Design of a platform technology for systemic delivery of siRNA to tumours using rolling circle transcription

siRNA Conjugates Carrying Sequentially Assembled Trivalent N-Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing In Vivo in Hepatocytes

(2015) Shigeo Matsuda et al.   ACS Chemical Biology

Smart functional nucleic acid chimeras: Enabling tissue specific RNA targeting therapy

(2015) Lukas J Aaldering et al.   RNA Biology

Preclinical and early clinical development of GNbAC1, a humanized IgG4 monoclonal antibody targeting endogenous retroviral MSRV-Env protein

(2014) François Curtin et al.   mAbs

Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB–siRNA conjugates

(2014) Trinna L. Cuellar et al.   NUCLEIC ACIDS RESEARCH

Effect of Folate-Targeted Nanoparticle Size on Their Rates of Penetration into Solid Tumors

(2013) Erina Vlashi et al.   ACS Nano

RNAi-Microsponges Form through Self-Assembly of the Organic and Inorganic Products of Transcription

(2013) Kevin E. Shopsowitz et al.   Small

Lipid nanoparticle delivery systems for siRNA-based therapeutics

(2013) C. Wan et al.   Drug Delivery and Translational Research

Tumor-Homing Poly-siRNA/Glycol Chitosan Self-Cross-Linked Nanoparticles for Systemic siRNA Delivery in Cancer Treatment

(2012) So Jin Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural modification of siRNA for efficient gene silencing

(2012) So Jin Lee et al.   BIOTECHNOLOGY ADVANCES

Nanodelivery strategies in cancer chemotherapy: biological rationale and pharmaceutical perspectives

(2012) George Mattheolabakis et al.   Nanomedicine

Self-assembled RNA interference microsponges for efficient siRNA delivery

(2012) Jong Bum Lee et al.   NATURE MATERIALS

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

Tumor-Targeted Drug Delivery with Aptamers

(2011) Y. Zhang et al.   CURRENT MEDICINAL CHEMISTRY

The Origin of Cholesterol’s Condensing Effect

(2011) Trevor A. Daly et al.   LANGMUIR

Delivery of siRNA Therapeutics: Barriers and Carriers

(2010) Jie Wang et al.   AAPS Journal

Biodegradable Block Copolymer-Doxorubicin Conjugates via Different Linkages: Preparation, Characterization, and In Vitro Evaluation

(2010) Xiuli Hu et al.   BIOMACROMOLECULES

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Rational design of cationic lipids for siRNA delivery

(2010) Sean C Semple et al.   NATURE BIOTECHNOLOGY

Erratum: Knocking down barriers: advances in siRNA delivery

(2010) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Shielding effect of monovalent and divalent cations on solid-phase DNA hybridization: surface plasmon resonance biosensor study

(2010) Tomáš Špringer et al.   NUCLEIC ACIDS RESEARCH

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

siRNA and Innate Immunity

(2009) Marjorie Robbins et al.   OLIGONUCLEOTIDES

In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(–PEG)/siRNA complexes

(2009) Anastasia Malek et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY