Cyclophosphamide leads to persistent deficits in physical performance and in vivo mitochondria function in a mouse model of chemotherapy late effects

Cancer-Related Fatigue

(2017) Ann M. Berger et al.   Journal of the National Comprehensive Cancer Network

Physical Activity, Fitness, and Cardiometabolic Risk Factors in Adult Survivors of Childhood Cancer with a History of Hematopoietic Cell Transplantation

(2015) Megan E. Slater et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Chemoprotective effect of vitamin E in cyclophosphamide-induced hepatotoxicity in rats

(2015) Gokhan Cuce et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Skeletal muscle mitochondrial DNA deletions are not increased in CuZn-superoxide dismutase deficient mice

(2015) Jonathan Wanagat et al.   EXPERIMENTAL GERONTOLOGY

Reduced insulin sensitivity in childhood survivors of haematopoietic stem cell transplantation is associated with lipodystropic and sarcopenic phenotypes

(2015) Christina Wei et al.   PEDIATRIC BLOOD & CANCER

Molecular Mechanisms of Acrolein Toxicity: Relevance to Human Disease

(2015) Akshata Moghe et al.   TOXICOLOGICAL SCIENCES

Anthracycline-containing chemotherapy causes long-term impairment of mitochondrial respiration and increased reactive oxygen species release in skeletal muscle

(2015) Gilles Gouspillou et al.   Scientific Reports

Ginseng alleviates cyclophosphamide-induced hepatotoxicity via reversing disordered homeostasis of glutathione and bile acid

(2015) He Zhu et al.   Scientific Reports

Ghrelin prevents tumour- and cisplatin-induced muscle wasting: characterization of multiple mechanisms involved

(2015) Ji-an Chen et al.   Journal of Cachexia Sarcopenia and Muscle

Mechanisms of Fatal Cardiotoxicity following High-Dose Cyclophosphamide Therapy and a Method for Its Prevention

(2015) Takuro Nishikawa et al.   PLoS One

Frailty in childhood cancer survivors

(2014) Kirsten K. Ness et al.   CANCER

Trajectory of overall health from self-report and factors contributing to health declines among cancer survivors

(2014) Jessica L. Petrick et al.   CANCER CAUSES & CONTROL

Acrolein-Induced Oxidative Stress and Cell Death Exhibiting Features of Apoptosis in the Yeast Saccharomyces cerevisiae Deficient in SOD1

(2014) Magdalena Kwolek-Mirek et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Muscle Atrophy in Response to Cytotoxic Chemotherapy Is Dependent on Intact Glucocorticoid Signaling in Skeletal Muscle

(2014) Theodore P. Braun et al.   PLoS One

Functional status declines among cancer survivors: Trajectory and contributing factors

(2014) Jessica L. Petrick et al.   Journal of Geriatric Oncology

Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice

(2013) Michael P. Siegel et al.   AGING CELL

Targeted enrichment and high-resolution digital profiling of mitochondrial DNA deletions in human brain

(2013) Sean D. Taylor et al.   AGING CELL

Activity of Dexrazoxane and Amifostine Against Late Cardiotoxicity Induced by the Combination of Doxorubicin and CyclophosphamideIn Vivo

(2013) Snezana K. Bjelogrlic et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Relationship of Body Mass Index and Arm Anthropometry to Outcomes after Pediatric Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies

(2013) Paul A. Hoffmeister et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

The effects of acetaldehyde and acrolein on muscle catabolism in C2 myotubes

(2013) Oren Rom et al.   FREE RADICAL BIOLOGY AND MEDICINE

The anticancer agent doxorubicin disrupts mitochondrial energy metabolism and redox balance in skeletal muscle

(2013) Laura A.A. Gilliam et al.   FREE RADICAL BIOLOGY AND MEDICINE

Deficits in Physical Function Among Young Childhood Cancer Survivors

(2013) Megan C. Hoffman et al.   JOURNAL OF CLINICAL ONCOLOGY

Physiologic Frailty As a Sign of Accelerated Aging Among Adult Survivors of Childhood Cancer: A Report From the St Jude Lifetime Cohort Study

(2013) Kirsten K. Ness et al.   JOURNAL OF CLINICAL ONCOLOGY

Mitochondrial pathways in sarcopenia of aging and disuse muscle atrophy

(2012) Riccardo Calvani et al.   BIOLOGICAL CHEMISTRY

Body composition changes in females treated for breast cancer: a review of the evidence

