Mitochondrially Targeted α-Tocopheryl Succinate Is Antiangiogenic: Potential Benefit Against Tumor Angiogenesis but Caution Against Wound Healing

Hippo/Mst1 Stimulates Transcription of the Proapoptotic Mediator NOXA in a FoxO1-Dependent Manner

(2011) K. Valis et al.   CANCER RESEARCH

Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy

(2011) Lan-Feng Dong et al.   FREE RADICAL BIOLOGY AND MEDICINE

α-Tocopheryl succinate causes mitochondrial permeabilization by preferential formation of Bak channels

(2010) Lubomir Prochazka et al.   APOPTOSIS

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Mitochondrial Targeting of Vitamin E Succinate Enhances Its Pro-apoptotic and Anti-cancer Activity via Mitochondrial Complex II

(2010) Lan-Feng Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients

(2010) Edward J. Gane et al.   LIVER INTERNATIONAL

A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease

(2010) Barry J. Snow et al.   MOVEMENT DISORDERS

Targeting mitochondria for cancer therapy

(2010) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Hypoxia inducible microRNA 210 attenuates keratinocyte proliferation and impairs closure in a murine model of ischemic wounds

(2010) S. Biswas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suppression of Tumor Growth In vivo by the Mitocan  -tocopheryl Succinate Requires Respiratory Complex II

(2009) L.-F. Dong et al.   CLINICAL CANCER RESEARCH

Mitochondria as targets in angiogenesis inhibition

(2009) Danielle Park et al.   MOLECULAR ASPECTS OF MEDICINE

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Characterization of a preclinical model of chronic ischemic wound

(2009) Sashwati Roy et al.   PHYSIOLOGICAL GENOMICS

α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II

(2008) L-F Dong et al.   ONCOGENE

Mitochondria in cancer cells: what is so special about them?

(2008) Vladimir Gogvadze et al.   TRENDS IN CELL BIOLOGY