Tissue Engineering and Regenerative Medicine: Recent Innovations and the Transition to Translation

Organized nanofibrous scaffolds that mimic the macroscopic and microscopic architecture of the knee meniscus

(2012) Matthew B. Fisher et al.   Acta Biomaterialia

The Effect of Platelet-Rich Fibrin Matrix on Rotator Cuff Tendon Healing

(2012) Scott A. Rodeo et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Macrophage polarization: An opportunity for improved outcomes in biomaterials and regenerative medicine

(2012) Bryan N. Brown et al.   BIOMATERIALS

MicroRNA-Mediated In Vitro and In Vivo Direct Reprogramming of Cardiac Fibroblasts to Cardiomyocytes

(2012) Tilanthi M. Jayawardena et al.   CIRCULATION RESEARCH

The evolving field of induced pluripotency: Recent progress and future challenges

(2012) Cesar A. Sommer et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial

(2012) Raj R Makkar et al.   LANCET

Heart repair by reprogramming non-myocytes with cardiac transcription factors

(2012) Kunhua Song et al.   NATURE

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

(2012) Li Qian et al.   NATURE

Skin shedding and tissue regeneration in African spiny mice (Acomys)

(2012) Ashley W. Seifert et al.   NATURE

Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues

(2012) Jordan S. Miller et al.   NATURE MATERIALS

Engineering bone tissue from human embryonic stem cells

(2012) D. Marolt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells

(2012) B. O. Diekman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular mechanical properties reflect the differentiation potential of adipose-derived mesenchymal stem cells

(2012) R. D. Gonzalez-Cruz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bioinspired nanofibers support chondrogenesis for articular cartilage repair

(2012) J. M. Coburn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sacrificial nanofibrous composites provide instruction without impediment and enable functional tissue formation

(2012) B. M. Baker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Stem Cell-Based Approach to Cartilage Repair

(2012) K. Johnson et al.   SCIENCE

Thick Acellular Heart Extracellular Matrix with Inherent Vasculature: A Potential Platform for Myocardial Tissue Regeneration

(2012) Udi Sarig et al.   TISSUE ENGINEERING PART A

Anisotropic Fibrous Scaffolds for Articular Cartilage Regeneration

(2012) Seth D. McCullen et al.   TISSUE ENGINEERING PART A

In Vivo and In Vitro Comparison of Three Different Allografts Vitalized with Human Mesenchymal Stromal Cells

(2012) Laura Coquelin et al.   TISSUE ENGINEERING PART A

Functional Recovery of Completely Denervated Muscle: Implications for Innervation of Tissue-Engineered Muscle

(2012) Sung-Bum Kang et al.   TISSUE ENGINEERING PART A

Ongoing Positive Effect of Platelet-Rich Plasma Versus Corticosteroid Injection in Lateral Epicondylitis

(2011) Taco Gosens et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Controlled activation of morphogenesis to generate a functional human microvasculature in a synthetic matrix

(2011) D. Hanjaya-Putra et al.   BLOOD

Bone Marrow-Derived Cell Therapy Stimulates Endogenous Cardiomyocyte Progenitors and Promotes Cardiac Repair

(2011) Francesco S. Loffredo et al.   Cell Stem Cell

Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency

(2011) Frederick Anokye-Danso et al.   Cell Stem Cell

Reprogramming of Mouse and Human Cells to Pluripotency Using Mature MicroRNAs

(2011) Norikatsu Miyoshi et al.   Cell Stem Cell

An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice

(2011) Anca Sindrilaru et al.   JOURNAL OF CLINICAL INVESTIGATION

Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair

(2011) S. Lee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Potential of healing a transected anterior cruciate ligament with genetically modified extracellular matrix bioscaffolds in a goat model

(2011) Matthew B. Fisher et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Deformability-based cell classification and enrichment using inertial microfluidics

(2011) Soojung Claire Hur et al.   LAB ON A CHIP

Tissue-engineered autologous urethras for patients who need reconstruction: an observational study

(2011) Atlantida Raya-Rivera et al.   LANCET

Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial

(2011) Roberto Bolli et al.   LANCET

Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip

(2011) Yuval Rinkevich et al.   NATURE

Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

(2011) Ryan Lister et al.   NATURE

Immunogenicity of induced pluripotent stem cells

(2011) Tongbiao Zhao et al.   NATURE

De novo cardiomyocytes from within the activated adult heart after injury

(2011) Nicola Smart et al.   NATURE

Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors

(2011) Pengyu Huang et al.   NATURE

A functionally characterized test set of human induced pluripotent stem cells

(2011) Gabriella L Boulting et al.   NATURE BIOTECHNOLOGY

Nanofibrous hollow microspheres self-assembled from star-shaped polymers as injectable cell carriers for knee repair

(2011) Xiaohua Liu et al.   NATURE MATERIALS

Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-γ agonists

(2011) Kengo Shimono et al.   NATURE MEDICINE

The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice

(2011) W. Tang et al.   SCIENCE

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

Readily Available Tissue-Engineered Vascular Grafts

(2011) S. L. M. Dahl et al.   Science Translational Medicine

Development and Characterization of Acellular Allogeneic Arterial Matrices

(2011) Stacy-Paul Wilshaw et al.   TISSUE ENGINEERING PART A

Mesenchymal Stem Cell Delivery into Rat Infarcted Myocardium Using a Porous Polysaccharide-Based Scaffold: A Quantitative Comparison With Endocardial Injection

