Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody

Human protective response induced by meningococcus B vaccine is mediated by the synergy of multiple bactericidal epitopes

(2018) M. Giuliani et al.   Scientific Reports

Emerging experience with meningococcal serogroup B protein vaccines

(2017) Daniela Toneatto et al.   Expert Review of Vaccines

The role of anti-NHba antibody in bactericidal activity elicited by the meningococcal serogroup B vaccine, MenB-4C

(2017) Elizabeth Partridge et al.   VACCINE

Crystal structures of human Fabs targeting the Bexsero meningococcal vaccine antigen NHBA

(2017) Martina Maritan et al.   Acta Crystallographica Section F-Structural Biology Communications

Neisseria meningitidis factor H-binding protein bound to monoclonal antibody JAR5: implications for antibody synergy

(2016) E. Malito et al.   BIOCHEMICAL JOURNAL

Epitope Mapping of a Monoclonal Antibody Directed against Neisserial Heparin Binding Antigen Using Next Generation Sequencing of Antigen-Specific Libraries

(2016) Maria Domina et al.   PLoS One

Protein stability: a crystallographer's perspective

(2016) Marc C. Deller et al.   Acta Crystallographica Section F-Structural Biology Communications

Neisserial Heparin Binding Antigen (NHBA) Contributes to the Adhesion of Neisseria meningitidis to Human Epithelial Cells

(2016) Irene Vacca et al.   PLoS One

Neisseria meningitis GNA1030 is a ubiquinone-8 binding protein

(2015) Danilo Donnarumma et al.   FASEB JOURNAL

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

JPred4: a protein secondary structure prediction server

(2015) Alexey Drozdetskiy et al.   NUCLEIC ACIDS RESEARCH

A meningococcal vaccine antigen engineered to increase thermal stability and stabilize protective epitopes

(2015) Monica Konar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MoRDa, an automatic molecular replacement pipeline

(2015) Alexey Vagin et al.   Acta Crystallographica A-Foundation and Advances

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

(2014) Enrico Malito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The C2 fragment fromNeisseria meningitidisantigen NHBA increases endothelial permeability by destabilizing adherens junctions

(2013) Alessandro Casellato et al.   CELLULAR MICROBIOLOGY

A Multi-Component Meningococcal Serogroup B Vaccine (4CMenB): The Clinical Development Program

(2013) Miguel O’Ryan et al.   DRUGS

Scalable web services for the PSIPRED Protein Analysis Workbench

(2013) Daniel W. A. Buchan et al.   NUCLEIC ACIDS RESEARCH

Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

(2013) Enrico Malito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conservation of Meningococcal Antigens in the Genus Neisseria

(2013) A. Muzzi et al.   mBio

A Systematic Comparison of Free and Bound Antibodies Reveals Binding-Related Conformational Changes

(2012) I. Sela-Culang et al.   JOURNAL OF IMMUNOLOGY

The new multicomponent vaccine against meningococcal serogroup B, 4CMenB: Immunological, functional and structural characterization of the antigens

(2012) Davide Serruto et al.   VACCINE

Meningococcal disease: Clinical presentation and sequelae

(2012) David Pace et al.   VACCINE

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure of the uncomplexedNeisseria meningitidisfactor H-binding protein fHbp (rLP2086)

(2011) Laura Cendron et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Structure of the C-terminal Domain ofNeisseriaHeparin Binding Antigen (NHBA), One of the Main Antigens of a Novel Vaccine againstNeisseria meningitidis

(2011) Veronica Esposito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural analysis of intrinsically disordered proteins by small-angle X-ray scattering

(2011) Pau Bernadó et al.   Molecular BioSystems

Modeling Disordered Regions in Proteins Using Rosetta

(2011) Ray Yu-Ruei Wang et al.   PLoS One

Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity

(2011) M. Scarselli et al.   Science Translational Medicine

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans

(2010) Davide Serruto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solution Structure of the Factor H-binding Protein, a Survival Factor and Protective Antigen ofNeisseria meningitidis

(2009) Francesca Cantini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates

(2009) Muriel C. Schneider et al.   NATURE

Global epidemiology of meningococcal disease

(2009) Lee H. Harrison et al.   VACCINE

Combining the polymerase incomplete primer extension method for cloning and mutagenesis with microscreening to accelerate structural genomics efforts

(2007) Heath E. Klock et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS