Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation

Mitochondrially Targeted Vitamin E Succinate Modulates Expression of Mitochondrial DNA Transcripts and Mitochondrial Biogenesis

(2015) Jaroslav Truksa et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Ca2+ influx targets cardiolipin to disintegrate respiratory chain complex II for cell death induction

(2014) M-S Hwang et al.   CELL DEATH AND DIFFERENTIATION

Inhibition of mitochondrial glycerol-3-phosphate dehydrogenase by α-tocopheryl succinate

(2014) Hana Rauchová et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Structural Re-arrangement and Peroxidase Activation of Cytochromecby Anionic Analogues of Vitamin E, Tocopherol Succinate and Tocopherol Phosphate

(2014) Naveena Yanamala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Powerhouse down: Complex II dissociation in the respiratory chain

(2014) Ming-Shih Hwang et al.   MITOCHONDRION

A semi-automated method for isolating functionally intact mitochondria from cultured cells and tissue biopsies

(2013) Sabine Schmitt et al.   ANALYTICAL BIOCHEMISTRY

Q-site inhibitor induced ROS production of mitochondrial complex II is attenuated by TCA cycle dicarboxylates

(2013) Ilka Siebels et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Differential effects of complex II on mitochondrial ROS production and their relation to cardioprotective pre- and postconditioning

(2013) Stefan Dröse   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Overexpression of the antioxidant enzyme catalase does not interfere with the glucose responsiveness of insulin-secreting INS-1E cells and rat islets

(2013) S. Lortz et al.   DIABETOLOGIA

Molecular mechanism for the selective impairment of cancer mitochondrial function by a mitochondrially targeted vitamin E analogue

(2012) Sara Rodríguez-Enríquez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Respiratory chain complex II as general sensor for apoptosis

(2012) Stefan Grimm   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial complex II, a novel target for anti-cancer agents

(2012) Katarina Kluckova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Catalytic mechanisms of complex II enzymes: A structural perspective

(2012) T.M. Iverson   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions

(2012) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

OpenMM 4: A Reusable, Extensible, Hardware Independent Library for High Performance Molecular Simulation

(2012) Peter Eastman et al.   Journal of Chemical Theory and Computation

Classification of mitocans, anti-cancer drugs acting on mitochondria

(2012) Jiri Neuzil et al.   MITOCHONDRION

In vitro inhibition of mitochondrial respiratory rate by antidepressants

(2012) Jana Hroudová et al.   TOXICOLOGY LETTERS

Anticancer Drugs Targeting the Mitochondrial Electron Transport Chain

(2011) Jakub Rohlena et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrially Targeted α-Tocopheryl Succinate Is Antiangiogenic: Potential Benefit Against Tumor Angiogenesis but Caution Against Wound Healing

(2011) Jakub Rohlena et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy

(2011) Lan-Feng Dong et al.   FREE RADICAL BIOLOGY AND MEDICINE

Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson’s disease model

(2011) Won-Seok Choi et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer?

(2011) A Lemarie et al.   ONCOGENE

The quinone-binding and catalytic site of complex II

(2010) Elena Maklashina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Calcium signalling-dependent mitochondrial dysfunction and bioenergetics regulation in respiratory chain Complex II deficiency

(2010) E Mbaya et al.   CELL DEATH AND DIFFERENTIATION

Specific disintegration of complex II succinate:ubiquinone oxidoreductase links pH changes to oxidative stress for apoptosis induction

(2010) A Lemarie et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial Targeting of Vitamin E Succinate Enhances Its Pro-apoptotic and Anti-cancer Activity via Mitochondrial Complex II

(2010) Lan-Feng Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of Tumor Growth In vivo by the Mitocan  -tocopheryl Succinate Requires Respiratory Complex II

(2009) L.-F. Dong et al.   CLINICAL CANCER RESEARCH

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates

(2008) Florian L. Muller et al.   BIOCHEMICAL JOURNAL

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II

(2008) L-F Dong et al.   ONCOGENE