GTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated state
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Title
GTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated state
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 111, Issue 18, Pages E1843-E1851
Publisher
Proceedings of the National Academy of Sciences
Online
2014-04-22
DOI
10.1073/pnas.1401706111
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Related references
Note: Only part of the references are listed.- GTP Is the Primary Activator of the Anti-HIV Restriction Factor SAMHD1
- (2013) Sarah M. Amie et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tetramerization of SAMHD1 Is Required for Biological Activity and Inhibition of HIV Infection
- (2013) Junpeng Yan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SAMHD1 Restricts Herpes Simplex Virus 1 in Macrophages by Limiting DNA Replication
- (2013) Eui Tae Kim et al. JOURNAL OF VIROLOGY
- Mechanism of allosteric activation of SAMHD1 by dGTP
- (2013) Xiaoyun Ji et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Uracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents viral integration
- (2013) A. F. Weil et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cost of rNTP/dNTP pool imbalance at the replication fork
- (2013) N. Y. Yao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells
- (2013) E. Franzolin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation of SAMHD1 by Cyclin A2/CDK1 Regulates Its Restriction Activity toward HIV-1
- (2013) Alexandra Cribier et al. Cell Reports
- SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates
- (2012) Hichem Lahouassa et al. NATURE IMMUNOLOGY
- SAMHD1 restricts HIV-1 infection in resting CD4+ T cells
- (2012) Hanna-Mari Baldauf et al. NATURE MEDICINE
- High Inorganic Triphosphatase Activities in Bacteria and Mammalian Cells: Identification of the Enzymes Involved
- (2012) Gregory Kohn et al. PLoS One
- Characterization of the Deoxynucleotide Triphosphate Triphosphohydrolase (dNTPase) Activity of the EF1143 Protein fromEnterococcus faecalisand Crystal Structure of the Activator-Substrate Complex
- (2011) Ivan I. Vorontsov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Abundant Non-canonical dUTP Found in Primary Human Macrophages Drives Its Frequent Incorporation by HIV-1 Reverse Transcriptase
- (2011) Edward M. Kennedy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Aicardi-Goutières Syndrome Gene and HIV-1 Restriction Factor SAMHD1 Is a dGTP-regulated Deoxynucleotide Triphosphohydrolase
- (2011) Rebecca D. Powell et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
- (2011) David C. Goldstone et al. NATURE
- Regulation by degradation, a cellular defense against deoxyribonucleotide pool imbalances
- (2010) Chiara Rampazzo et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
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