(2011) Catherine Le Visage et al.   TISSUE ENGINEERING PART A

Initial Binding and Recellularization of Decellularized Mouse Lung Scaffolds with Bone Marrow-Derived Mesenchymal Stromal Cells

(2011) Amanda B. Daly et al.   TISSUE ENGINEERING PART A

Selective Removal of Undifferentiated Human Embryonic Stem Cells Using Magnetic Activated Cell Sorting Followed by a Cytotoxic Antibody

(2011) Kornelia Schriebl et al.   TISSUE ENGINEERING PART A

Repair of Rabbit Osteochondral Defects by an Acellular Technique with an Ultrapurified Alginate Gel Containing Stromal Cell-Derived Factor-1

(2011) Atsushi Sukegawa et al.   TISSUE ENGINEERING PART A

Three-Dimensional Engineered Bone–Ligament–Bone Constructs for Anterior Cruciate Ligament Replacement

(2011) Jinjin Ma et al.   TISSUE ENGINEERING PART A

Therapeutic Applications of Mesenchymal Stromal Cells: Paracrine Effects and Potential Improvements

(2011) Joyce Doorn et al.   TISSUE ENGINEERING PART B-REVIEWS

Platelet-Rich Plasma Augmentation for Arthroscopic Rotator Cuff Repair

(2010) Roberto Castricini et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Positive Effect of an Autologous Platelet Concentrate in Lateral Epicondylitis in a Double-Blind Randomized Controlled Trial

(2010) Joost C. Peerbooms et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects

(2010) Yash M. Kolambkar et al.   BIOMATERIALS

Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA

(2010) Luigi Warren et al.   Cell Stem Cell

Relative Roles of Direct Regeneration Versus Paracrine Effects of Human Cardiosphere-Derived Cells Transplanted Into Infarcted Mice

(2010) Isotta Chimenti et al.   CIRCULATION RESEARCH

Induced pluripotency: history, mechanisms, and applications

(2010) M. Stadtfeld et al.   GENES & DEVELOPMENT

Platelet-Rich Plasma Injection for Chronic Achilles Tendinopathy

(2010) Robert J. de Vos et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Regeneration of the articular surface of the rabbit synovial joint by cell homing: a proof of concept study

(2010) Chang H Lee et al.   LANCET

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

(2010) Mariela Jaskelioff et al.   NATURE

Nuclear reprogramming to a pluripotent state by three approaches

(2010) Shinya Yamanaka et al.   NATURE

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

(2010) Aaron W. B. Joe et al.   NATURE CELL BIOLOGY

Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix

(2010) Basak E Uygun et al.   NATURE MEDICINE

Regeneration and orthotopic transplantation of a bioartificial lung

(2010) Harald C Ott et al.   NATURE MEDICINE

Limbal Stem-Cell Therapy and Long-Term Corneal Regeneration

(2010) Paolo Rama et al.   NEW ENGLAND JOURNAL OF MEDICINE

Osteoinductive ceramics as a synthetic alternative to autologous bone grafting

(2010) H. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Supramolecular design of self-assembling nanofibers for cartilage regeneration

(2010) Ramille N. Shah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Active scaffolds for on-demand drug and cell delivery

(2010) X. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production

(2010) E. Boilard et al.   SCIENCE

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

Tissue-Engineered Lungs for in Vivo Implantation

(2010) T. H. Petersen et al.   SCIENCE

Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury

(2010) Ruenn Chai Lai et al.   Stem Cell Research

Controlling Stem Cell Fate with Material Design

(2009) Ross A. Marklein et al.   ADVANCED MATERIALS

In situ elasticity modulation with dynamic substrates to direct cell phenotype

(2009) April M. Kloxin et al.   BIOMATERIALS

The regulation of tendon stem cell differentiation by the alignment of nanofibers

(2009) Zi Yin et al.   BIOMATERIALS

Reprogramming towards pluripotency requires AID-dependent DNA demethylation

(2009) Nidhi Bhutani et al.   NATURE

Origins

(2009)   TISSUE ENGINEERING PART A

Induced pluripotent stem cells: current progress and potential for regenerative medicine

(2009) Giovanni Amabile et al.   TRENDS IN MOLECULAR MEDICINE

Extracellular matrix as a biological scaffold material: Structure and function

(2008) S BADYLAK et al.   Acta Biomaterialia

Clinical transplantation of a tissue-engineered airway

(2008) Paolo Macchiarini et al.   LANCET

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET

Genome-scale DNA methylation maps of pluripotent and differentiated cells

(2008) Alexander Meissner et al.   NATURE

Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors

(2008) K. Okita et al.   SCIENCE

Great Expectations: Private Sector Activity in Tissue Engineering, Regenerative Medicine, and Stem Cell Therapeutics

(2008) Michael J. Lysaght et al.   TISSUE ENGINEERING PART A