In vitro enteroid-derived three-dimensional tissue model of human small intestinal epithelium with innate immune responses

Human Gut-On-A-Chip Supports Polarized Infection of Coxsackie B1 Virus In Vitro

(2017) Remi Villenave et al.   PLoS One

Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology

(2016) Jennifer Foulke-Abel et al.   GASTROENTEROLOGY

Designer matrices for intestinal stem cell and organoid culture

(2016) Nikolce Gjorevski et al.   NATURE

Human mini-guts: new insights into intestinal physiology and host–pathogen interactions

(2016) Julie G. In et al.   Nature Reviews Gastroenterology & Hepatology

Replication of human noroviruses in stem cell-derived human enteroids

(2016) K. Ettayebi et al.   SCIENCE

Development of an Advanced Primary HumanIn VitroModel of the Small Intestine

(2016) Matthias Schweinlin et al.   TISSUE ENGINEERING PART C-METHODS

The Use of Silk as a Scaffold for Mature, Sustainable Unilocular Adipose 3D Tissue Engineered Systems

(2016) Rosalyn D. Abbott et al.   Advanced Healthcare Materials

Generating human intestinal tissues from pluripotent stem cells to study development and disease

(2015) K. L. Sinagoga et al.   EMBO JOURNAL

Three-Dimensional Cell Culture: A Breakthrough in Vivo

(2015) Delphine Antoni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology

(2015) Nicholas C. Zachos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology

(2015) Kapil Saxena et al.   JOURNAL OF VIROLOGY

How bacterial pathogens colonize their hosts and invade deeper tissues

(2015) David Ribet et al.   MICROBES AND INFECTION

Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease

(2015) S C Nalle et al.   Mucosal Immunology

The global burden of IBD: from 2015 to 2025

(2015) Gilaad G. Kaplan   Nature Reviews Gastroenterology & Hepatology

Gut biogeography of the bacterial microbiota

(2015) Gregory P. Donaldson et al.   NATURE REVIEWS MICROBIOLOGY

Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip

(2015) Hyun Jung Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Robust bioengineered 3D functional human intestinal epithelium

(2015) Ying Chen et al.   Scientific Reports

Synthetic small intestinal scaffolds for improved studies of intestinal differentiation

(2014) Cait M. Costello et al.   BIOTECHNOLOGY AND BIOENGINEERING

Toll-like receptor expression in crypt epithelial cells, putative stem cells and intestinal myofibroblasts isolated from controls and patients with inflammatory bowel disease

(2014) M. Brown et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Three dimensional human small intestine models for ADME-Tox studies

(2014) Jiajie Yu et al.   DRUG DISCOVERY TODAY

Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays

(2014) Kelli L VanDussen et al.   GUT

Toll-like receptor 6 stimulation promotes T-helper 1 and 17 responses in gastrointestinal-associated lymphoid tissue and modulates murine experimental colitis

(2014) M E Morgan et al.   Mucosal Immunology

The gut microbiota, bacterial metabolites and colorectal cancer

(2014) Petra Louis et al.   NATURE REVIEWS MICROBIOLOGY

Intestinal Subepithelial Myofibroblasts Support the Growth of Intestinal Epithelial Stem Cells

(2014) Nan Ye Lei et al.   PLoS One

Hollow fiber culture accelerates differentiation of Caco-2 cells

(2013) Xudong Deng et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Tissue Engineering the Small Intestine

(2013) Ryan G. Spurrier et al.   Clinical Gastroenterology and Hepatology

Human Primary Intestinal Epithelial Cells as an ImprovedIn VitroModel for Cryptosporidium parvum Infection

(2013) Alejandro Castellanos-Gonzalez et al.   INFECTION AND IMMUNITY

Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation

(2013) Hyun Jung Kim et al.   Integrative Biology

Alternative functional in vitro models of human intestinal epithelia

(2013) Amanda L. Kauffman et al.   Frontiers in Pharmacology

Engineering microscale topographies to control the cell–substrate interface

(2012) Mehdi Nikkhah et al.   BIOMATERIALS

A decade of change

(2012) John Arrowsmith   NATURE REVIEWS DRUG DISCOVERY

Tissue Engineering and Regenerative Medicine: Recent Innovations and the Transition to Translation

(2012) Matthew B. Fisher et al.   TISSUE ENGINEERING PART B-REVIEWS

The rate of oxygen utilization by cells

(2011) Brett A. Wagner et al.   FREE RADICAL BIOLOGY AND MEDICINE

Intestinal microbiota in human health and disease: the impact of probiotics

(2011) Jacoline Gerritsen et al.   Genes and Nutrition

Variants of NOD1 and NOD2 genes display opposite associations with familial risk of crohnʼs disease and anti-saccharomyces cerevisiae antibody levels

(2011) Francis Vasseur et al.   INFLAMMATORY BOWEL DISEASES

Materials fabrication from Bombyx mori silk fibroin

(2011) Danielle N Rockwood et al.   Nature Protocols

High-sensitivity C-reactive protein in paediatric inflammatory bowel disease

(2010) Marianne Sidoroff   WORLD JOURNAL OF GASTROENTEROLOGY

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Mucosal Gene Expression of Antimicrobial Peptides in Inflammatory Bowel Disease Before and After First Infliximab Treatment

(2009) Ingrid Arijs et al.   PLoS One

The Caco-2 cell monolayer: usefulness and limitations

(2008) Huadong Sun et al.   Expert Opinion on Drug Metabolism & Toxicology

Activation of an IL-6:STAT3-dependent transcriptome in pediatric-onset inflammatory bowel disease

(2007) Rebecca Carey et al.   INFLAMMATORY BOWEL DISEASES