Role of acid sphingomyelinase bioactivity in human CD4+ T-cell activation and immune responses

CD39 and CD161 Modulate Th17 Responses in Crohn's Disease

(2014) Aiping Bai et al.   JOURNAL OF IMMUNOLOGY

P2X7 Integrates PI3K/AKT and AMPK-PRAS40-mTOR Signaling Pathways to Mediate Tumor Cell Death

(2013) Shu Bian et al.   PLoS One

Different features of lung involvement in Niemann-Pick disease and Gaucher disease

(2012) Bora Gülhan et al.   RESPIRATORY MEDICINE

C6-ceramide enhances Interleukin-12-mediated T helper type 1 cell responses through a cyclooxygenase-2-dependent pathway

(2011) Chin Siang Kue et al.   IMMUNOBIOLOGY

Regulation of NF-κB induction by TCR/CD28

(2011) Jing Cheng et al.   IMMUNOLOGIC RESEARCH

Ceramides as modulators of cellular and whole-body metabolism

(2011) Benjamin T. Bikman et al.   JOURNAL OF CLINICAL INVESTIGATION

Acid Sphingomyelinase Is Required for Protection of Effector Memory T Cells against Glucocorticoid-Induced Cell Death

(2011) D. Tischner et al.   JOURNAL OF IMMUNOLOGY

Genetics and pathogenesis of inflammatory bowel disease

(2011) Bernard Khor et al.   NATURE

AMPK agonist downregulates innate and adaptive immune responses in TNBS-induced murine acute and relapsing colitis

(2010) Aiping Bai et al.   BIOCHEMICAL PHARMACOLOGY

Metabolism in T cell activation and differentiation

(2010) Erika L Pearce   CURRENT OPINION IN IMMUNOLOGY

Synergistic and combinatorial control of T cell activation and differentiation by transcription factors

(2010) Mark S Sundrud et al.   CURRENT OPINION IN IMMUNOLOGY

Vitamin D controls T cell antigen receptor signaling and activation of human T cells

(2010) Marina Rode von Essen et al.   NATURE IMMUNOLOGY

Defective Acid Sphingomyelinase Pathway withPseudomonas aeruginosaInfection in Cystic Fibrosis

(2009) Hong Yu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Acid sphingomyelinase, cell membranes and human disease: Lessons from Niemann-Pick disease

(2009) Edward H. Schuchman   FEBS LETTERS

Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease

(2009) S. Brand   GUT

RNA Interference Screen in Primary Human T Cells Reveals FLT3 as a Modulator of IL-10 Levels

(2009) A. L. Astier et al.   JOURNAL OF IMMUNOLOGY

All-trans retinoic acid down-regulates inflammatory responses by shifting the Treg/Th17 profile in human ulcerative and murine colitis

(2009) Aiping Bai et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes

(2009) Jasmin Herz et al.   NATURE IMMUNOLOGY

Lipid Alterations in Experimental Murine Colitis: Role of Ceramide and Imipramine for Matrix Metalloproteinase-1 Expression

(2009) Jessica Bauer et al.   PLoS One

Improved Pulmonary Function by Acid Sphingomyelinase Inhibition in a Newborn Piglet Lavage Model

(2008) Philipp von Bismarck et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ceramide-enriched membrane domains—Structure and function

(2008) Yang Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The unexpected role of acid sphingomyelinase in cell death and the pathophysiology of common diseases

(2008) Eric L. Smith et al.   FASEB JOURNAL