(2012) Patricia M. Sheean et al.   BREAST CANCER RESEARCH AND TREATMENT

Acrolein induction of oxidative stress and degranulation in mast cells

(2012) Daniel J. Hochman et al.   ENVIRONMENTAL TOXICOLOGY

Protective effect of Phyllanthus fraternus against mitochondrial dysfunction induced by co-administration of cisplatin and cyclophosphamide

(2012) Kavita K. Kumari et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Cardiopulmonary Function and Age-Related Decline Across the Breast Cancer Survivorship Continuum

(2012) Lee W. Jones et al.   JOURNAL OF CLINICAL ONCOLOGY

Impaired adaptability of in vivo mitochondrial energetics to acute oxidative insult in aged skeletal muscle

(2012) Michael P. Siegel et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Decline in physical functioning in first 2 years after breast cancer diagnosis predicts 10-year survival in older women

(2012) Mary Sehl et al.   Journal of Cancer Survivorship

Doxorubicin acts via mitochondrial ROS to stimulate catabolism in C2C12 myotubes

(2011) Laura A. A. Gilliam et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Chemotherapy-Induced Weakness and Fatigue in Skeletal Muscle: The Role of Oxidative Stress

(2011) Laura A.A. Gilliam et al.   ANTIOXIDANTS & REDOX SIGNALING

Strength training stops bone loss and builds muscle in postmenopausal breast cancer survivors: a randomized, controlled trial

(2011) Kerri M. Winters-Stone et al.   BREAST CANCER RESEARCH AND TREATMENT

Neuromuscular impairments in adult survivors of childhood acute lymphoblastic leukemia

(2011) Kirsten K. Ness et al.   CANCER

Ultrastructural changes in the rat kidney after single dose of cyclophosphamide—Possible roles for peroxisome proliferation and lysosomal dysfunction in cyclophosphamide-induced renal damage

(2011) Premila Abraham et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Cyclophosphamide-induced disruption of umami taste functions and taste epithelium

(2011) N. Mukherjee et al.   NEUROSCIENCE

Probucol Attenuates Cyclophosphamide-induced Oxidative Apoptosis, p53 and Bax Signal Expression in Rat Cardiac Tissues

(2011) Yousif A. Asiri   Oxidative Medicine and Cellular Longevity

Reduced Coupling of Oxidative Phosphorylation In Vivo Precedes Electron Transport Chain Defects Due to Mild Oxidative Stress in Mice

(2011) Michael P. Siegel et al.   PLoS One

Obese Frailty, Physical Performance Deficits, and Falls in Older Men with Biochemical Recurrence of Prostate Cancer on Androgen Deprivation Therapy: A Case-control Study

(2011) Kathryn Bylow et al.   UROLOGY

TNF/TNFR1 signaling mediates doxorubicin-induced diaphragm weakness

(2010) Laura A. A. Gilliam et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Improvement in self-reported physical health predicts longer survival among women with a history of breast cancer

(2010) Ruth E. Patterson et al.   BREAST CANCER RESEARCH AND TREATMENT

Physical activity, additional breast cancer events, and mortality among early-stage breast cancer survivors: findings from the WHEL Study

(2010) Lisa A. Cadmus Bertram et al.   CANCER CAUSES & CONTROL

Oxazaphosphorines: new therapeutic strategies for an old class of drugs

(2010) Bérénice Giraud et al.   Expert Opinion on Drug Metabolism & Toxicology

Long-term Prognostic Role of Functional Limitations Among Women With Breast Cancer

(2010) D. Braithwaite et al.   JNCI-Journal of the National Cancer Institute

Doxorubicin causes diaphragm weakness in murine models of cancer chemotherapy

(2010) Laura A.A. Gilliam et al.   MUSCLE & NERVE

Poor physical health predicts time to additional breast cancer events and mortality in breast cancer survivors

(2010) Nazmus Saquib et al.   PSYCHO-ONCOLOGY

Measuring musculoskeletal symptoms in cancer survivors who receive hematopoietic cell transplantation

(2010) Karen L. Syrjala et al.   Journal of Cancer Survivorship

Doxorubicin acts through tumor necrosis factor receptor subtype 1 to cause dysfunction of murine skeletal muscle

(2009) Laura A. A. Gilliam et al.   JOURNAL OF APPLIED PHYSIOLOGY

Increased Sensitivity of Glutathione S-Transferase P-Null Mice to Cyclophosphamide-Induced Urinary Bladder Toxicity

(2009) D. J. Conklin et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS