Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential
Authors
Keywords
-
Journal
Nature Communications
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2015-10-27
DOI
10.1038/ncomms9620
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Autophagy and neurodegeneration
- (2015) Rebecca A. Frake et al. JOURNAL OF CLINICAL INVESTIGATION
- The role for autophagy in cancer
- (2015) Eileen White JOURNAL OF CLINICAL INVESTIGATION
- Development of autophagy inducers in clinical medicine
- (2015) Beth Levine et al. JOURNAL OF CLINICAL INVESTIGATION
- Pharmacologic agents targeting autophagy
- (2015) Helin Vakifahmetoglu-Norberg et al. JOURNAL OF CLINICAL INVESTIGATION
- Autophagy: a druggable process that is deregulated in aging and human disease
- (2015) Guido Kroemer JOURNAL OF CLINICAL INVESTIGATION
- Immunologic manifestations of autophagy
- (2015) Vojo Deretic et al. JOURNAL OF CLINICAL INVESTIGATION
- Deacetylation of Nuclear LC3 Drives Autophagy Initiation under Starvation
- (2015) Rui Huang et al. MOLECULAR CELL
- Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism
- (2015) Rushika M. Perera et al. NATURE
- Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth
- (2015) Ting Sun et al. Nature Communications
- Does bafilomycin A1block the fusion of autophagosomes with lysosomes?
- (2014) Daniel J. Klionsky et al. Autophagy
- Clinical research andAutophagy
- (2014) Daniel J Klionsky et al. Autophagy
- Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells
- (2014) Alisdair McNeill et al. BRAIN
- Molecular Basis for Age-Dependent Microtubule Acetylation by Tubulin Acetyltransferase
- (2014) Agnieszka Szyk et al. CELL
- Microtubule dynamics regulates Akt signaling via dynactin p150
- (2014) Hakryul Jo et al. CELLULAR SIGNALLING
- Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB
- (2014) V. A. Polito et al. EMBO Molecular Medicine
- Targeting γ-Herpesvirus 68 Bcl-2-mediated Down-regulation of Autophagy
- (2014) Minfei Su et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Reactive Oxygen Species, AMP-activated Protein Kinase, and the Transcription Cofactor p300 Regulate α-Tubulin Acetyltransferase-1 (αTAT-1/MEC-17)-dependent Microtubule Hyperacetylation during Cell Stress
- (2014) Rafah Mackeh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3
- (2014) Aditya Murthy et al. NATURE
- Lysosome: regulator of lipid degradation pathways
- (2014) Carmine Settembre et al. TRENDS IN CELL BIOLOGY
- PICALM modulates autophagy activity and tau accumulation
- (2014) Kevin Moreau et al. Nature Communications
- Selective Modulation of Autophagy, Innate Immunity, and Adaptive Immunity by Small Molecules
- (2013) Stanley Y. Shaw et al. ACS Chemical Biology
- Tyrosine kinase inhibition increases functional parkin-Beclin-1 interaction and enhances amyloid clearance and cognitive performance
- (2013) Irina Lonskaya et al. EMBO Molecular Medicine
- Dendritic cell dysregulation during HIV-1 infection
- (2013) Elizabeth Miller et al. IMMUNOLOGICAL REVIEWS
- Autophagy and microtubules - new story, old players
- (2013) R. Mackeh et al. JOURNAL OF CELL SCIENCE
- Identification of a candidate therapeutic autophagy-inducing peptide
- (2013) Sanae Shoji-Kawata et al. NATURE
- Tau degradation: The ubiquitin–proteasome system versus the autophagy-lysosome system
- (2013) Min Jae Lee et al. PROGRESS IN NEUROBIOLOGY
- Ambroxol as a pharmacological chaperone for mutant glucocerebrosidase
- (2012) Inna Bendikov-Bar et al. BLOOD CELLS MOLECULES AND DISEASES
- A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
- (2012) Carmine Settembre et al. EMBO JOURNAL
- Autophagy modulation as a potential therapeutic target for diverse diseases
- (2012) David C. Rubinsztein et al. NATURE REVIEWS DRUG DISCOVERY
- The Role of Atg Proteins in Autophagosome Formation
- (2011) Noboru Mizushima et al. Annual Review of Cell and Developmental Biology
- Autophagy and Aging
- (2011) David C. Rubinsztein et al. CELL
- Regulation of TFEB and V-ATPases by mTORC1
- (2011) Samuel Peña-Llopis et al. EMBO JOURNAL
- Hormonally Active Vitamin D3 (1α,25-Dihydroxycholecalciferol) Triggers Autophagy in Human Macrophages That Inhibits HIV-1 Infection
- (2011) Grant R. Campbell et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions
- (2011) Carsten Janke et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase
- (2011) R. Zoncu et al. SCIENCE
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- A reporter cell system to monitor autophagy based on p62/SQSTM1
- (2010) Kenneth Bowitz Larsen et al. Autophagy
- The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma
- (2010) P. A. Spagnuolo et al. BLOOD
- Acetylated microtubules are required for fusion of autophagosomes with lysosomes
- (2010) Rui Xie et al. BMC CELL BIOLOGY
- Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
- (2010) Yasemin Sancak et al. CELL
- Methods in Mammalian Autophagy Research
- (2010) Noboru Mizushima et al. CELL
- Human Immunodeficiency Virus-1 Inhibition of Immunoamphisomes in Dendritic Cells Impairs Early Innate and Adaptive Immune Responses
- (2010) Fabien P. Blanchet et al. IMMUNITY
- Starvation-induced Hyperacetylation of Tubulin Is Required for the Stimulation of Autophagy by Nutrient Deprivation
- (2010) Camille Geeraert et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MEC-17 is an α-tubulin acetyltransferase
- (2010) Jyothi S. Akella et al. NATURE
- Regulation of Tau Pathology by the Microglial Fractalkine Receptor
- (2010) Kiran Bhaskar et al. NEURON
- Autophagy and Metabolism
- (2010) J. D. Rabinowitz et al. SCIENCE
- Crohn's disease-associated adherent-invasiveE.âcoliare selectively favoured by impaired autophagy to replicate intracellularly
- (2009) Pierre Lapaquette et al. CELLULAR MICROBIOLOGY
- An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1
- (2009) Carson C. Thoreen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages
- (2009) George B. Kyei et al. JOURNAL OF CELL BIOLOGY
- Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6
- (2009) Y. Zilberman et al. JOURNAL OF CELL SCIENCE
- Autophagy Gene Variant IRGM −261T Contributes to Protection from Tuberculosis Caused by Mycobacterium tuberculosis but Not by M. africanum Strains
- (2009) Christopher D. Intemann et al. PLoS Pathogens
- JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy
- (2008) Yongjie Wei et al. MOLECULAR CELL
- Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
- (2008) Andrea Williams et al. Nature Chemical Biology
- Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
- (2008) Steven A McCarroll et al. NATURE GENETICS
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now