatases with non-conserved functions?

(2010) A. Mocciaro et al.   JOURNAL OF CELL SCIENCE

Genetic Organization, Length Conservation, and Evolution of RNA Polymerase II Carboxyl-Terminal Domain

(2010) Pengda Liu et al.   MOLECULAR BIOLOGY AND EVOLUTION

Crystal structure of the human symplekin–Ssu72–CTD phosphopeptide complex

(2010) Kehui Xiang et al.   NATURE

COXPRESdb: a database to compare gene coexpression in seven model animals

(2010) T. Obayashi et al.   NUCLEIC ACIDS RESEARCH

NCBI GEO: archive for functional genomics data sets--10 years on

(2010) T. Barrett et al.   NUCLEIC ACIDS RESEARCH

The Gene Expression Barcode: leveraging public data repositories to begin cataloging the human and murine transcriptomes

(2010) Matthew N. McCall et al.   NUCLEIC ACIDS RESEARCH

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

Structural Ties between Cholesterol Transport and Morphogen Signaling

(2009) J. Fernando Bazan et al.   CELL

Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome

(2009) Alastair J. Barr et al.   CELL

Serine/Threonine Phosphatases: Mechanism through Structure

(2009) Yigong Shi   CELL

Markers of fitness in a successful enzyme superfamily

(2009) Karen N Allen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Rank of Correlation Coefficient as a Comparable Measure for Biological Significance of Gene Coexpression

(2009) T. Obayashi et al.   DNA RESEARCH

An Unusual Recent Expansion of the C-Terminal Domain of RNA Polymerase II in Primate Malaria Parasites Features a Motif Otherwise Found Only in Mammalian Polymerases

(2009) Sandeep P. Kishore et al.   JOURNAL OF MOLECULAR EVOLUTION

Functional Interaction of the Ess1 Prolyl Isomerase with Components of the RNA Polymerase II Initiation and Termination Machineries

(2009) S. Krishnamurthy et al.   MOLECULAR AND CELLULAR BIOLOGY

The Ess1 Prolyl Isomerase Is Required for Transcription Termination of Small Noncoding RNAs via the Nrd1 Pathway

(2009) Navjot Singh et al.   MOLECULAR CELL

Rtr1 Is a CTD Phosphatase that Regulates RNA Polymerase II during the Transition from Serine 5 to Serine 2 Phosphorylation

(2009) Amber L. Mosley et al.   MOLECULAR CELL

Progression through the RNA Polymerase II CTD Cycle

(2009) Stephen Buratowski   MOLECULAR CELL

Cyclebase.org: version 2.0, an updated comprehensive, multi-species repository of cell cycle experiments and derived analysis results

(2009) Nicholas Paul Gauthier et al.   NUCLEIC ACIDS RESEARCH

Challenges and Opportunities in Defining the Essential Cancer Kinome

(2009) B. D. Manning   Science Signaling

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

(2009) Chunlei Wu et al.   GENOME BIOLOGY

Evolution of protein phosphatases in plants and animals

(2008) Greg B. G. Moorhead et al.   BIOCHEMICAL JOURNAL

Oxidative Stress Signaling in Alzheimers Disease

(2008) B. Su et al.   Current Alzheimer Research

Rtr1 Is theSaccharomyces cerevisiaeHomolog of a Novel Family of RNA Polymerase II-Binding Proteins

(2008) Patrick A. Gibney et al.   EUKARYOTIC CELL

Protozoan protein tyrosine phosphatases

(2008) A ANDREEVA et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication

(2008) Jun Wu et al.   JOURNAL OF CELL BIOLOGY

The Structure of Fcp1, an Essential RNA Polymerase II CTD Phosphatase

(2008) Agnidipta Ghosh et al.   MOLECULAR CELL

CTD phosphatases in the attenuation of wound-induced transcription of jasmonic acid biosynthetic genes in Arabidopsis

(2008) Osamu Matsuda et al.   PLANT JOURNAL

The Arabidopsis thaliana carboxyl-terminal domain phosphatase-like 2 regulates plant growth, stress and auxin responses

(2008) Akihiro Ueda et al.   PLANT MOLECULAR BIOLOGY

Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

(2008) W. S. Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae

(2008) Wei Niu et al.   PLoS Genetics