Ductular reaction correlates with fibrogenesis but does not contribute to liver regeneration in experimental fibrosis models

Imatinib accelerates progenitor cell-mediated liver regeneration in choline-deficient ethionine-supplemented diet-fed mice

(2016) András Rókusz et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Revisiting Epithelial-to-Mesenchymal Transition in Liver Fibrosis: Clues for a Better Understanding of the “Reactive” Biliary Epithelial Phenotype

(2016) Luca Fabris et al.   Stem Cells International

Hepatic Progenitor Cells in Action

(2015) Savneet Kaur et al.   AMERICAN JOURNAL OF PATHOLOGY

Loss of hepatocyte EGFR has no effect alone but exacerbates carbon tetrachloride-induced liver injury and impairs regeneration in hepatocyte Met-deficient mice

(2015) Lawrence A. Scheving et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Pathobiology of liver fibrosis: a translational success story

(2015) Youngmin A Lee et al.   GUT

Hepatocyte buds derived from progenitor cells repopulate regions of parenchymal extinction in human cirrhosis

(2015) Ashley E. Stueck et al.   HEPATOLOGY

Dissecting the role of epidermal growth factor receptor catalytic activity during liver regeneration and hepatocarcinogenesis

(2015) Judit López-Luque et al.   HEPATOLOGY

Quantitative morphometric and immunohistochemical analysis and their correlates in cirrhosis – A study on explant livers

(2015) András Rókusz et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

A novel co-operative mechanism linking TGFβ and Lyn kinase activation to imatinib resistance in chronic myeloid leukaemia cells

(2015) Andrew Chantry et al.   Oncotarget

Adult Hepatocytes Are Generated by Self-Duplication Rather than Stem Cell Differentiation

(2014) Kilangsungla Yanger et al.   Cell Stem Cell

Stem/Progenitor Cells in Liver Development, Homeostasis, Regeneration, and Reprogramming

(2014) Atsushi Miyajima et al.   Cell Stem Cell

Clonal tracing of Sox9+liver progenitors in mouse oval cell injury

(2014) Branden D. Tarlow et al.   HEPATOLOGY

Evidence against a Stem Cell Origin of New Hepatocytes in a Common Mouse Model of Chronic Liver Injury

(2014) Johanna R. Schaub et al.   Cell Reports

Conditional loss of heparin-binding EGF-like growth factor results in enhanced liver fibrosis after bile duct ligation in mice

(2013) Takayo Takemura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Prognostic Gene Expression Signature for Patients With Hepatitis C–Related Early-Stage Cirrhosis

(2013) Yujin Hoshida et al.   GASTROENTEROLOGY

Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma

(2013) Bryan C. Fuchs et al.   HEPATOLOGY

Ductular reaction in hereditary hemochromatosis: The link between hepatocyte senescence and fibrosis progression

(2013) Marnie J. Wood et al.   HEPATOLOGY

The EGFR signalling system in the liver: from hepatoprotection to hepatocarcinogenesis

(2013) Carmen Berasain et al.   JOURNAL OF GASTROENTEROLOGY

Liver Progenitor Cells Yield Functional Hepatocytes in Response to Chronic Liver Injury in Mice

(2012) Regina Español–Suñer et al.   GASTROENTEROLOGY

1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene induces substantial hyperplasia in fibrotic mouse liver

(2012) Edina Bugyik et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Anti-fibrotic activity and enhanced interleukin-6 production by hepatic stellate cells in response to imatinib mesylate

(2012) Youngchul Kim et al.   LIVER INTERNATIONAL

Liver precursor cells increase hepatic fibrosis induced by chronic carbon tetrachloride intoxication in rats

(2011) Marie-Noële Chobert et al.   LABORATORY INVESTIGATION

Ductal plates in hepatic ductular reactions. Hypothesis and implications. II. Ontogenic liver growth in childhood

(2011) Valeer J. Desmet   VIRCHOWS ARCHIV

Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver

(2010) S. Benhamouche et al.   GENES & DEVELOPMENT

Remodelling of extracellular matrix is a requirement for the hepatic progenitor cell response

(2010) Y. N. Kallis et al.   GUT

Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine

(2010) Kenichiro Furuyama et al.   NATURE GENETICS

Tyrosine kinase inhibitors for the treatment of fibrotic diseases such as systemic sclerosis: towards molecular targeted therapies

(2009) J H W Distler et al.   ANNALS OF THE RHEUMATIC DISEASES

Hepatic progenitor cell-mediated regeneration and fibrosis: Chicken or egg?

(2009) Andrew D. Clouston et al.   HEPATOLOGY

Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury

(2009) Noémi K. M. Van Hul et al.   HEPATOLOGY

The histogenesis of regenerative nodules in human liver cirrhosis

(2009) Wey-Ran Lin et al.   HEPATOLOGY

C-kit Inhibition by Imatinib Mesylate Attenuates Progenitor Cell Expansion and Inhibits Liver Tumor Formation in Mice

(2008) Belinda Knight et al.   GASTROENTEROLOGY

Lymphotoxin-β receptor signaling regulates hepatic stellate cell function and wound healing in a murine model of chronic liver injury

(2008) Richard G. Ruddell et al.   HEPATOLOGY

Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury

(2008) Erawan Borkham-Kamphorst et al.   LABORATORY INVESTIGATION

Gene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma

(2008) Yujin Hoshida et al.   NEW ENGLAND JOURNAL OF MEDICINE